Extracellular Regulated Kinase Phosphorylates Mitofusin 1 to Control Mitochondrial Morphology and Apoptosis

Pyakurel, Aswin, Savoia, Claudia, Hess, Daniel, Scorrano, Luca·2015·Molecular Cell

Cited by (244)

Items 201–244 of 244

  1. Fludioxonil compromises cellular homeostasis in and viability in bovine mammary epithelial cells by inducing mitochondrial dysfunction and calcium dysregulation
    Shin‐Hye Kim, Junhun Kweon, Hojun Lee, Gwonhwa Song, Whasun Lim, Wooyoung Jeong · 2025 · Pesticide Biochemistry and Physiology
  2. The protective effect of 20(S)-ginsenoside Rg3 on the human retinal pigment epithelial cells against hydrogen peroxide-induced oxidative stress
    Bo Kyeong Kim, Ki‐Uk Kim, Jisu Kim, Hyunjun Jang, Hyeyoung Min · 2024 · Food Science and Biotechnology
  3. Therapeutic Effects and Mechanisms of Icaritin in Parkinson's Disease
    Chongbo Zheng, Lizhen Wu, Liang Luo, Jiating Cai, Zhihua Huang, Keqiang Tian · 2025 · Current Pharmaceutical Design
  4. Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology
    Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou · 2025 · The Journal of Physiology
  5. The emerging role of circular RNAs in neuropsychiatric disorders
    Shihao Huang, Zhihao Song, Jiayue Pan, Yixiao Luo, Yun Chen · 2025 · Translational Psychiatry
  6. Regulation of mitochondrial biogenesis and energy metabolism in the heart
    Peilu She, 莫非, Ping Zhu, Tao P. Zhong · 2026 · Chinese Medical Journal
  7. Dimeric PKM2 in chondrocytes impairs mitochondrial homeostasis in osteoarthritis
    Bo Liu, Yun Liang, Chenzhong Wang, Ziyu Weng, Yi Yang, Yi Shi, Chenchun Zhang · 2026 · Cell Death and Disease
  8. Mitochondrial metallopeptidase OMA1 in cancer
    Gunjan Purohit, Polash Ghosh, Oleh Khalimonchuk · 2024 · Advances in cancer research
  9. New prognostic features and personalized treatment strategies of mitochondrial related genes in colorectal cancer patients
    Qiaobing Xu, Zhiwen Wang, Shan-Tao Huang, Jiayu Shi, Yan Zhu, Han‐Qing Pang · 2025 · Frontiers in Pharmacology
  10. Loss of Drosophila ribosomal protein S6 kinase II causes mitochondrial dysfunction and cell death
    Ting Deng, Lajos Kalmár, Samantha H. Y. Loh, Olivier E. Pardo, L. Miguel Martins · 2025 · Disease Models & Mechanisms
  11. Protein Kinases and Regulation of Mitochondrial Function in Ischemia/Reperfusion Injury
    Grażyna Nowak · 2018 · InTech eBooks
  12. Galectin-8 drives ERK-dependent mitochondrial fragmentation, perinuclear relocation and mitophagy, with metabolic adaptations for cell proliferation
    Adely de la Peña, Cláudio Retamal, Francisca Pérez-Molina, Nicole Díaz-Valdivia, Francisco Veloso-Bahamondes, Diego Tapia, Jorge Cancino, Felix Randow, Alfonso González, Claudia Oyanadel et al. · 2025 · European Journal of Cell Biology
  13. Mitochondrial Health and Critical Neurotransmitters in Neurodegeneration
    Nisha Sharma, Manav Jain, Umashanker Navik · 2026 · Springer eBooks
  14. Mitochondrial dynamics and cancer: mechanisms and targeted therapy
    Aixin Wang, Xinyu Ye, Yulin Zhao, Chao Zhang · 2026 · Cell Biology and Toxicology
