Sch9 Is a Major Target of TORC1 in Saccharomyces cerevisiae

Urban, Jörg; Soulard, Alexandre; Huber, Alexandre; Lippman, Soyeon; Mukhopadhyay, Debdyuti; Deloche, Olivier; Wanke, Valeria; Anrather, Dorothea; Ammerer, Gustav; Riezman, Howard; Broach, James R.; De Virgilio, Claudio; Hall, Michael N.; Loewith, Robbie

doi:10.1016/j.molcel.2007.04.020

Sch9 Is a Major Target of TORC1 in Saccharomyces cerevisiae

The Target of Rapamycin (TOR) protein is a Ser/Thr kinase that functions in two distinct multiprotein complexes: TORC1 and TORC2. These conserved complexes regulate many different aspects of cell growth in response to intracellular and extracellular cues. Here we report that the AGC kinase Sch9 i…