Neural pathogenesis of enterovirus 71 infection
Open accessAbstract
Enterovirus 71 (EV71) is a neurotropic pathogen that can cause severe neural diseases and complications on infected patients. Clinical observations showed that EV71-induced immune responses may be associated with virus induced neurogenic pulmonary edema. Here reviewed studies that discovered several host molecules as potential factors for EV71 virulence.
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EV71 can cause severe complications including aseptic meningitis, encephalitis and poliomyelitis-like paralysis.
“Previous studies demonstrated EV71 can cause severe complications including aseptic meningitis, encephalitis and poliomyelitis-like paralysis [30]–[32]”
From Molecular Epidemiology of Human Enterovirus Associated with Aseptic Meningitis in Shandong Province, China, 2006–2012 (2014) · cites this paper as [32]
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References 66 · Cited by 146
- Authors
- Weng, K.-F., Chen, L.-L., Huang, P.-N., & Shih, S.-R.
- Affiliations
- Chang Gung University (TW)
- Corresponding author
- Shih, Shin-Ru
- Venue
- Microbes and Infection
- Publisher
- Elsevier BV
- Published
- 2010-07
- Volume
- 12
- Issue
- 7
- Pages
- 505-510
- ISSN
- 1286-4579 (ISSN-L)
- OpenAlex
- W2062785324
- Cited by
- 146
- References
- 66
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 7 · 2020: 5 · 2019: 9 · 2018: 9 · 2017: 13 · 2016: 10 · 2015: 14 · 2014: 24 · 2013: 16 · 2012: 9
- FWCI
- 2.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 4932 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Microbes and Infection (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
- Keywords
- enterovirus 71, neurotropism, neurogenic pulmonary edema, host factors, viral virulence, immune response, neurological complications, pathogenesis
- MeSH terms
- Enterovirus Infections, Humans, Nervous System, Nervous System Diseases, Apoptosis, Sepsis, Enterovirus A, Human, Host-Pathogen Interactions
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