  15. MAPK-driven remodeling of mitochondrial dynamics in melanoma: implications for metabolic plasticity and response to targeted therapy
    Laura Francisca Leite do Prado-Souza, Lorraine A. Grabauskas, R. Chaguri, C. D. Cardoso, F.Y. Urushima, L.G.R. Mangini, V.S. Ramos, Tiago Rodrigues · 2026 · Biochemical Pharmacology
  16. Mitochondrial Dynamics: A Journey from Mitochondrial Morphology to Mitochondrial Function and Quality
    David Sebastián, António Zorzano · 2018 · Springer eBooks
  17. Transcriptional Profiles of Mitochondrial Dynamics Markers Are Disturbed in Adrenal Glands of Stressed Adult Male Rats
    Isidora M. Keselj, Filip N. Bozic, Miodrag M. Vucinic, Dušan Lalošević, Tatjana S. Kostic, Silvana A. Andrić · 2023 · Life
  18. Spermatozoal Mitochondrial Dynamics Markers and Other Functionality-Related Signaling Molecules Exert Circadian-like Response to Repeated Stress of Whole Organism
    Isidora M. Starovlah, Sava M. Radovic Pletikosic, Tamara M. Tomanic, Marija Lj Medar, Tatjana S. Kostic, Silvana A. Andrić · 2022 · Cells
  19. Spermatozoa Develop Molecular Machinery to Recover From Acute Stress
    Isidora M. Starovlah, Sava M. Radovic Pletikosic, Tamara M. Tomanic, Marija Lj Medar, Tatjana S. Kostic, Silvana A. Andrić · 2022 · Frontiers in Endocrinology
  20. Analysis of the apoptotic threshold at the onset of embryonic differentiation
    Sanchez Nieto · 2015 · Spiral (Imperial College London)
  21. Intratumoral heterogeneity for frameshift mutations of TP53BP1 and MFN1 genes in colorectal cancers
    Eun Ji Choi, Min Sung Kim, Nam Jin Yoo, Sug Hyung Lee · 2018 · Pathology - Research and Practice
  22. Altered mitochondrial dynamics in a novel cellular model of Leber Hereditary Optic Neuropathy (LHON)
    Kolitha Halangoda · 2018 · Summit (Simon Fraser University)
  23. On the Regulation of Mitochondrial Fusion, Fission and Mitochondrial DNA
    Rasha Sabouny · 2020
  24. Mitochondrial Dynamics and Stress Signaling in Cancer
    Camila Rubio‐Patiño, Jerry E. Chipuk · 2021 · Oxford University Press eBooks
  25. Characterisation of the ghrelinergic system in human models of neurodegenerative diseases
    Maria Carla Carisi · 2021
  26. Identification of Mfn2-S249 as a Phosphoregulatory Switch of Mitochondrial Fusion Dynamics
    Sanjay Kumar, Aaron Ramonett, Tasmia Ahmed, Eun‐A Kwak, Paola Cruz Flores, Hannah R. Ortiz, Paul R. Langlais, Karthikeyan Mythreye, Nam Y. Lee · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  27. Additional file 1 of A novel diabetic foot ulcer diagnostic model: identification and analysis of genes related to glutamine metabolism and immune infiltration
    Shi, Hongshuo, Xin Yuan, Xiao Yang, Huang, Renyan, Fan, Weijing, Guobin Liu · 2024 · Figshare
  28. Mitochondrial fission and fusion: immunologic approach
    Hossein Naghiloo, Sara Sadaghian, Seyyed Shamsadin Athari, Davood Jafari · 2025 · Elsevier eBooks
  29. Neuronal mitochondrial dynamics: roles in brain disorders and therapeutic potential
    Xingxian Zhang, Jiamin Du, Shen-zhan Wang, Xinlei Mo, Xiangnan Zhang · 2026 · Acta Pharmacologica Sinica
  30. Étude des liens entre les acteurs de la dynamique mitochondriale et l'apoptose dans la dégénérescence musculaire dystrophinedépendante chez Caenorhabditis elegans
