The effects of long-term sleep deprivation on the long-term potentiation in the dentate gyrus and brain oxidation status in rats

Some evidence suggests that sleep deprivation might impair synaptic plasticity and produce oxidative stress in the hippocampus. However it is not clear whether impairment of long-term potentiation depends on the oxidative stress evoked by sleep deprivation protocol. In this study we aimed to inve…