Association of angiotensin-converting enzyme functional gene I/D polymorphism with amnestic mild cognitive impairment

Zhang, Zhengsheng; Deng, Linglong; Yu, Hui; Shi, Yongmei; Bai, Feng; Xie, Chunming; Yuan, Yonggui; Jia, Jianping; Zhang, Zhijun

doi:10.1016/j.neulet.2012.02.074

Association of angiotensin-converting enzyme functional gene I/D polymorphism with amnestic mild cognitive impairment

The relationship between angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and serum ACE activity, as well as amnestic mild cognitive impairment (aMCI), was investigated. The study recruited 90 aMCI patients and 90 matched healthy controls. All subjects underwent an e…