Cited by 90Neuroscience and Neural EngineeringTactile and Sensory InteractionsPain Management and Treatment

Artificial vision through neuronal stimulation

Fernandes, Rodrigo A. Brant, Diniz, Bruno, Ribeiro, Ramiro, Humayun, Mark·2012·Neuroscience Letters

Abstract

Introduction The term visual prosthesis refers to any device capable of eliciting visual percepts in an individual through electrical stimulation of any part of the visual system.Background Blindness can be due to eye pathology or due to damage of the lateral geniculate or visual cortex. Eye pathology other than diseases that affect the cornea and lens are numerous and some of the leading causes are diabetic retinopathy, age-related macular degeneration, retinal detachment, glaucoma, and retinal vascular occlusions. The visual prosthesis can be divided into non-retinal and retinal approaches. Non-retinal approaches include cortical and optic nerve prosthesis. Retinal approaches are aimed at eye pathologies in which at least part of the optic nerve remains intact whereas when the optic nerve is nearly completely damaged and/or the eye itself is disfigured or degenerated then a non-retinal approach is warranted. The retinal prosthesis can be placed on the surface of the retina, in the subretinal space or in the suprachoroidal space.Results Several independent groups related variable degrees of success in promoting visual sensations through electrical stimulation of the visual system. Every technique, equipment and anatomical target has its advantages and disadvantages, and the biological/electrical-mechanical interface is still the aspect of the research towards a chronic, long term, reliable biomimetic implant.Conclusions The visual prostheses have achieved significant developments in recent years. We see continued improvement in visual acuity with increasing number and density of electrodes. Even though the visual acuity is still poor relative to normal vision, these subjects can read letters using their implants. Perhaps more importantly, blind patients can use these devices for mobility and orientation.

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Crossref · 10.1016/j.neulet.2012.01.063

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  • The complexity of the visual cortex with neurons specifically tuned for specific cues could hinder the ability to evoke simple uniformly shaped phosphenes.

    “On the other hand, the complexity of the visual cortex with neurons specifically tuned for specific cues [95] could hinder the ability to evoke simple uniformly shaped phosphenes.”

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References 58 · Cited by 90

Authors
Fernandes, R. A. B., Diniz, B., Ribeiro, R., & Humayun, M.
Affiliations
University of Southern California (US)
Venue
Neuroscience Letters
Publisher
Elsevier BV
Published
2012-06
Volume
519
Issue
2
Pages
122-128
ISSN
0304-3940 (ISSN-L)
OpenAlex
W2026096187
Cited by
90
References
58
Citations by year
2025: 2 · 2023: 2 · 2022: 4 · 2021: 22 · 2020: 3 · 2019: 5 · 2018: 7 · 2017: 10 · 2016: 12 · 2015: 5 · 2014: 12 · 2013: 4 · 2012: 1
FWCI
0.75
Type
journal article
Language
en
Open access
closed
Locations
  • Neuroscience Letters (publishedVersion)
  • PubMed (publishedVersion)
  • UNIFESP Institutional Repository (Universidade Federal de São Paulo) (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
Keywords
visual prosthesis, retinal prosthesis, blindness, retinal degeneration, visual acuity, electrode density, biomimetic implants, visual perception
MeSH terms
Blindness, Electric Stimulation Therapy, Humans, Neurons, Visual Prosthesis

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