Nascent Pre-rRNA sorting via phase separation drives the assembly of dense fibrillar components in the human nucleolus
Yao, Run-Wen, Xu, Guang, Wang, Ying, Shan, Lin, Luan, Peng-Fei, Wang, Yang, Wu, Man, Yang, Liang-Zhong +3 more·2019·Molecular Cell
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- PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar IntegrityLina Zhu, Wenqin Wang, S H Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, H Q Liu, Kyoichi Isono et al. · 2026 · Advanced Science
- Nuclear condensates formed by truncated mutant NEK1s impede ribosomal RNA biogenesis and drive motor dysfunctionYixin Wang, Wen Hu, Rui Huang, Fanmin Wu, Haopeng Su, Jianye Zang, Xiaolei Huang, Yanli Liu, Haigang Ren, Jian Li et al. · 2026 · Nature Communications
- Pre-rRNA represses gene transcription in the XY body of male germ cellsLinlin Chen, Xiaochen Gai, Si Chen, Qilin Li, Yifan Sun, Peng Li, Chencheng Yao, Xiaochun Yu · 2026 · eLife
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- Inert polymer crowders drive phase separation of polyampholyte-like proteins by enhancing electrostatic correlationHaoke Zhou, Zongpei Wu, Shensheng Chen · 2026 · Physical review. E
- Molecular Grammar of Intrinsically Disordered Regions: How Sequence and Context Shape Biomolecular Condensation and DiseaseWei Liu, Sulin Lou · 2026 · Biomolecules
- NEAT1_1 -encoded microprotein PSNEAT1 drives rDNA transcription via phase separation with WRNXiwang Yang, Qiwei Chen, Ya Wen, Ao Ding, Xianting Huang, Liqiang Duan, Weihu Ma, Xueqing Zhao, Chang Zhang, Xuemei Jia et al. · 2026 · Proceedings of the National Academy of Sciences
- Nucleolar reorganization on stress depends on physicochemical changes due to reduced nascent rRNA synthesisSinjini Ghosh, Souvik Sen, Aprotim Mazumder · 2026 · EMBO Reports
- RNA ‐Protein Assemblies: A Review of Biophysical Principles and Coarse‐Grained Modeling ApproachesMuhammad Waleed Iqbal, Patrick R. Onck · 2026 · Wiley Interdisciplinary Reviews - RNA
- Phase separation and chromatinLannah S. Abasi, Galia T. Debelouchina · 2026 · Elsevier eBooks
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- Dynamic phosphorylation of TCOF1 controlled by CK2 and PPM1D regulates nucleolar condensation and RNA polymerase I activityNatálie Palková, Matous Palek, Marketa Brodinova, Zuzana Chalupova, Radka Storchova, Jana Jašprová, Pavel Talacko, Dušan Cmarko, Libor Macůrek · 2026 · Nucleic Acids Research