Cerebrospinal fluid biomarkers as predictors of multiple sclerosis severity

Tolentino, Miguel; Pace, Francesca; Perantie, Dana C.; Mikesell, Robert; Huecker, Julia; Chahin, Salim; Ghezzi, Laura; Piccio, Laura; Cross, Anne H.

doi:10.1016/j.msard.2025.106268

Cerebrospinal fluid biomarkers as predictors of multiple sclerosis severity

Background Prognostic biomarkers at multiple sclerosis (MS) onset to predict disease severity may help guide initial therapy selection for people with MS. Over 20 disease-modifying treatments (DMTs) of varying levels of risk and efficacy now exist. The ability to predict MS severity would help to…