Fiber tractography using machine learning
Open accessPublished version of a preprint
Abstract
We present a fiber tractography approach based on a random forest classification and voting process, guiding each step of the streamline progression by directly processing raw diffusion-weighted signal intensities. For comparison to the state-of-the-art, i.e. tractography pipelines that rely on mathematical modeling, we performed a quantitative and qualitative evaluation with multiple phantom and in vivo experiments, including a comparison to the 96 submissions of the ISMRM tractography challenge 2015. The results demonstrate the vast potential of machine learning for fiber tractography.
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Recent advances in machine-learning-driven tractography show great potential in improving the specificity of tractograms.
“Recent advances in machine-learning-driven tractography also show great potential in improving the specificity of tractograms59, 60.”
From Tractography-based connectomes are dominated by false-positive connections (2016) · cites this paper as [60]
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References 70 · Cited by 68
Research works printed but not linked: 2
- Basser, P.J., 1998. Fiber-tractography via diffusion tensor MRI, in: Proc. International Society for Magnetic Resonance in Medicine.
- Götz, Michael, Weber, Christian, Stieltjes, Bram, Maier-Hein, K.H., 2014. Learning from Small Amounts of Labeled Data in a Brain Tumor Classification Task, in: Second Workshop on Transfer and Multi-Task Learning: Theory Meets Practice, Neural Information Processing Systems (NIPS). Montreal, Canada.
- Authors
- Neher, P. F., Côté, M.-A., Houde, J.-C., Descoteaux, M., & Maier-Hein, K. H.
- Affiliations
- German Cancer Research Center (DE)
- Université de Sherbrooke (CA)
- Corresponding author
- Neher, Peter F.
- ORCID
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2017-09
- Volume
- 158
- Pages
- 417-429
- ISSN
- 1053-8119 (ISSN-L)
- OpenAlex
- W2951290748
- Cited by
- 68
- References
- 70
- Citations by year
- 2026: 6 · 2025: 12 · 2024: 6 · 2023: 2 · 2022: 7 · 2021: 10 · 2020: 12 · 2019: 4 · 2018: 7 · 2017: 2
- FWCI
- 5.26
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Locations
- NeuroImage (publishedVersion)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion)
- PubMed (publishedVersion)
- Funders
- 16 NIH Institutes and Centers
- McDonnell Center
- Collaborative Research Center (SFB/TRR 125)
- German Research Foundation (INST 35/1120-1)
- DFG (MA 6340/10-1, MA 6340/12-1)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
- Keywords
- fiber tractography, diffusion MRI, random forest, machine learning, white matter fiber tracking
- MeSH terms
- Machine Learning, Brain Mapping, Humans, Diffusion Tensor Imaging
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