    Charlotte Scholtes · 2018 · theses.fr (ABES)
  31. Rôle de la dynamique mitochondriale à la phase aigue de l'infarctus du myocarde
    Laura Cellier · 2017 · theses.fr (ABES)
  32. Implication des protéines BNIP3 et OPA1 dans la balance entre survie par autophagie-mitophagie et mort par apoptose dans les neurones
    Manon Moulis · 2016 · theses.fr (ABES)
  33. Étude des évènements mitochondriaux impliqués dans le contrôle de l'apoptose par rbf1, l'homologue de drosophile du gène suppresseur de tumeur rb
    Vincent Ruby · 2018 · theses.fr (ABES)
  34. Rôle des vésicules extracellulaires sécrétées par les adipocytes dans la progression du mélanome : impact de l'obésité
    Emily Clement · 2018 · theses.fr (ABES)
  35. High-throughput mitochondrial morphology screen identifies PGS1 as a functional suppressor of mitochondrial fragmentation in patient-derived OPA1 mutant fibroblasts
    Emma Cretin · 2021 · theses.fr (ABES)
  36. Étude d’une mitofusine atypique impliquée dans la dynamique mitochondriale chez Trypanosoma brucei
    Chloé Morel · 2023 · theses.fr (ABES)
  37. Mise en lumière de la diversité phénotypique au sein d'une série allélique de mitofusine de drosophile mimant des mutations associées à la maladie de Charcot-Marie-Tooth de type 2A
    OLENA O. VARUK · 2023 · theses.fr (ABES)
  38. β 1 /β 2 adrenergic dysregulation: a missing link between mitochondrial fission/fusion in the failing heart
    Pranav Panchbhai, Gauri Chaturvedi, Satnam Singh, Nandini Dubey, Rajiv Narang, Neeraj Parakh, Prabhakar Singh, Upendra Baitha, Ved Prakash, Harlokesh Narayan Yadav · 2026 · Journal of Receptors and Signal Transduction
  39. Fonctions mitochondriales de la protéine Optineurine : neurodégénérescence et cancer
    Baptiste D’Urso · 2025
  40. Deciphering Bax Dynamics: Regulation, Retrotranslocation, and Mitochondrial Interplay in the Commitment to Apoptosis: A Narrative Review
    Mehrin Haque Tanisha, Md. Ayman Siddique, Zubaier Ahmed, Nashrah Mustafa, Fariha Tasneem · 2026 · Health Science Reports
  41. Investigation of the modulatory effects of fabomotizole and/or sertraline on cisplatin nephrotoxicity via in vivo and in vitro approaches: insights into the role of Sig-1R/ERK1/2 signaling in regulating mitochondrial dynamics and apoptotic cellular death
    Aya M. Zaki, Mohamed A. Khattab, Dalia M. El-Tanbouly, Rania M. Abdelsalam, Hala Fahmy Zaki, Tarek M. Abdelghany · 2026 · Naunyn-Schmiedeberg s Archives of Pharmacology
  42. Nuclear DNA Damage Response Triggers Reorganization of Mitochondrial Nucleic Acids
    Chenxiao Yu, Emma Evens, Sidney Tchiong, Marite Castromonte Albinagorta, Joshua Okletey, Marco Tigano · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  43. Targeting regulated cell death-related serine/threonine kinases to combat neurodegenerative disorders
    Heba Mohamed Mansour, Aiman Saad El-Khatib · 2026 · Elsevier eBooks
  44. Senp1 O-GlcNAcylation Promotes Mitochondrial Fragmentation by Regulating Fis1 SUMO1-ylation Underlying Diabetic Cataract
    Zaoxia Guo, Xinnan Li, X M Chen, Xiaopan Ma, Hong Yan · 2026 · Investigative Ophthalmology & Visual Science