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Cited by 308

The DOI matches its Crossref record; 96 of the 96 references it cites were found in a registry or an index.

Global spread of carbapenem-resistant Enterobacteriaceae: Epidemiological features, resistance mechanisms, detection and therapy

Open access
Ma, Jiayue, Song, Xiaorui, Li, Mingchao, Yu, Zengyuan, Cheng, Weyland, Yu, Zhidan, Zhang, Wancun, Zhang, Yaodong, Shen, Adong, Sun, Huiqing, Li, Lifeng·2023·Microbiological Research
DOI 10.1016/j.micres.2022.127249
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Abstract

Bacterial drug resistance has become a global public health threat, among which the infection of carbapenem-resistant Enterobacterales (CRE) is one of the top noticeable issues in the global anti-infection area due to limited therapy options. In recent years, the prevalence of CRE transmission around the world has increased, and the transmission of COVID-19 has intensified the situation to a certain extent. CRE resistance can be induced by carbapenemase, porin, efflux pump, penicillin-binding protein alteration, and biofilm production. Deletion, mutation, insertion, and post-transcriptional modification of corresponding coding genes may affect the sensitivity of Enterobacterales bacteria to carbapenems. Clinical and laboratory methods to detect CRE and explore its resistance mechanisms are being developed. Due to the limited options of antibiotics, the clinical treatment of CRE infection also faces severe challenges. The clinical therapies of CRE include single or combined use of antibiotics, and some new antibiotics and treatment methods are also being developed. Hence, this review summarizes the epidemiology, resistance mechanisms, screening and clinical treatments of CRE infection, to provide references for clinical prevention, control and treatment of CRE infection.

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Metadata

Authors
Ma, J., Song, X., Li, M., Yu, Z., Cheng, W., Yu, Z., Zhang, W., Zhang, Y., Shen, A., Sun, H., & Li, L.
Venue
Microbiological Research
Publisher
Elsevier BV
Published
2023-01
Volume
266
Pages
127249
ISSN
0944-5013 (ISSN-L)
DOI
10.1016/j.micres.2022.127249
OpenAlex
W4308194807
Cited by
308
References
96
FWCI
14.13
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Global spread of carbapenem-resistant Enterobacteriaceae: Epidemiological features, resistance mechanisms, detection and therapy. https://app.cochat.ai/papers/10.1016/j.micres.2022.127249
The paper
Ma, J., Song, X., Li, M., Yu, Z., Cheng, W., Yu, Z., Zhang, W., Zhang, Y., Shen, A., Sun, H., & Li, L. (2023). Global spread of carbapenem-resistant Enterobacteriaceae: Epidemiological features, resistance mechanisms, detection and therapy. Microbiological Research. https://doi.org/10.1016/j.micres.2022.127249

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.