ATR Kinase Activation Mediated by MutSα and MutLα in Response to Cytotoxic O6-Methylguanine Adducts

Yoshioka, Ken-ichi, Yoshioka, Yoshiko, Hsieh, Peggy·2006·Molecular Cell

Cited by (286)

Items 101–200 of 286

  1. Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1
    Wei He, Yanyan Zhao, Chunbo Zhang, L. An, Zhengyu Hu, Y. Liu, Lijuan Han, Lijun Bi, Zhensheng Xie, Peng Xue et al. · 2008 · Nucleic Acids Research
  2. PLK1 Inhibition Targets Myc-Activated Malignant Glioma Cells Irrespective of Mismatch Repair Deficiency–Mediated Acquired Resistance to Temozolomide
    Fumi Higuchi, Alexandria L. Fink, Juri Kiyokawa, Julie J. Miller, Mara V.A. Koerner, Daniel P. Cahill, Hiroaki Wakimoto · 2018 · Molecular Cancer Therapeutics
  3. Therapeutic Targeting of DNA Replication Stress in Cancer
    Long Gu, Robert J. Hickey, Linda H. Malkas · 2023 · Genes
  4. Temozolomide, Procarbazine and Nitrosoureas in the Therapy of Malignant Gliomas: Update of Mechanisms, Drug Resistance and Therapeutic Implications
    Bernd Kaina · 2023 · Journal of Clinical Medicine
  5. Distinct effects of the recurrent Mlh1 G67R mutation on MMR functions, cancer, and meiosis
    Elena Avdievich, Cora Reiß, Stefan J. Scherer, Yongwei Zhang, Sandra M. Maier, Bo Jin, Harry Hou, Andreas Rosenwald, Hubertus N. Riedmiller, Raju Kucherlapati et al. · 2008 · Proceedings of the National Academy of Sciences
  6. Reduced ATR or Chk1 Expression Leads to Chromosome Instability and Chemosensitization of Mismatch Repair–deficient Colorectal Cancer Cells
    Melanie J. Jardim, Qinhong Wang, Ryohei Furumai, Timothy P. Wakeman, Barbara K. Goodman, Xiao‐Fan Wang · 2009 · Molecular Biology of the Cell
  7. Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway
    Wen‐Cheng Chou, Ling‐Yueh Hu, Chia‐Ni Hsiung, Chen‐Yang Shen · 2015 · Carcinogenesis
  8. O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation
    Ericka M. Noonan, Dharini Shah, Michael B. Yaffe, Douglas A. Lauffenburger, Leona D. Samson · 2012 · Integrative Biology
  9. Crosstalk of DNA glycosylases with pathways other than base excision repair
    Irina V. Kovtun, Cynthia T. McMurray · 2006 · DNA repair
  10. The Versatile Attributes of MGMT: Its Repair Mechanism, Crosstalk with Other DNA Repair Pathways, and Its Role in Cancer
    Qingming Fang · 2024 · Cancers
  11. Hypothesis: Etiologic and Molecular Mechanistic Leads for Sporadic Neurodegenerative Diseases Based on Experience With Western Pacific ALS/PDC
    Peter S. Spencer · 2019 · Frontiers in Neurology
  12. Trans-lesion synthesis and mismatch repair pathway crosstalk defines chemoresistance and hypermutation mechanisms in glioblastoma
    Xing Cheng, Jing An, Jitong Lou, Qisheng Gu, Weimin Ding, Gaith N. Droby, Yilin Wang, Chenghao Wang, Yanzhe Gao, Jay Ramanlal Anand et al. · 2024 · Nature Communications
  13. Human MutL-complexes monitor homologous recombination independently of mismatch repair
    Simone Yasmin Siehler, Michael G. Schrauder, Ulrike C. Gerischer, Sharon B. Cantor, Giancarlo Marra, Lisa Wiesmüller · 2008 · DNA repair
  14. Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment
    Allen G. Schroering, Kandace J. Williams · 2008 · DNA repair
