The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
The biomass objective function
Open accessAbstract
Abstract / Summary Flux balance analysis (FBA) is a mathematical approach for analyzing the flow of metabolites through a metabolic network. To computationally predict cell growth using FBA, one has to determine the biomass objective function that describes the rate at which all of the biomass precursors are made in the correct proportions. Here we review fundamental issues associated with its formulation and use to compute optimal growth states.
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“Moreover, the doubling time is a critical constraint in many cellular modeling approaches such as GEMs (Feist & Palsson, 2010; Lachance et al , 2019b).”
Influential
Metadata
- Authors
- Feist, A. M., & Palsson, B. O.
- Venue
- Current Opinion in Microbiology
- Publisher
- Elsevier BV
- Published
- 2010-06
- Volume
- 13
- Issue
- 3
- Pages
- 344-349
- ISSN
- 1369-5274 (ISSN-L)
- OpenAlex
- W2029403511
- Cited by
- 607
- References
- 7
- FWCI
- 1.98
- Type
- journal article
- Language
- en
- Open access
- green
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