Altered Cortical Synaptic Morphology and Impaired Memory Consolidation in Forebrain- Specific Dominant-Negative PAK Transgenic Mice

Hayashi, Mansuo L, Choi, Se-Young, Rao, B.S.Shankaranarayana, Jung, Hae-Yoon, Lee, Hey-Kyoung, Zhang, Dawei, Chattarji, Sumantra, Kirkwood, Alfredo +1 more·2004·Neuron

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Items 201–280 of 280

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  10. The molecular and cellular basis of memory engrams: Mechanisms of synaptic and systems consolidation
    Janina Kupke, Ana M.M. Oliveira · 2025 · Neurobiology of Learning and Memory
  11. Steady‐state increase of cAMP‐response element binding protein, Rac, and PAK signaling in presenilin‐deficient neurons
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  12. Cytoskeletal changes in diseases of the nervous system
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  18. Disruption of PAK3 Signaling in Social Interaction Induced cFos Positive Cells Impairs Social Recognition Memory
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  20. Grading Gradients: Evaluating Evidence for Time-dependent Memory Reorganization in Experimental Animals
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  30. X-Linked ASDs and ID Gene Mutations
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  34. Role of Central Insulin-Like Growth Factor-1 Receptor Signalling in Ageing and Endocrine Regulation
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  37. Molecular Mechanisms of Dendritic Spine Plasticity in Development and Aging
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  38. Learning-induced enduring changes in inhibitory synaptic transmission in lateral amygdala are mediated by p21-activated kinase
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  40. Expressionsanalyse des murinen alphaPix/Arhgef6-Proteins und funktionelle Charakterisierung der alphaPix/Arhgef6-Knockout-Maus
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  41. Spine Morphology and Plasticity in X-linked Mental Retardations
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  43. Connecting the Dots
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  44. Synaptic Abnormalities and Neuroplasticity
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  45. Cyclin-Dependent Kinase 5 (Cdk5): Linking Synaptic Plasticity and Neurodegeneration
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  46. PAK1 in Alzheimer’s and Huntington’s Diseases
    Qiu‐Lan Ma, Fusheng Yang, Sally Ann Frautschy, Greg M. Cole · 2013 · Elsevier eBooks
  47. Distinct Roles of the Rho-GTPase Associated Kinases PAK and ROCK in the Regulation of Dendritic Spines and Synaptic Plasticity
    Suhail Asrar, Zhengping Jia · 2014 · The Open Neuroscience Journal
  48. The role of bHLH transcription factor NEX in neuronal differentiation and experience-dependent plasticity
    Mikhailova, Olga · 2008
  49. Inhibiting circRNA Cdr1as expression in the ILPFC of adult male C57BL/6J mice impairs fear extinction memory
    Esmi Lau Zajaczkowski, Qiongyi Zhao, Wei‐Siang Liau, Hao Gong, Sachithrani U. Madugalle, Ambika Periyakaruppiah, Laura Jane Leighton, Mason R. B. Musgrove, Haobin Ren, Joshua Davies et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  50. Cellular mechanisms of synaptic plasticity in hippocampal area CA1
    Eric S. Guire · 2006
  51. Insulin Receptor and the Pathophysiology of Alzheimer Disease
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  52. Methods for treating neurological conditions (WO2011159945)
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  53. THE NITRIC OXIDE SYNTHASE ADAPTOR PROTEIN (NOS1AP) ASSOCIATES WITH SCRIBBLE AND REGULATES DENDRITIC SPINE DEVELOPMENT
    L. Richier · 2010 · Library and Archives Canada (Government of Canada)
  54. The neural cell adhesion molecule associates with and signals through p21-activated kinase 1 to regulate neuronal growth cone morphology in mice (Mus musculus Linnaeus, 1758)
    Shen Li · 2009
  55. RegulationofSynapticRac1Activity,Long-Term PotentiationMaintenance,andLearningandMemoryby BCRandABRRacGTPase-ActivatingProteins
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  56. Synapse- and cell-specific plasticity in the mature hippocampus
    Bridget N. Queenan · 2014 · DigitalGeorgetown (Georgetown University Library)
  57. Small GTP-binding Proteins: A Future for the Treatment of Cognitive Disorders?
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  58. Functions of Drosophila Pak (p21-activated kinase) in Morphogenesis: A Mechanistic Model based on Cellular, Molecular, and Genetic Studies
    Sara A. Lewis · 2015 · UA Campus Repository (The University of Arizona)
  59. Introduction: Pushing the Boundary Toward Clinical Application: After 35 Years, PAK Research Comes of Age
    Hiroshi Maruta · 2013 · Elsevier eBooks
  60. METAPLASTICITY IN A MOUSE MODEL OF ALZHEIMER’S DISEASE AND POSSIBLE THERAPEUTIC INTERVENTIONS
    Andrea Megill · 2014
  61. The Role of PAK Signaling in Synaptic Transmission and Plasticity and Social Memory in Mice
    Celeste Leung · 2019 · TSpace (University of Toronto)
  62. Towards a Molecular and Cellular Understanding of Remote Memory
    Brian Joseph Wiltgen, Robert A. M. Brown, Lynn E. Talton, Alcino J. Silva · 2007 · Research and perspectives in neurosciences
  63. Faculty Opinions recommendation of Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.
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  66. Systemic pharmacological suppression of neural activity reverses learning impairment in a mouse model of Fragile X syndrome
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  67. Translational Pain Research: Dendritic Spines as Therapeutic Targets
    Curtis A. Benson, Stephen G. Waxman, Andrew M. Tan · 2025 · Springer eBooks
  68. Second occurrence of the PAK3-R67C variation and multiscale analysis of the corresponding knock-in mice reveal novel phenotypic features and functional synaptic defects
    Manon Dobrigna, Sandrine Poëa‐Guyon, Mathieu Legras, Delphine Le Verger, Kévin Duarte, Catherine Sebrié, Roseline Poirier, Sylvie Granon, Serge Marty, Annick Toutain et al. · 2025 · Neurobiology of Disease
  69. Rôle de Scribble1 dans la formation des synapses glutamatergiques et le trafic des récepteurs NMDA
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  70. The Scrib1 Interactome and its relevance for synaptic plasticity & neurodevelopmental disorders
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  71. Etude de la neurogenèse hippocampique adulte et des fonctions cognitives chez trois souris modèles de déficience intellectuelle
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  72. Du génotype au phénotype : Analyse comparée de mutations du gène de déficience intellectuelle PAK3
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  75. Étude multi-échelle de modèles murins de déficience intellectuelle associée à PAK3
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  77. BindingDB Entry 50022520: Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.
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  78. Scalable Event-Driven Modelling Architectures for Neuromimetic Hardware
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