  15. MLH1- and ATM-dependent MAPK Signaling Is Activated through c-Abl in Response to the Alkylator N-Methyl-N′-nitro-N′-nitrosoguanidine
    Wan-Ju Kim, Baskaran Rajasekaran, Kevin D. Brown · 2007 · Journal of Biological Chemistry
  16. The Mismatch Repair System Modulates Curcumin Sensitivity through Induction of DNA Strand Breaks and Activation of G2-M Checkpoint
    Zhihua Jiang, Shunqian Jin, Jack C. Yalowich, Kevin D. Brown, Baskaran Rajasekaran · 2010 · Molecular Cancer Therapeutics
  17. DNA alkylation lesion repair: outcomes and implications in cancer chemotherapy
    Yihan Peng, Huadong Pei · 2021 · Journal of Zhejiang University SCIENCE B
  18. Tissue-specific mismatch repair protein expression: MSH3 is higher than MSH6 in multiple mouse tissues
    Stéphanie Tomé, Jodie P. Simard, Meghan M. Slean, Ian Holt, Glenn E. Morris, Kamila Wojciechowicz, Hein te Riele, Christopher E. Pearson · 2012 · DNA repair
  19. Modes of actions of two types of anti-neoplastic drugs, dacarbazine and ACNU, to induce apoptosis
    M. Sanada, Masumi Hidaka, Y. Takagi, T. Y. Takano, Yoshimichi Nakatsu, Teruhisa Tsuzuki, Masahiro Sekiguchi · 2007 · Carcinogenesis
  20. Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)
    Laura A. Lindsey‐Boltz, Aziz Sancar · 2011 · Journal of Biological Chemistry
  21. Atypical pituitary adenoma with MEN1 somatic mutation associated with abnormalities of DNA mismatch repair genes; MLH1 germline mutation and MSH6 somatic mutation
    Shinsuke Uraki, Hiroyuki Ariyasu, Asako Doi, Hiroto Furuta, Masahiro Nishi, Kokichi Sugano, Naoko Inoshita, Naoyuki Nakao, Shozo Yamada, Takashi Akamizu · 2017 · Endocrine Journal
  22. Reduced Expression of Mismatch Repair Genes MSH6/MSH2 Directly Promotes Pituitary Tumor Growth via the ATR–Chk1 Pathway
    Shinsuke Uraki, Hiroyuki Ariyasu, Asako Doi, Shintaro Kawai, Ken Takeshima, Shuhei Morita, Junya Fukai, Koji Fujita, Hiroto Furuta, Masahiro Nishi et al. · 2018 · The Journal of Clinical Endocrinology & Metabolism
  23. Human Pluripotent Stem Cells Have a Novel Mismatch Repair-dependent Damage Response
    Bo Lin, Dipika Gupta, Christopher D. Heinen · 2014 · Journal of Biological Chemistry
  24. Biochemical Analysis of the Human Mismatch Repair Proteins hMutSα MSH2G674A-MSH6 and MSH2-MSH6T1219D
    Hui Zhi Geng, Miho Sakato, Vanessa DeRocco, Kazuhiko Yamane, Chunwei Du, Dorothy A. Erie, Manju Hingorani, Peggy Hsieh · 2012 · Journal of Biological Chemistry
  25. The Mismatch-Binding Factor MutSβ Can Mediate ATR Activation in Response to DNA Double-Strand Breaks
    Kamila Burdová, Boris Mihaljević, Andreas Sturzenegger, Nagaraja Chappidi, Pavel Janščák · 2015 · Molecular Cell
  26. Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots
    Xia Cao, Hetong Wang, Defeng Zhuang, He Zhu, Yanli Du, Zhibo Cheng, Weina Cui, Hilary Joan Rogers, Qianru Zhang, Chunjun Jia et al. · 2018 · Chemosphere
  27. Onset of Quiescence Following p53 Mediated Down-Regulation of H2AX in Normal Cells
    Yuko Atsumi, Hiroaki Fujimori, Hirokazu Fukuda, Aki Inase, Keitaro Shinohe, Yoshiko Yoshioka, Mima Shikanai, Yosuke Ichijima, Junya Unno, Shuki Mizutani et al. · 2011 · PLoS ONE
  28. In vitro studies of DNA mismatch repair proteins
