Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

Tomic, Jennifer L., Pensalfini, Anna, Head, Elizabeth, Glabe, Charles G.·2009·Neurobiology of Disease
DOI 10.1016/j.nbd.2009.05.024

Cited by (337)

Items 101–200 of 337

  1. The Role of Cholesterol Metabolism in Alzheimer’s Disease
    Sun, Jia-Hao, Yu, Jin-Tai, Tan, Lan · 2015 · Molecular Neurobiology
  2. Tenascin-C deficiency ameliorates Alzheimer's disease-related pathology in mice
    Kan Xie, Yang Liu, Wenlin Hao, Silke Walter, Botond Penke, Tobias Hartmann, Melitta Schachner, Klaus C Fassbender · 2013 · Neurobiology of Aging
  3. Sex differences in the association between apolipoprotein E ε4 allele and Alzheimer's disease markers
    Erin E. Sundermann, My Tran, Pauline M. Maki, Mark William Bondi, Alzheimer’s Disease Neuroimaging Initiative · 2018 · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
  4. Atomic resolution map of the soluble amyloid beta assembly toxic surfaces
    Rashik Ahmed, Michael Akcan, Adree Khondker, Maikel Christian Rheinstadter, José Carlos Bozelli, Richard M. Epand, Vincent A. Huynh, Ryan Gavin Wylie, Stephen Boulton, Jinfeng Huang et al. · 2019 · Chemical Science
  5. An Imaging and Systems Modeling Approach to Fibril Breakage Enables Prediction of Amyloid Behavior
    Wei‐Feng Xue, Sheena E. Radford · 2013 · Biophysical Journal
  6. Conjugated polymers for enhanced bioimaging
    Therése Klingstedt, K. Peter R. Nilsson · 2010 · Biochimica et Biophysica Acta (BBA) - General Subjects
  7. Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization
    Edmond Teng, Karen M. Taylor, Tina V. Bilousova, David A. Weiland, Thaidan Pham, Xiaohong Zuo, Fusheng Yang, Pingping Chen, Charles G. Glabe, Alison Takacs et al. · 2015 · Neurobiology of Disease
  8. Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse
    S H Kim, John Steele, Star W. Lee, Gregory Dane Clemenson, Tayler Carter, K Treuner, Reto A. Gadient, Pamela C. Wedel, Charles G. Glabe, Carrolee Barlow et al. · 2014 · Molecular Psychiatry
  9. Dogs with cognitive dysfunction syndrome: a natural model of Alzheimer's disease.
    Maria Neus Bosch, M. Pugliese, Javier Gimeno-Bayón, M. J. Rodríguez, N. Mahy · 2012 · Current Alzheimer Research
  10. A Fluorogenic AggTag Method Based on Halo‐ and SNAP‐Tags to Simultaneously Detect Aggregation of Two Proteins in Live Cells
    Kwan Ho Jung, Sojung F. Kim, Yu Liu, Xin Zhang · 2019 · ChemBioChem
  11. Blood Amyloid-β Oligomerization as a Biomarker of Alzheimer’s Disease: A Blinded Validation Study
    Young Chul Youn, Byoung Sub Lee, Gwang Je Kim, Ji Sun Ryu, Kuntaek Lim, Ryan Lee, Jeewon Suh, Young Ho Park, Jung‐Min Pyun, Nayoung Ryu et al. · 2020 · Journal of Alzheimer s Disease
  12. The Amyloid-Beta Clearance: From Molecular Targets to Glial and Neural Cells
    Wenjun Cai, Tong Wu, Ning Chen · 2023 · Biomolecules
  13. Association between increased levels of amyloid-β oligomers in plasma and episodic memory loss in Alzheimer’s disease
    Xue Wei Meng, Tao Li, Xiao Wang, Xiaozhen Lv, Zhiyu Sun, Jichun Zhang, Su Feng, Sungmin Kang, SangYun Kim, Seong Soo A. An et al. · 2019 · Alzheimer s Research & Therapy
  14. Amyotrophic lateral sclerosis pathogenesis: a journey through the secretory pathway
    Nassif, Melissa, Matus, Soledad, Castillo, Karen, Hetz, Claudio · 2010 · Antioxidants & Redox Signaling
  15. SOBA: Development and testing of a soluble oligomer binding assay for detection of amyloidogenic toxic oligomers
