The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

D’Amico, Davide, Mottis, Adrienne, Potenza, Francesca, Sorrentino, Vincenzo, Li, Hao, Romani, Mario, Lemos, Vera, Schoonjans, Kristina +4 more·2019·Molecular Cell

Cited by (160)

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  20. Disruption of the Pum2 axis Aggravates neuronal damage following cerebral Ischemia-Reperfusion in mice
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  41. Additional file 1 of RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization
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  45. Additional file 8 of RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization
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  46. Additional file 9 of RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization
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  47. Additional file 5 of RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization
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  48. Additional file 2 of RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization
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  49. Additional file 6 of RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization
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  50. Additional file 3 of RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization
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  51. Additional file 4 of RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization
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  52. Additional file 7 of RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization
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  59. PAFAH1B1 stabilization, through PUM2-mediated competitive binding with miRNAs on its’ 3’-UTR, takes active actions on ferroptosis to overcome the radioresistance to 125I radioactive particles of pancreatic ductal adenocarcinoma
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