The DOI matches its Crossref record; 165 of the 165 references it cites were found in a registry or an index.
The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets
Open accessAbstract
Summary The abundant nuclear enzyme PARP-1, a multifunctional regulator of chromatin structure, transcription, and genomic integrity, plays key roles in a wide variety of processes in the nucleus. Recent studies have begun to connect the molecular functions of PARP-1 to specific physiological and pathological outcomes, many of which can be altered by an expanding array of chemical inhibitors of PARP enzymatic activity.
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Cites
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Combinatorial patterns of histone acetylations and methylations in the human genome
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Cited by
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Houtkooper, R. H., Pirinen, E., & Auwerx, J. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3293 · Cited by 2,008
Crosstalk between apoptosis.; necrosis and autophagy
Nikoletopoulou, V., Markaki, M., Palikaras, K., & Tavernarakis, N. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2013.06.001 · Cited by 1,366
“As already mentioned earlier, PARP1 belongs to a family of nuclear enzymes, modulating DNA repair, transcriptional regulation, chromatin modification and genomic stability through polyADP-ribosylation [131,132].”
BackgroundNew insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
Gibson, B. A., & Kraus, W. L. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3376 · Cited by 1,226
Self-citationDynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
Polo, S. E., & Jackson, S. P. (2011) · Genes & Development · doi:10.1101/gad.2021311 · Cited by 1,092
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
Bai, P., Cantó, C., Oudart, H., Brunyánszki, A., Cen, Y., Thomas, C., Yamamoto, H., Huber, A., Kiss, B., Houtkooper, R. H., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.03.004 · Cited by 837
Metadata
- Authors
- Krishnakumar, R., & Kraus, W. L.
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 2010-07
- Volume
- 39
- Issue
- 1
- Pages
- 8-24
- ISSN
- 1097-2765 (ISSN-L)
- OpenAlex
- W1992397774
- Cited by
- 836
- References
- 165
- FWCI
- 31.34
- Type
- journal article
- Language
- en
- Open access
- bronze
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