Cysteine cathepsins in extracellular matrix remodeling: Extracellular matrix degradation and beyond

Vizovišek, Matej, Fonović, Marko, Turk, Boris·2019·Matrix Biology

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  3. Decoding extracellular matrix-lysosome cross-talk and its implications for neurodegenerative diseases.
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  13. In silico approaches for better understanding cysteine cathepsin-glycosaminoglycan interactions.
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  20. Molecular Perspective on Proteases: Regulation of Programmed Cell Death Signaling, Inflammation and Pathological Outcomes
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    Hanne Devos, I. Mina, F. Paradeisi, M. Makridakis, A. Tserga, M. Mokou, J. Zoidakis, H. Mischak, Antonia Vlahou, A. Latosinska et al. · 2025 · bioRxiv
  22. Upregulation of Cathepsin S Expression Contributes to Neuronal Damage Following Kainic Acid–Induced Status Epilepticus
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  56. Novel treatment strategies for cardiovascular and pulmonary diseases: Insights from cathepsin-related Mendelian randomization and Bayesian colocalization
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