    Hui Zhi Geng, Chunwei Du, Siying Chen, Vincenzo Salerno, Candela Manfredi, Peggy Hsieh · 2011 · Analytical Biochemistry
  29. Expression of Concern: Therapeutic targeting of chemoresistant and recurrent glioblastoma stem cells with a proapoptotic variant of oncolytic herpes simplex virus
    Nusrat Jahan, Jae Moo Lee, Khalid Shah, Hiroaki Wakimoto · 2017 · International Journal of Cancer
  30. DNA Mismatch Repair-dependent Activation of c-Abl/p73α/GADD45α-mediated Apoptosis
    Long Shan Li, Julio C. Morales, Arlene Hwang, Mark W. Wagner, David A. Boothman · 2008 · Journal of Biological Chemistry
  31. Cellular senescence in glioma
    Rafał Chojak, Jawad Fares, Edgar Petrosyan, Maciej S. Lesniak · 2023 · Journal of Neuro-Oncology
  32. Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice
    Zheng Fu, Kevin M. Regan, Lizhi Zhang, Michael H. Muders, Stephen N. Thibodeau, Amy J. French, Yanhong Wu, Scott H. Kaufmann, Wilma L. Lingle, Junjie Chen et al. · 2009 · Journal of Clinical Investigation
  33. Function of high-mobility group A proteins in the DNA damage signaling for the induction of apoptosis
    Ryosuke Fujikane, Kayoko Komori, Mutsuo Sekiguchi, Masumi Hidaka · 2016 · Scientific Reports
  34. Crosstalk between repair pathways elicits double-strand breaks in alkylated DNA and implications for the action of temozolomide
    Robert P. Fuchs, Asako Isogawa, João A. Paulo, Kazumitsu Onizuka, Tatsuro S. Takahashi, Ravindra Amunugama, Julien P. Duxin, 慎吾 藤井 · 2021 · eLife
  35. Bifunctional DNA Alkylator 1,3-Bis(2-chloroethyl)-1-nitrosourea Activates the ATR-Chk1 Pathway Independently of the Mismatch Repair Pathway
    B. Cui, S P Johnson, N. Bullock, Francis Ali‐Osman, Darell D. Bigner, Henry S. Friedman · 2009 · Molecular Pharmacology
  36. Success and Failures of Combined Modalities in Glioblastoma Multiforme: Old Problems and New Directions
    Christopher D. Corso, Ranjit S. Bindra · 2016 · Seminars in Radiation Oncology
  37. MutS functions as a clamp loader by positioning MutL on the DNA during mismatch repair
    Xiaowen Yang, Xiao-Peng Han, Chong Han, James A. London, Richard A. Fishel, Jiaquan Liu · 2022 · Nature Communications
  38. The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
    Michael G. Kemp, Laura A. Lindsey‐Boltz, Aziz Sancar · 2011 · Journal of Biological Chemistry
  39. MutL: conducting the cell's response to mismatched and misaligned DNA
    Yaroslava Y. Polosina, Claire G. Cupples · 2009 · BioEssays
  40. ATR–Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity
    Yoshihiko Fujinaka, Kazuaki Matsuoka, Makoto Iimori, Munkhbold Tuul, Ryo Sakasai, Keiji Yoshinaga, Hiroshi Saeki, Masaru Morita, Yoshihiro Kakeji, David A. Gillespie et al. · 2011 · DNA repair
  41. Mismatch repair causes the dynamic release of an essential DNA polymerase from the replication fork
    Andrew D. Klocko, Jeremy W. Schroeder, Brian W. Walsh, Justin S. Lenhart, Margery L. Evans, Lyle A. Simmons · 2011 · Molecular Microbiology
  42. The Complex Roles of DNA Repair Pathways, Inhibitors, Hyperthermia, and Contact Inhibition in Cell Cycle Halts
    Young Sup Lee, Muhammad Bilal Ahmed, Abdullah A. A. Alghamdi, Salman Ul Islam, Haseeb Ahsan · 2022 · Mini-Reviews in Medicinal Chemistry