    Dylan W. Shea, Elizabeth A. Colasurdo, Alec S.T. Smith, Courtnie Jean Paschall, Suman Jayadev, Christopher Dirk Keene, Douglas R Galasko, Andrew Lin Ko, Ge Li, Elaine R. Peskind et al. · 2022 · Proceedings of the National Academy of Sciences
  16. Spinosin, a C-Glucosylflavone, from Zizyphus jujuba var. spinosa Ameliorates Aβ1–42 Oligomer-Induced Memory Impairment in Mice
    Sang Yoon Ko, Hyung Eun Lee, Se Jin Park, Se Jin Jeon, Boseong Kim, Qingtao Gao, Dae Sik Jang, Jong Hoon Ryu · 2015 · Biomolecules & Therapeutics
  17. AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly
    Sophie Sokolow, Kristen M. Henkins, Tina V. Bilousova, Carol A. Miller, Harry V. Vinters, Wayne W. Poon, Gregory M. Cole, Karen H. Gylys · 2011 · Neurobiology of Aging
  18. Antibody-based therapy in Alzheimer's disease
    Refik Pul, Richard C. Dodel, Martin Stangel · 2011 · Expert Opinion on Biological Therapy
  19. Plasma amyloid-β oligomers level is a biomarker for Alzheimer’s disease diagnosis
    L. Zhou, Koon Ho Chan, Leung‐Wing Chu, Jason Kwan, You‐Qiang Song, L.H. Chen, Philip Wing‐Lok Ho, Olivia Cheng, Jessica Wing-Man Ho, Karen S.L. Lam · 2012 · Biochemical and Biophysical Research Communications
  20. Iron and Alzheimer’s Disease: From Pathology to Imaging
    Dean Q. Tran, Phillip DiGiacomo, Donald E. Born, Marios Georgiadis, Michael Zeineh · 2022 · Frontiers in Human Neuroscience
  21. Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models
    Mariagioia Zampagni, Daniel Wright, Roberta Cascella, Giampiero D’Adamio, Fiorella Casamenti, Elisa Evangelisti, Francesca Cardona, Andrea Goti, Benedetta Nacmias, Sandro Sorbi et al. · 2012 · Free Radical Biology and Medicine
  22. Conformation-specific antibodies to target amyloid β oligomers and their application to immunotherapy for Alzheimer’s disease
    Kazuma Murakami · 2014 · Bioscience Biotechnology and Biochemistry
  23. Association of TDP-43 proteinopathy, cerebral amyloid angiopathy, and Lewy bodies with cognitive impairment in individuals with or without Alzheimer’s disease neuropathology
    David X. Thomas, Sumali Bajaj, Kevin McRae‐McKee, Christoforos Hadjichrysanthou, Roy Malcolm Anderson, John Collinge · 2020 · Scientific Reports
  24. Clusterin Associates Specifically with <scp>A</scp>β40 in <scp>A</scp>lzheimer's Disease Brain Tissue
    Howlett, David R., Hortobágyi, Tibor, Francis, Paul T. · 2013 · Brain Pathology
  25. Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation
    Luka Kulic, Jordan McAfoose, Tobias Welt, Christian Tackenberg, Claudia B. Späni, Fabian Wirth, Verena H. Finder, Uwe Konietzko, M Giese, Anne Eckert et al. · 2012 · Translational Psychiatry
  26. MER5101, a Novel Aβ1-15:DT Conjugate Vaccine, Generates a Robust Anti-Aβ Antibody Response and Attenuates Aβ Pathology and Cognitive Deficits in APPswe/PS1ΔE9 Transgenic Mice
    Bin Liu, Jeffrey L. Frost, Jing Sun, Hongjun Fu, Stephen Grimes, Peter Blackburn, Cynthia Ann Lemere · 2013 · Journal of Neuroscience
  27. Alzheimer's Therapeutics: Translation of Preclinical Science to Clinical Drug Development
    Alena V. Savonenko, Tatiana Melnikova, Andrew Hiatt, Tong Li, Paul F. Worley, Juan Carlos Troncoso, Phil C Wong, Don L Price · 2011 · Neuropsychopharmacology
  28. Bioactive human Alzheimer brain soluble Aβ: pathophysiology and therapeutic opportunities
    Shaomin Li, Andrew M. Stern · 2022 · Molecular Psychiatry
  29. Connectivity of Pathology: The Olfactory System as a Model for Network-Driven Mechanisms of Alzheimer’s Disease Pathogenesis
    Katherine H. Franks, Meng Inn Chuah, Anna Elizabeth King, James Clement Vickers · 2015 · Frontiers in Aging Neuroscience
