Cited by 68Control Systems and IdentificationStatistical and numerical algorithmsAgriculture, Soil, Plant Science

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Determining the parametric structure of models

Cole, D.J., Morgan, B.J.T., Titterington, D.M.·2010·Mathematical Biosciences

Abstract

In this paper we develop a comprehensive approach to determining the parametric structure of models. This involves considering whether a model is parameter redundant or not and investigating model identifiability. The approach adopted makes use of exhaustive summaries, quantities that uniquely define the model. We review and generalise previous work on evaluating the symbolic rank of an appropriate derivative matrix to detect parameter redundancy, and then develop further tools for use within this framework, based on a matrix decomposition. Complex models, where the symbolic rank is difficult to calculate, may be simplified structurally using reparameterisation and by finding a reduced-form exhaustive summary. The approach of the paper is illustrated using examples from ecology, compartment modelling and Bayes networks. This work is topical as models in the biosciences and elsewhere are becoming increasingly complex.

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Metadata

Authors
Cole, D. J., Morgan, B. J. T., & Titterington, D. M.
Affiliations
  • University of Kent (GB)
  • University of Glasgow (GB)
Corresponding author
Cole, D.J.
Venue
Mathematical Biosciences
Publisher
Elsevier BV
Published
2010-11
Volume
228
Issue
1
Pages
16-30
ISSN
0025-5564 (ISSN-L)
OpenAlex
W2149396711
Cited by
68
References
1
Citations by year
2026: 1 · 2025: 2 · 2024: 4 · 2023: 2 · 2022: 3 · 2021: 6 · 2020: 7 · 2019: 8 · 2018: 3 · 2017: 3 · 2016: 4 · 2015: 2 · 2014: 8 · 2013: 6 · 2012: 5
FWCI
7.43
Type
journal article
Language
en
Open access
closed
Locations
  • Mathematical Biosciences (publishedVersion)
  • PubMed (publishedVersion)
  • ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
  • Kent Academic Repository (University of Kent) (submittedVersion)
Funders
Engineering and Physical Sciences Research Council (EP/C522702/1)
Topics
  • Physical Sciences › Engineering › Control and Systems Engineering › Control Systems and Identification
  • Physical Sciences › Mathematics › Applied Mathematics › Statistical and numerical algorithms
  • Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Agriculture, Soil, Plant Science
Keywords
parameter redundancy, model identifiability, matrix factorization, reparameterization, reduced-form models, compartmental model, Bayesian networks, ecological model
MeSH terms
Algorithms, Bayes Theorem, Models, Biological, Oxygen, Sewage, Models, Statistical, Likelihood Functions, Linear Models, Nonlinear Dynamics, Ecosystem, Computational Biology

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