The DOI matches its Crossref record; 181 of the 181 references it cites were found in a registry or an index.
Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective
Open accessAbstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple organs. A complex interaction of genetics, environment, and hormones leads to immune dysregulation and breakdown of tolerance to self-antigens, resulting in autoantibody production, inflammation, and destruction of end-organs. Emerging evidence on the role of these factors has increased our knowledge of this complex disease, guiding therapeutic strategies and identifying putative biomarkers. Recent findings include the characterization of genetic/epigenetic factors linked to SLE, as well as cellular effectors. Novel observations have provided an improved understanding of the contribution of tissue-specific factors and associated damage, T and B lymphocytes, as well as innate immune cell subsets and their corresponding abnormalities. The intricate web of involved factors and pathways dictates the adoption of tailored therapeutic approaches to conquer this disease.
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2 retracted
Martinez, J., Malireddi, R. K. S., Lu, Q., Cunha, L. D., Pelletier, S., Gingras, S., Orchard, R., Guan, J.-L., Tan, H., Peng, J., et al. (2015) · Nature Cell Biology · doi:10.1038/ncb3192 · Cited by 758 · cited 1×
“Recently, a form of noncanonicalautophagywasdescribed,knownasmicrotubule-associatedprotein1A/1B-light chain 3 (LC3)-associated phagocytosis (LAP), in which phagosomes recruit elements of autophagy to facilitate the phagocytosis of dying cell debris [135].”
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RetractedThe 1982 revised criteria for the classification of systemic lupus erythematosus
Tan, E. M., Cohen, A. S., Fries, J. F., Masi, A. T., Mcshane, D. J., Rothfield, N. F., Schaller, J. G., Talal, N., & Winchester, R. J. (1982) · Arthritis & Rheumatism · doi:10.1002/art.1780251101 · Cited by 14,519
Neutrophil Extracellular Traps Kill Bacteria
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(2016) · Diagnostic Imaging: Brain · doi:10.1016/b978-0-323-37754-6.50094-4 · Cited by 3,990
Tsokos, G. C. (2011) · New England Journal of Medicine · doi:10.1056/nejmra1100359 · Cited by 2,736
Self-citationBaechler, E. C., Batliwalla, F. M., Karypis, G., Gaffney, P. M., Ortmann, W. A., Espe, K. J., Shark, K. B., Grande, W. J., Hughes, K. M., Kapur, V., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337679100 · Cited by 2,240
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Interferon and Granulopoiesis Signatures in Systemic Lupus Erythematosus Blood
Bennett, L., Palucka, A. K., Arce, E., Cantrell, V., Borvak, J., Banchereau, J., & Pascual, V. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20021553 · Cited by 1,958
Genetic and epigenetic fine mapping of causal autoimmune disease variants
Farh, K. K.-H., Marson, A., Zhu, J., Kleinewietfeld, M., Housley, W. J., Beik, S., Shoresh, N., Whitton, H., Ryan, R. J. H., Shishkin, A. A., et al. (2015) · Nature · doi:10.1038/nature13835 · Cited by 1,956
Cited by
Autoimmunity and organ damage in systemic lupus erythematosus
Tsokos, G. C. (2020) · Nature Immunology · doi:10.1038/s41590-020-0677-6 · Cited by 580
Self-citationSingle-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus
Perez, R. K., Gordon, M. G., Subramaniam, M., Kim, M. C., Hartoularos, G. C., Targ, S., Sun, Y., Ogorodnikov, A., Bueno, R., Lu, A., et al. (2022) · Science · doi:10.1126/science.abf1970 · Cited by 513
Mesenchymal stromal cell therapies: immunomodulatory properties and clinical progress
Wu, X., Jiang, J., Gu, Z., Zhang, J., Chen, Y., & Liu, X. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-01855-9 · Cited by 343
Zhao, M., Tan, Y., Peng, Q., Huang, C., Guo, Y., Liang, G., Zhu, B., Huang, Y., Liu, A., Wang, Z., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-02890-0 · Cited by 122
The Main Challenges in Systemic Lupus Erythematosus: Where Do We Stand?
Piga, M., & Arnaud, L. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10020243 · Cited by 99
Metadata
- Authors
- Moulton, V. R., Suarez-Fueyo, A., Meidan, E., Li, H., Mizui, M., & Tsokos, G. C.
- Venue
- Trends in Molecular Medicine
- Publisher
- Elsevier BV
- Published
- 2017-07
- Volume
- 23
- Issue
- 7
- Pages
- 615-635
- ISSN
- 1471-4914 (ISSN-L)
- OpenAlex
- W2625419804
- Cited by
- 469
- References
- 181
- FWCI
- 5.66
- Type
- journal article
- Language
- en
- Open access
- green
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- Moulton, V. R., Suarez-Fueyo, A., Meidan, E., Li, H., Mizui, M., & Tsokos, G. C. (2017). Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective. Trends in Molecular Medicine. https://doi.org/10.1016/j.molmed.2017.05.006
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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