  30. Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes
    Elysse M. Knight, Soong Ho Kim, Jessica Kottwitz, Asa Hatami, Ricardo Albay, Akinobu Z. Suzuki, Alex L. Lublin, Cristina M. Alberini, William L. Klein, Paul Szabo et al. · 2016 · Neurology Neuroimmunology & Neuroinflammation
  31. Differential contribution of isoaspartate post-translational modifications to the fibrillization and toxic properties of amyloid β and the Asn23 Iowa mutation
    Silvia Fossati, Krysti L. Todd, Krystal Sotolongo, Jorge A. Ghiso, Agueda A. Rostagno · 2013 · Biochemical Journal
  32. Despite its role in assembly, methionine 35 is not necessary for amyloid β‐protein toxicity
    Panchanan Maiti, Aleksey Lomakin, George B. Benedek, Gal Bitan · 2010 · Journal of Neurochemistry
  33. Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers
    Heledd Jarosz-Griffiths, Nicola J. Corbett, Helen A. Rowland, Kate Fisher, Alys C. Jones, Jennifer Baron, Gareth J. Howell, Sally A. Cowley, Satyan Chintawar, M. Zameel Cader et al. · 2019 · Journal of Biological Chemistry
  34. Neuroligin-1 is altered in the hippocampus of Alzheimer’s disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers
    Julien Dufort‐Gervais, Chloé Provost, Laurence Charbonneau, Christopher Mark Norris, Frédéric Calon, Valérie Mongrain, Jonathan Brouillette · 2020 · Scientific Reports
  35. β-amyloid: The known unknowns
    Ayton, Scott, Bush, Ashley I. · 2021 · Ageing Research Reviews
  36. Effect of Synthetic Aβ Peptide Oligomers and Fluorinated Solvents on Kv1.3 Channel Properties and Membrane Conductance
    Maria Lioudyno, Matteo Broccio, Yuri Sokolov, Suhail Rasool, Jessica Wu, Michael T. Alkire, Virginia Liu, J. Ashot Kozak, Philip R. Dennison, Charles G. Glabe et al. · 2012 · PLoS ONE
  37. A Generic Method for Design of Oligomer-Specific Antibodies
    Kristoffer Brännström, Malin Lindhagen‐Persson, Anna L. Gharibyan, Irina Iakovleva, Monika Vestling, Mikael E. Sellin, Thomas Brännström, Ludmilla A. Morozova‐Roche, Lars Forsgren, Anders Olofsson · 2014 · PLoS ONE
  38. The dynamic mechanism of presenilin-1 function: Sensitive gate dynamics and loop unplugging control protein access
    Arun Kumar Somavarapu, Kasper P. Kepp · 2016 · Neurobiology of Disease
  39. Expression in Drosophila of Tandem Amyloid β Peptides Provides Insights into Links between Aggregation and Neurotoxicity
    Elena Speretta, Thomas Robert Jahn, Gian Gaetano Tartaglia, Giorgio Favrin, Teresa Pereira de Barros, Sara Imarisio, David A. Lomas, Leila M. Luheshi, Damian C. Crowther, Christopher Martin Dobson · 2012 · Journal of Biological Chemistry
  40. The central molecular clock is robust in the face of behavioural arrhythmia in aDrosophilamodel of Alzheimer's disease
    Ko‐Fan Chen, Bernard P. Possidente, David A. Lomas, Damian C. Crowther · 2014 · Disease Models & Mechanisms
  41. Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer’s Disease
    Arjun Thapa, Eva Y. Chi · 2015 · Advances in experimental medicine and biology
  42. Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane
    Mariagioia Zampagni, Elisa Evangelisti, Roberta Cascella, Gianfranco Liguri, Matteo Becatti, Anna Pensalfini, Daniela Letizia Uberti, Giovanna Cenini, Maurizio Memo, Silvia Bagnoli et al. · 2010 · Journal of Molecular Medicine
  43. In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology
    Laura Trujillo‐Estrada, Sebastián Jiménez, Vanessa De Castro, M. Torres, David Baglietto‐Vargas, Inés Moreno‐González, Victoria Navarro, Raquel Maria Sanchez-Varo, Elisabeth Sánchez‐Mejías, José Carlos Dávila et al. · 2013 · Acta Neuropathologica Communications