  43. The Arf/p53 Protein Module, Which Induces Apoptosis, Down-regulates Histone H2AX to Allow Normal Cells to Survive in the Presence of Anti-cancer Drugs
    Yuko Atsumi, Aki Inase, Tomoyuki Osawa, Eiji Sugihara, Ryo Sakasai, Hiroaki Fujimori, Hirobumi Teraoka, Hideyuki Saya, Masamoto Kanno, Fumio Tashiro et al. · 2013 · Journal of Biological Chemistry
  44. Double-strand breaks: When DNA repair events accidentally meet
    慎吾 藤井, Robert William Sobol, Robert P. Fuchs · 2022 · DNA repair
  45. Nuclear reorganization of DNA mismatch repair proteins in response to DNA damage
    Adam S. Mastrocola, Christopher D. Heinen · 2009 · DNA repair
  46. Linking arsenite- and cadmium-generated oxidative stress to microsatellite instability in vitro and in vivo
    Chang‐Lin Wu, Liyan Huang, Christina Ling Chang · 2017 · Free Radical Biology and Medicine
  47. Mismatch repair proteins play a role in ATR activation upon temozolomide treatment in MGMT-methylated glioblastoma
    Sachita Ganesa, Amrita D. Sule, Ranjini K. Sundaram, Ranjit S. Bindra · 2022 · Scientific Reports
  48. Spectrum of DNA mismatch repair failures viewed through the lens of cancer genomics and implications for therapy
    David Mas-Ponte, Marcel McCullough, Fran Supek · 2022 · Clinical Science
  49. Orc6 is a component of the replication fork and enables efficient mismatch repair
    Yo-Chuen Lin, Dazhen Liu, Arindam Chakraborty, Lyudmila Y. Kadyrova, You Jin Song, Qinyu Hao, Jaba Mitra, Rosaline Y.C. Hsu, Mariam K. Arif, Sneha Adusumilli et al. · 2022 · Proceedings of the National Academy of Sciences
  50. Modulation of MutS ATP-dependent Functional Activities by DNA containing a Cisplatin Compound Lesion (Base Damage and Mismatch)
    Yuliya Sedletska, Laurence Fourrier, Jean‐Marc Malinge · 2007 · Journal of Molecular Biology
  51. Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1
    Haibo Bai, Amrita Madabushi, Xin Guan, A-Lien Lu · 2010 · DNA repair
  52. REVIEWS IN BASIC AND CLINICAL GASTROENTEROLOGY
    John P. Lynch, David C. Metz, Detlef Schuppan, Yvonne Junker, Donatella Barisani · 2009
  53. Decoupling of DNA damage response signaling from DNA damages underlies temozolomide resistance in glioblastoma cells
    Bo Cui, Stewart P. Johnson, N. Bullock, Francis Ali‐Osman, Darell D. Bigner, Henry S. Friedman · 2010 · Journal of Biomedical Research
  54. Genetic predisposition to lymphomas: Overview of rare syndromes and inherited familial variants
    Bartosz M. Szmyd, Wojciech Michal Mlynarski, Agata Karolina Pastorczak · 2021 · Mutation Research/Reviews in Mutation Research
  55. RAD51D protects against MLH1-dependent cytotoxic responses to O6-methylguanine
    Preeti Rajesh, Changanamkandath Rajesh, Michael D. Wyatt, Douglas L. Pittman · 2010 · DNA repair
  56. An MLH1 Mutation Links BACH1/FANCJ to Colon Cancer, Signaling, and Insight toward Directed Therapy
    Jenny Xie, Shawna Guillemette, Min Peng, Candace A. Gilbert, Andrew B. Buermeyer, Sharon B. Cantor · 2010 · Cancer Prevention Research
  57. Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy
    José L. McFaline‐Figueroa, Sanjay R Srivatsan, Andrew J. Hill, Molly J. Gasperini, Dana L. Jackson, Lauren M. Saunders, Silvia Domcke, Samuel G. Regalado, Paul Lazarchuck, Sarai Alvarez et al. · 2024 · Cell Genomics
  58. N-Methyl-N′-nitro-N-nitrosoguanidine (MNNG) Triggers MSH2 and Cdt2 Protein-dependent Degradation of the Cell Cycle and Mismatch Repair (MMR) Inhibitor Protein p21Waf1/Cip1
    Thomas A. Jascur, Rati Fotedar, Serena Greene, Erin C. Hotchkiss, Clement Richard Boland · 2011 · Journal of Biological Chemistry
  59. Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q
    Ivana Marinovic‐Terzić, Atsuko Yoshioka-Yamashita, Hideki Shimodaira, Elena Avdievich, Irina C. Hunton, Richard David Kolodner, Winfried Edelmann, Jean Y. J. Wang · 2008 · Proceedings of the National Academy of Sciences
  60. Distinct Phenotypes Caused by Mutation of MSH2 in Trypanosome Insect and Mammalian Life Cycle Forms Are Associated with Parasite Adaptation to Oxidative Stress
    Viviane Grazielle-Silva, Tehseen Fatima Zeb, Jason Bolderson, Priscila Carneiro Campos, Júlia Bahia Miranda, Ceres Luciana Alves, Carlos Renato Machado, Richard McCulloch, Santuza Maria Ribeiro Teixeira · 2015 · PLoS neglected tropical diseases
  61. Mismatch repair-dependent metabolism of O 6 -methylguanine-containing DNA in Xenopus laevis egg extracts
    Maite Olivera Harris, Lia Kallenberger, Mariela Susana Borán, Milica Enoiu, Vincenzo Costanzo, Josef Jiricny · 2015 · DNA repair
  62. Wot the ‘L—Does MutL do?
    Yaroslava Y. Polosina, Claire G. Cupples · 2010 · Mutation Research/Reviews in Mutation Research
  63. Alkylation damage causes MMR-dependent chromosomal instability in vertebrate embryos
    Harma Feitsma, Alper Akay, Edwin P. J. G. Cuppen · 2008 · Nucleic Acids Research
  64. Knock-down of human MutY homolog (hMYH) decreases phosphorylation of checkpoint kinase 1 (Chk1) induced by hydroxyurea and UV treatment
    Soo-Hyun Hahm, Jong-Hwa Park, Sung Il Ko, You-Ri Lee, In-Sik Chung, Ji-Hyung Chung, Lin‐Woo Kang, Ye-Sun Han · 2011 · BMB Reports
  65. Comprehensive whole-genome sequencing reveals origins of mutational signatures associated with aging, mismatch repair deficiency and temozolomide chemotherapy
    Taejoo Hwang, Lukasz Karol Sitko, Ratih Khoirunnisa, Fernanda Navarro Aguad, David M Samuel, Hajoong Park, Banyoon Cheon, Luthfiyyah Mutsnaini, Jaewoong Lee, Burçak Otlu et al. · 2024 · Nucleic Acids Research
  66. Alkyltransferase-like protein (eATL) prevents mismatch repair-mediated toxicity induced by O 6 -alkylguanine adducts in Escherichia coli
    Gerard Mazón, Gaëlle Philippin, Jean Cadet, Didier Gasparutto, Mauro Modesti, Robert P. Fuchs · 2010 · Proceedings of the National Academy of Sciences
  67. Excision of translesion synthesis errors orchestrates responses to helix-distorting DNA lesions
    Anastasia Tsaalbi‐Shtylik, Cristina Ferrás, Bea Pauw, Giel Hendriks, Piya Temviriyanukul, Leone Carlée, Fabienne M.G.R. Calléja, Sandrine van Hees‐Stuivenberg, Jun‐ichi Akagi, Shigenori Iwai et al. · 2015 · The Journal of Cell Biology
  68. Nijmegen Breakage Syndrome Protein (NBN) Causes Resistance to Methylating Anticancer Drugs Such as Temozolomide
    Marcus Eich, Wynand Paul Roos, Grigory L. Dianov, Martin Digweed, Bernd Kaina · 2010 · Molecular Pharmacology
