The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Lifestyle transitions and adaptive pathogenesis of Pseudomonas aeruginosa
Open accessAbstract
Pseudomonas aeruginosa acute and chronic infections are of great concern to human health, especially in hospital settings. It is currently assumed that P. aeruginosa has two antagonistic pathogenic strategies that parallel two different lifestyles; free-living cells are predominantly cytotoxic and induce an acute inflammatory reaction, while biofilm-forming communities cause refractory chronic infections. Recent findings suggest that the planktonic-to-sessile transition is a complex, reversible and overall dynamic differentiation process. Here, we examine how the Gac/Rsm regulatory cascade, a key player in this lifestyle switch, endows P. aeruginosa with both a permissive lifecycle in nature and flexible virulence strategy during infection.
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Citations
Cites
Pseudomonas aeruginosa : new insights into pathogenesis and host defenses
Gellatly, S. L., & Hancock, R. E. W. (2013) · Pathogens and Disease · doi:10.1111/2049-632x.12033 · Cited by 1,295
Metadata
- Authors
- Valentini, M., Gonzalez, D., Mavridou, D. A., & Filloux, A.
- Venue
- Current Opinion in Microbiology
- Publisher
- Elsevier BV
- Published
- 2018-02
- Volume
- 41
- Pages
- 15-20
- ISSN
- 1369-5274 (ISSN-L)
- OpenAlex
- W2776978775
- Cited by
- 187
- References
- 1
- FWCI
- 1.17
- Type
- journal article
- Language
- en
- Open access
- green
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- Valentini, M., Gonzalez, D., Mavridou, D. A., & Filloux, A. (2018). Lifestyle transitions and adaptive pathogenesis of Pseudomonas aeruginosa. Current Opinion in Microbiology. https://doi.org/10.1016/j.mib.2017.11.006
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