  44. A Strategy for Designing a Peptide Probe for Detection of β‐Amyloid Oligomers
    Yang Hu, Baihao Su, Chung‐Sei Kim, Michael X. Hernandez, Agueda A. Rostagno, Jorge A. Ghiso, Jin Ryoun Kim · 2010 · ChemBioChem
  45. Prevention approaches in a preclinical canine model of Alzheimer’s disease: benefits and challenges
    Paulina R. Davis, Elizabeth Head · 2014 · Frontiers in Pharmacology
  46. Oxidative Stress and Protein Quality Control Systems in the Aged Canine Brain as a Model for Human Neurodegenerative Disorders
    Mariarita Romanucci, Leonardo Della Salda · 2015 · Oxidative Medicine and Cellular Longevity
  47. A Universal Method for Detection of Amyloidogenic Misfolded Proteins
    Alice Yen-Wen Yam, Xuemei Wang, Carol Man Gao, Michael D. Connolly, Ronald N. Zuckermann, Thieu Bleu, John Hall, Joseph P. Fedynyshyn, Sophie Allauzen, David Peretz et al. · 2011 · Biochemistry
  48. Amyloid-Beta Peptide 1-42 Causes Microtubule Deregulation through N-methyl-D-aspartate Receptors in Mature Hippocampal Cultures
    Sandra Isabel Mota, Ildete L. Ferreira, Cláudia Pereira, Catarina Resende Oliveira, Ana Cristina Rego · 2012 · Current Alzheimer Research
  49. “What Doesn’t Kill You Makes You Stronger”: Future Applications of Amyloid Aggregates in Biomedicine
    Sherin Abdelrahman, Mawadda Alghrably, Joanna Izabela Lachowicz, Abdul-Hamid M. Emwas, Charlotte A. E. Hauser, Mariusz Jaremko · 2020 · Molecules
  50. Tailoring the Antibody Response to Aggregated Aß Using Novel Alzheimer-Vaccines
    Markus Mandler, Radmila Santic, Petra Gruber, Yeliz Cinar, Dagmar Pichler, Susanne Aileen Funke, Dieter Willbold, Achim Schneeberger, WALTER A. SCHMIDT, Frank Mattner · 2015 · PLoS ONE
  51. Single Molecule Tracking Analysis Reveals That the Surface Mobility of Amyloid Oligomers Is Driven by Their Conformational Structure
    Martino Calamai, Francesco Saverio Pavone · 2011 · Journal of the American Chemical Society
  52. Does the difference between PART and Alzheimer’s disease lie in the age-related changes in cerebral arteries that trigger the accumulation of Aβ and propagation of tau?
    Roy O. Weller, Cheryl A. Hawkes, Roxana Octavia Carare, John Hardy · 2015 · Acta Neuropathologica
  53. Asiaticoside ameliorates β-amyloid-induced learning and memory deficits in rats by inhibiting mitochondrial apoptosis and reducing inflammatory factors
    Zhuo Zhang, Xiaobin Li, Duo Li, Mao Luo, Yongjie Li, Song Li, Xian Jiang · 2016 · Experimental and Therapeutic Medicine
  54. Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules
    Emily Mitchell Sontag, Gregor P. Lotz, Guocheng Yang, Christopher J. Sontag, Brian J Cummings, Charles G. Glabe, Paul J. Muchowski, Leslie Michels Thompson · 2012 · Journal of Huntington s Disease
  55. Impaired hippocampal acetylcholine release parallels spatial memory deficits in Tg2576 mice subjected to basal forebrain cholinergic degeneration
    Bettina Laursen, Arne Mørk, Niels Plath, Uffe Kristiansen, Jesper F. Bastlund · 2013 · Brain Research
  56. Inhibition of poly(ADP-ribose) polymerase-1 alters expression of mitochondria-related genes in PC12 cells: relevance to mitochondrial homeostasis in neurodegenerative disorders
    Grzegorz Arkadiusz Czapski, Magdalena Cieślik, Przemysław Leonard Wencel, Sylwia Wójtowicz, Robert Piotr Strosznajder, Joanna Benigna Strosznajder · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  57. Specificity and sensitivity of the Abeta oligomer ELISA
    Andrea C. Klaver, Lynnae M. Patrias, John M. Finke, David A. Loeffler · 2010 · Journal of Neuroscience Methods
