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Cited by 253

The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.

Risk factors for posttraumatic stress disorder: An umbrella review of systematic reviews and meta-analyses

Tortella-Feliu, Miquel, Fullana, Miquel A., Pérez-Vigil, Ana, Torres, Xavier, Chamorro, Jacobo, Littarelli, Sergio A., Solanes, Aleix, Ramella-Cravaro, Valentina, Vilar, Ana, González-Parra, José A., Andero, Raül, Reichenberg, Abraham, Mataix-Cols, David, Vieta, Eduard, Fusar-Poli, Paolo, Ioannidis, John P.A., Stein, Murray B., Radua, Joaquim, Fernández de la Cruz, Lorena·2019·Neuroscience & Biobehavioral Reviews

Abstract

Approximately one third of individuals who experience a severe traumatic event will develop posttraumatic stress disorder (PTSD). It is crucial to identify what factors may be associated with increased or decreased risk for PTSD. We conducted an umbrella review of systematic reviews and meta-analyses of risk/protective factors for PTSD and assessed and graded the evidence of the association between each factor and PTSD. Thirty-three systematic reviews and meta-analyses were included and 130 potential risk factors were identified. Of those, 57 showed a significant association with PTSD. Being female or being indigenous people of the Americas, among the sociodemographic factors; history of physical disease and family history of psychiatric disorder, among the pretrauma factors; and cumulative exposure to potentially traumatic experiences, trauma severity, and being trapped during an earthquake, among the peritrauma factors, showed convincing or highly suggestive evidence of an association with PTSD. Data from prospective studies were less conclusive. Our results have the potential of helping refine PTSD prediction models and contributing to the design of prevention strategies.

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Metadata

Authors
Tortella-Feliu, M., Fullana, M. A., Pérez-Vigil, A., Torres, X., Chamorro, J., Littarelli, S. A., Solanes, A., Ramella-Cravaro, V., Vilar, A., González-Parra, J. A., Andero, R., Reichenberg, A., Mataix-Cols, D., Vieta, E., Fusar-Poli, P., Ioannidis, J. P. A., Stein, M. B., Radua, J., & Fernández de la Cruz, L.
Venue
Neuroscience & Biobehavioral Reviews
Publisher
Elsevier BV
Published
2019-12
Volume
107
Pages
154-165
ISSN
0149-7634 (ISSN-L)
OpenAlex
W2973089156
Cited by
253
References
65
FWCI
3.40
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Risk factors for posttraumatic stress disorder: An umbrella review of systematic reviews and meta-analyses. https://app.cochat.ai/papers/10.1016/j.neubiorev.2019.09.013
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Tortella-Feliu, M., Fullana, M. A., Pérez-Vigil, A., Torres, X., Chamorro, J., Littarelli, S. A., Solanes, A., Ramella-Cravaro, V., Vilar, A., González-Parra, J. A., Andero, R., Reichenberg, A., Mataix-Cols, D., Vieta, E., Fusar-Poli, P., Ioannidis, J. P. A., Stein, M. B., Radua, J., & Fernández de la Cruz, L. (2019). Risk factors for posttraumatic stress disorder: An umbrella review of systematic reviews and meta-analyses. Neuroscience & Biobehavioral Reviews. https://doi.org/10.1016/j.neubiorev.2019.09.013

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.