  69. Histone/protein deacetylase SIRT1 is an anticancer therapeutic target.
    Bor‐Jang Hwang, Amrita Madabushi, Jin Jin, Shiou-Yuh Lin, A-Lien Lu · 2014 · PubMed Central
  70. Combining modularity, conservation, and interactions of proteins significantly increases precision and coverage of protein function prediction
    Samira Jaeger, Christine Sers, Ulf Leser · 2010 · BMC Genomics
  71. High-fidelity correction of genomic uracil by human mismatch repair activities
    Erik D. Larson, David W. Bednarski, Nancy Maizels · 2008 · BMC Molecular Biology
  72. Pericentromeric Satellite III transcripts induce etoposide resistance
    Julian Kanne, Michelle Hussong, Jörg Isensee, Álvaro Muñoz‐López, Jan Wolffgramm, Felix Heß, Christina Grimm, Sergey Bessonov, Lydia Meder, Jie Wang et al. · 2021 · Cell Death and Disease
  73. Interplay between H3K36me3, methyltransferase SETD2, and mismatch recognition protein MutSα facilitates processing of oxidative DNA damage in human cells
    Sida Guo, Jun Fang, Weizhi Xu, Janice Ortega, Chang-Yi Liu, Liya Gu, Zhijie Chang, Guo‐Min Li · 2022 · Journal of Biological Chemistry
  74. Interplay of DNA Repair Pathways Controls Methylation Damage Toxicity in Saccharomyces cerevisiae
    Petr Ćejka, Josef Jiricny · 2008 · Genetics
  75. Mismatch repair dependence of replication stress-associated DSB recognition and repair
    Haruka Fujimori, Mai Hyodo, Yusuke Matsuno, Atsuhiro Shimizu, Yusuke Minakawa, Yuko Atsumi, Yoshimichi Nakatsu, Teruhisa Tsuzuki, Yasufumi Murakami, Kenichi Yoshioka · 2019 · Heliyon
  76. A novel protein, MAPO1, that functions in apoptosis triggered by O6-methylguanine mispair in DNA
    K Komori, Y Takagi, M Sanada, T-H Lim, Yoshimichi Nakatsu, Teruhisa Tsuzuki, Masahiro Sekiguchi, Masumi Hidaka · 2009 · Oncogene
  77. Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan
    Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz et al. · 2013 · International Journal of Oncology
  78. Different initial steps of apoptosis induced by two types of antineoplastic drugs
    Yasumitsu Takagi, Masumi Hidaka, Masayuki Sanada, Hiroki Yoshida, Mutsuo Sekiguchi · 2008 · Biochemical Pharmacology
  79. The Recombinant Oncolytic Virus VV-GMCSF-Lact and Chemotherapy Drugs against Human Glioma
    Natalia S. Vasileva, Alisa B. Ageenko, Arina A. Byvakina, Сенькова Александра Васильевна, Galina V. Kochneva, Sergey V. Mishinov, Vladimir Alexandrovich Richter, Elena Vladimirovna Kuligina · 2024 · International Journal of Molecular Sciences
  80. A CRM1‐dependent nuclear export pathway is involved in the regulation of MutLα subcellular localization
    Angela Brieger, R. Adam, Sandra Passmann, Guido Plotz, Stefan Zeuzem, Jörg Trojan · 2010 · Genes Chromosomes and Cancer
  81. Prolonged Cell Cycle Response of HeLa Cells to Low-Level Alkylation Exposure
    Allen G. Schroering, Anbarasi Kothandapani, Steve M. Patrick, Kaliyaperumal Saravanan, Vishal Premdev Sharma, Kandace J. Williams · 2009 · Cancer Research
  82. Mismatch repair enhances convergent transcription-induced cell death at trinucleotide repeats by activating ATR
    Nimrat Chatterjee, Yunfu Lin, John H. Wilson · 2016 · DNA repair
  83. Carmustine-Resistant Cancer Cells Are Sensitized to Temozolomide As A Result of Enhanced Mismatch Repair during the Development of Carmustine Resistance
    Takahiro Yamauchi, Masami Ogawa, Takanori Ueda · 2008 · Molecular Pharmacology
  84. Exonuclease 1 (Exo1) is required for activating response to SN1 DNA methylating agents
    Eugene Izumchenko, John Saydi, Kevin D. Brown · 2012 · DNA repair
  85. The Identification of a Novel Gene, MAPO2, That Is Involved in the Induction of Apoptosis Triggered by O6-Methylguanine
    Ryosuke Fujikane, Masayuki Sanada, Mutsuo Sekiguchi, Masumi Hidaka · 2012 · PLoS ONE
  86. MLH1-deficient HCT116 colon tumor cells exhibit resistance to the cytostatic and cytotoxic effect of the poly(A) polymerase inhibitor cordycepin (3′-deoxyadenosine) in vitro
    Patrick Imesch, Anouk Goerens, Daniel A. Fink, André Fedier · 2011 · Oncology Letters
  87. Arf and p53 act as guardians of a quiescent cellular state by protecting against immortalization of cells with stable genomes
    Tomoyuki Osawa, Yuko Atsumi, Eiji Sugihara, Hideyuki Saya, Masamoto Kanno, Fumio Tashiro, Mitsuko Masutani, Kenichi Yoshioka · 2013 · Biochemical and Biophysical Research Communications