  58. Assessing β-Amyloid-Induced NLRP3 Inflammasome Activation in Primary Microglia
    Mareike Schnaars, Hannes Beckert, Annett Halle · 2013 · Methods in molecular biology
  59. Disruption of Amyloid Plaques Integrity Affects the Soluble Oligomers Content from Alzheimer Disease Brains
    Sebastián Jiménez, Victoria Navarro, Javier Moyano, Maria Virtudes Sanchez-Mico, M. Torres, José Carlos Dávila, Marisa Vizuete, Antonia Gutiérrez, Javier Vitórica · 2014 · PLoS ONE
  60. Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease
    Qiu‐Lan Ma, Edmond Teng, Xiaohong Zuo, Mychica R. Jones, Bruce Teter, Evan Y. Zhao, Cansheng Zhu, Tina V. Bilousova, Karen H. Gylys, Liana G. Apostolova et al. · 2018 · Neurobiology of Disease
  61. Total flavonoid extract from Dracoephalum moldavica L. attenuates β-amyloid-induced toxicity through anti-amyloidogenesic and neurotrophic pathways
    Qingshan Liu, Hailun Jiang, Yu Wang, Linlin Wang, Junxia Zhang, Chenghui He, Shuai Shao, Tiantai Zhang, Jianguo Xing, Rui Liu · 2017 · Life Sciences
  62. The isotropic fractionator provides evidence for differential loss of hippocampal neurons in two mouse models of Alzheimer’s disease
    Brautigam, Hannah, Steele, John W, Westaway, David, Fraser, Paul E, George-Hyslop, Peter H St, Gandy, Sam, Hof, Patrick R, Dickstein, Dara L · 2012 · Molecular Neurodegeneration
  63. Production of an anti-Aβ antibody fragment in Pichia pastoris and in vitro and in vivo validation of its therapeutic effect
    Laia Montoliu‐Gaya, Gisela Esquerda-Canals, Sílvia Bronsoms, Sandra Villegas · 2017 · PLoS ONE
  64. Emerging Alzheimer’s disease therapeutics: promising insights from lipid metabolism and microglia-focused interventions
    Nour S. Tobeh, Kimberley D. Bruce · 2023 · Frontiers in Aging Neuroscience
  65. Alzheimer's Disease: The Quest to Understand Complexity
    S. Marques, Catarina R. Oliveira, T. Outeiro, C. Pereira · 2010 · Journal of Alzheimer's Disease
  66. Pathological Hallmarks, Clinical Parallels, and Value for Drug Testing in Alzheimer's Disease of the APP[V717I] London Transgenic Mouse Model
    An Tanghe, Annelies Termont, Pascal Merchiers, Stephan Schilling, Hans‐Ulrich Demuth, Louise A. Scrocchi, Fred VAN LEUVEN, Gerard Griffioen, Tom Van Dooren · 2010 · International Journal of Alzheimer s Disease
  67. Operational dissection of β‐amyloid cytopathic effects on cultured neurons
    Noëlle Callizot, Maud Combes, Rémy Steinschneider, Philippe Poindron · 2013 · Journal of Neuroscience Research
  68. Brain Aging and Late-Onset Alzheimer’s Disease: A Matter of Increased Amyloid or Reduced Energy?
    Patrizia Mecocci, Marta Baroni, Umberto Senin, Virginia Boccardi · 2018 · Journal of Alzheimer s Disease
  69. Interactions of amyloid-β peptides on lipid bilayer studied by single molecule imaging and tracking
    Chun‐Chieh Chang, Elin Edwald, Sarah L. Veatch, Duncan G. Steel, Ari Gafni · 2018 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  70. A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ 42 and tau‐induced pathophysiological effects on long‐term potentiation
    Julbert Caneus, Nesar Akanda, John W. Rumsey, Xiufang Guo, Max Jackson, Christopher J. Long, Frank Sommerhage, Sanya Georgieva, Nicholas M. Kanaan, David Morgan et al. · 2020 · Alzheimer s & Dementia Translational Research & Clinical Interventions
  71. A new kid in the folding funnel: Molecular chaperone activities of the BRICHOS domain
    Axel Leppert, Helen Poska, Michael Landreh, Axel Abelein, Gefei Chen, Jan Johansson · 2023 · Protein Science
