Nervous Rac: DOCK7 Regulation of Axon Formation
Open accessAbstract
Microtubules play an important role in neuronal polarity. In this issue of Neuron, Watabe-Uchida et al. link a novel Rac-mediated pathway that regulates microtubule dynamics to axon formation.
Integrity signals
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Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
DOCK7 is highly expressed in the brain.
“It is highly expressed in the brain, where it has roles in axon formation, polarity, and myelination (42, 48, 104, 105).”
From RHO to the DOCK for GDP disembarking: Structural insights into the DOCK GTPase nucleotide exchange factors (2021) · cites this paper as [105]
DOCK7 has roles in axon formation, polarity, and myelination.
“It is highly expressed in the brain, where it has roles in axon formation, polarity, and myelination (42, 48, 104, 105).”
From RHO to the DOCK for GDP disembarking: Structural insights into the DOCK GTPase nucleotide exchange factors (2021) · cites this paper as [105]
Cited by
Sorted by citations
Thompson, A. P., Bitsina, C., Gray, J. L., von Delft, F., & Brennan, P. E. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100521 · Cited by 21 · see citing works
“It is highly expressed in the brain, where it has roles in axon formation, polarity, and myelination (42, 48, 104, 105).”
Background
- Authors
- Pinheiro, E. M., & Gertler, F. B.
- Affiliations
- Massachusetts Institute of Technology (US)
- Corresponding author
- Pinheiro, Elaine Maria
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2006-09
- Volume
- 51
- Issue
- 6
- Pages
- 674-676
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2152024956
- Cited by
- 12
- References
- 0
- Citations by year
- 2026: 1 · 2023: 1 · 2021: 2 · 2017: 1 · 2016: 1 · 2015: 1 · 2012: 1
- FWCI
- 0.38
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 2511 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Axon Guidance and Neuronal Signaling
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
- Keywords
- DOCK7, Rac GTPase, axon formation, microtubule dynamics, neuronal polarity, neuronal migration, Rho GTPase signaling
- MeSH terms
- Animals, Axons, Hippocampus, Humans, Models, Biological, Neurons, Phosphorylation, Guanine Nucleotide Exchange Factors, GTPase-Activating Proteins, rac GTP-Binding Proteins, Stathmin
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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