  88. Does a helicase activity help mismatch repair in eukaryotes?
    Limin Song, Fenghua Yuan, Yanbin Zhang · 2010 · IUBMB Life
  89. Molecular devices for high fidelity of DNA replication and gene expression
    Mutsuo Sekiguchi · 2006 · Proceedings of the Japan Academy Series B
  90. Multiple ATR-Chk1 Pathway Proteins Preferentially Associate with Checkpoint-Inducing DNA Substrates
    Seçil Yilmaz, Aziz Sancar, Michael G. Kemp · 2011 · PLoS ONE
  91. MiR-137 Targets the 3′ Untranslated Region of MSH2: Potential Implications in Lynch Syndrome-Related Colorectal Cancer
    Raffaella Liccardo, Raffaele Sessa, Silvia Trombetti, Marina De Rosa, Paola Izzo, Michela Grosso, Francesca Duraturo · 2021 · Cancers
  92. SLX4 dampens MutSα-dependent mismatch repair
    Jean-Hugues Guervilly, Marion Blin, Luisa Laureti, Émilie Baudelet, Stéphane Audebert, Pierre-Henri L. Gaillard · 2022 · Nucleic Acids Research
  93. Phosphorylated hMSH6: DNA mismatch versus DNA damage recognition
    Kaliyaperumal Saravanan, Steve M. Patrick, Kandace J. Williams · 2010 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  94. Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue, and correlation with mutation frequency
    Kentaro Taira, Shintaro Nakamura, Khota Nakano, Daisuke Maehara, Keinosuke Okamoto, Sakae Arimoto, David Loakes, Leroy Worth, Roel M. Schaaper, Kohji Seio et al. · 2008 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  95. A novel DNA damage response mediated by DNA mismatch repair in Caenorhabditis elegans: induction of programmed autophagic cell death in non-dividing cells
    Takahito Moriwaki, Yuichi Kato, Chihiro Nakamura, Satoru Ishikawa, Qiu-Mei Zhang-Akiyama · 2015 · Genes & Cancer
  96. Repair of O6-carboxymethylguanine adducts by O6-methylguanine-DNA methyltransferase in human colon epithelial cells
    Tina Kostka, Michael T. Empl, Nina Seiwert, Susanne M. Geisen, Pascal Hoffmann, Janine Adam, Bettina Seeger, Jerry W. Shay, Markus Christmann, Shana J. Sturla et al. · 2021 · Carcinogenesis
  97. Mismatch Repair
    Richard A. Fishel, Jong‐Bong Lee · 2016 · Springer eBooks
  98. How to sensitize glioblastomas to temozolomide chemotherapy: a gap-centered view
    Alila Miramova, Anton Gartner, Dmitri Ivanov · 2024 · Frontiers in Cell and Developmental Biology
  99. Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities
    Qiuming Pan, Zhu Ye, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu et al. · 2025 · BMEMat
  100. Embryonic Lethality after Combined Inactivation of Fancd2 and Mlh1 in Mice
    Henri J. van de Vrugt, Laura Eaton, Amy Hanlon Newell, Mushen Al-Dhalimy, R. Michael Liskay, Susan B. Olson, Markus Grompe · 2009 · Cancer Research