  72. Body fluid biomarkers in Alzheimer's disease.
    Huan Lu, Xi‐Chen Zhu, Teng Jiang, Jin‐Tai Yu, Lan Tan · 2015 · PubMed Central
  73. Autoreactive‐Aβ antibodies promote APP β‐secretase processing
    Juan Deng, Huayan Hou, Brian N. Giunta, Takashi Mori, Yan‐Jiang Wang, Frank Fernandez, Sascha Weggen, Wataru Araki, Demian F. Obregon, Jun Tan · 2011 · Journal of Neurochemistry
  74. The elusive nature and diagnostics of misfolded Aβ oligomers
    Eleonora Cerasoli, Maxim G. Ryadnov, Brian Austen · 2015 · Frontiers in Chemistry
  75. Synergistic Interactions between Alzheimer’s Aβ40 and Aβ42 on the Surface of Primary Neurons Revealed by Single Molecule Microscopy
    Chun-Chieh Chang, J. Christian Althaus, Cynthia J. L. Carruthers, Michael A. Sutton, Duncan G. Steel, Ari Gafni · 2013 · PLoS ONE
  76. Accumulation of cellular prion protein within β‐amyloid oligomer plaques in aged human brains
    Reisuke H. Takahashi, Mayumi Yokotsuka, Minoru Tobiume, Yuko Sato, Hideki Hasegawa, Toshitaka Nagao, Gunnar K. Gouras · 2021 · Brain Pathology
  77. Diverse therapeutic potential of 3-hydroxy-4-pyranones and related compounds as kojic acid analogs
    Saeed Emami, Reza Ahmadi, Hamideh Ahadi, Morteza Ashooriha · 2022 · Medicinal Chemistry Research
  78. Potential Novel Approaches to Understand the Pathogenesis and Treat Alzheimer’s Disease
    Eleanor Drummond, Fernando Goñi, Shan Liu, Frances Prelli, Henrieta Scholtzova, Thomas Wısnıewskı · 2018 · Journal of Alzheimer s Disease
  79. Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer’s APP/PSEN1 mice by gene targeting of diabetes/Alzheimer’s-related Sorcs1
    Elysse M. Knight, Henry H. Ruiz, Soong Ho Kim, Jessica C. Harte, Wilson Hsieh, Charles G. Glabe, William L. Klein, Alan Attie, Christoph Buettner, Michelle E. Ehrlich et al. · 2016 · Acta Neuropathologica Communications
  80. Chinese Herbal Medicine Xueshuantong Enhances Cerebral Blood Flow and Improves Neural Functions in Alzheimer’s Disease Mice
    Yangmei Huang, Baihong Guo, Bihua Shi, Qingtao Gao, Qiang Zhou · 2018 · Journal of Alzheimer s Disease
  81. Riluzole ameliorates soluble Aβ1–42-induced impairments in spatial memory by modulating the glutamatergic/GABAergic balance in the dentate gyrus
    Yang Yang, Wei-gang Ji, Yingjie Zhang, Liping Zhou, Hao Chen, Nian Yang, Zhi-ru Zhu · 2020 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  82. Designed Trpzip-3 β-Hairpin Inhibits Amyloid Formation in Two Different Amyloid Systems
    Gene Hopping, Jackson Kellock, Byron W. Caughey, Valerie Daggett · 2013 · ACS Medicinal Chemistry Letters
  83. Kinetic and structural characterization of amyloid‐β peptide hydrolysis by human angiotensin‐1‐converting enzyme
    Kate Larmuth, Geoffrey Masuyer, Ross G. Douglas, Sylva L. U. Schwager, K. Ravi Acharya, Edward D. Sturrock · 2016 · FEBS Journal
  84. A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice
    Armine Hovakimyan, Tatevik Antonyan, Sepideh Kiani Shabestari, Olga Svystun, Gor Chailyan, Morgan Coburn, William Carlen-Jones, Irina Petrushina, Jean Paul Chadarevian, Karen Zagorski et al. · 2019 · Scientific Reports
  85. The calcium-sensing receptor: A novel Alzheimer's disease crucial target?
    Ubaldo Armato, Clara Bonafini, Balu Chakravarthy, Raffaella Pacchiana, Anna Chiarini, James F. Whitfield, Ilaria Dal Prà · 2012 · Journal of the Neurological Sciences
  86. Preventive immunization of aged and juvenile non-human primates to beta-amyloid
    Julia Kofler, Brian J. Lopresti, Christopher Janssen, Anita M. Trichel, Eliezer Masliah, Olivera J. Finn, Russell D. Salter, GEOFFREY H. MURDOCH, Chester A. Mathis, Clayton A. Wiley · 2012 · Journal of Neuroinflammation
  87. Early Amyloidogenic Oligomerization Studied through Fluorescence Lifetime Correlation Spectroscopy
    J. M. Paredes, S. Casares, M. Ruedas-Rama, E. Fernández, F. Castello, Lorena Varela, Á. Orte · 2012 · International Journal of Molecular Sciences
  88. The Relationship between Aggregation and Toxicity of Polyglutamine-Containing Ataxin-3 in the Intracellular Environment of Escherichia coli
    Gaetano Invernizzi, Francesco A. Aprile, Antonino Natalello, Andrea Ghisleni, Amanda Penco, Annalisa Relini, Silvia Maria Doglia, Paolo Tortora, Maria Elena Regonesi · 2012 · PLoS ONE
  89. Immunotherapy to improve cognition and reduce pathological species in an Alzheimer’s disease mouse model
    Krystal Herline, Frances Prelli, Pankaj D Mehta, Claire MacMurray, Fernando Goñi, Thomas Wısnıewskı · 2018 · Alzheimer s Research & Therapy
  90. Alzheimer disease: update on basic mechanisms.
    Xiaoning Bi · 2010 · PubMed
  91. Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry
    Aneika C. Leney, Clare L. Pashley, Charlotte A. Scarff, Sheena E. Radford, Alison E. Ashcroft · 2013 · Molecular BioSystems
  92. Selenomethionine Attenuates the Amyloid-β Level by Both Inhibiting Amyloid-β Production and Modulating Autophagy in Neuron-2a/AβPPswe Cells
    Zhong-Hao Zhang, Qiuyan Wu, Chen Chen, Rui Zheng, Yao Chen, Qiong Liu, Jiazuan Ni, Guo-Li Song · 2017 · Journal of Alzheimer s Disease
  93. Distinctive temporal profiles of detergent-soluble and -insoluble tau and Aβ species in human Alzheimer’s disease
    David J. Koss, Marina Dubini, Heather M. Buchanan, Claire E. Hull, Bettina Platt · 2018 · Brain Research
  94. Protein structures in Alzheimer's disease: The basis for rationale therapeutic design
    Laia Montoliu‐Gaya, Sandra Villegas · 2015 · Archives of Biochemistry and Biophysics
  95. Pathology of nNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer’s Disease
    Seungho Choi, Je‐Seong Won, Steven Lewis Carroll, Balasubramaniam Annamalai, Inderjit Singh, Avtar Kaur Singh · 2018 · Neuroscience
  96. Antibody against Small Aggregated Peptide Specifically Recognizes Toxic Aβ-42 Oligomers in Alzheimer’s Disease
    Riddhi U. Bodani, Urmi Sengupta, Diana Laura Castillo‐Carranza, Marcos Jair Guerrero‐Munoz, Julia E. Gerson, Jai S. Rudra, Rakez Kayed · 2015 · ACS Chemical Neuroscience
  97. N-terminal Domain of Prion Protein Directs Its Oligomeric Association
    Clare R. Trevitt, Laszlo L. P. Hosszu, Mark Batchelor, Silvia Panico, Cassandra Terry, Andrew J. Nicoll, Emmanuel Risse, William A. Taylor, Malin K. Sandberg, Huda Al-Doujaily et al. · 2014 · Journal of Biological Chemistry
  98. Alzheimer’s disease: An exacerbation of senile phenoptosis
    Н. К. Исаев, Elena V. Stelmashook, Е. Е. Генрихс, М.В. Оборина, Капкаева Марина Рафаилевна, Vladimir P. Skulachev · 2015 · Biochemistry (Moscow)
  99. Anti-β-sheet conformation monoclonal antibody reduces tau and Aβ oligomer pathology in an Alzheimer’s disease model
    Fernando Goñi, Mitchell Martá-Ariza, Krystal Herline, Daniel Kevin Peyser, Allal Boutajangout, Pankaj D Mehta, Eleanor Drummond, Frances C. Prelli, Thomas Wısnıewskı · 2018 · Alzheimer s Research & Therapy
  100. Kinetic Transition in Amyloid Assembly as a Screening Assay for Oligomer-Selective Dyes
    Jeremy Barton, D. Sebastian Arias, Chamani Niyangoda, Gustavo J. Borjas, Nathan Le, Saefallah Mohamed, Martin Muschol · 2019 · Biomolecules