Synaptic Accumulation of PSD-95 and Synaptic Function Regulated by Phosphorylation of Serine-295 of PSD-95

Kim, Myung Jong, Futai, Kensuke, Jo, Jihoon, Hayashi, Yasunori, Cho, Kwangwook, Sheng, Morgan·2007·Neuron
DOI 10.1016/j.neuron.2007.09.007

Cited by (278)

Items 201–278 of 278

  1. Differential Roles of GluN2B in Two Types of Chemical-induced Long Term Potentiation-mediated Phosphorylation Regulation of GluA1 at Serine 845 in Hippocampal Slices
    Bin Zhang, Weiqing Fang, Wu Ma, Fusheng Xue, Heng Ai, Wen Lu · 2020 · Neuroscience
  2. PSD-95 Protein: A Promising Therapeutic Target in Chronic Pain
    Lulin Ma, Dongdong Sun, Song Wen, Jie Yuan, Jing Li, Xinran Tan, Song Cao · 2024 · Molecular Neurobiology
  3. Lipopolysaccharides from Porphyromonas gingivalis indirectly induce neuronal GSK3β-dependent synaptic defects and cause cognitive decline in a low-amyloid-β-concentration environment in Alzheimer's disease
    Shuge Gui, Fan Zeng, Zhou Wu, Saori Nonaka, Tomomi Sano, Junjun Ni, Hiroshi Nakanishi, Masafumi Moriyama, Takashi Kanematsu · 2025 · Journal of Alzheimer s Disease
  4. Poria cocos Regulates Cell Migration and Actin Filament Aggregation in B35 and C6 Cells by Modulating the RhoA, CDC42, and Rho Signaling Pathways
    Chia-Yu Lee, Chang-Ti Lee, I‐Shiang Tzeng, Chan‐Yen Kuo, Fu‐Ming Tsai, Mao‐Liang Chen · 2021 · Evidence-based Complementary and Alternative Medicine
  5. JNK signaling provides a novel therapeutic target for Rett syndrome
    Clara Alice Musi, Anna Castaldo, Anna Elisa Valsecchi, Sara Cimini, Noemi Morello, Riccardo Pizzo, Alessandra Renieri, Ilaria Meloni, Maurizio Rippa Bonati, Maurizio Giustetto et al. · 2021 · BMC Biology
  6. Publishers note
    Kexuan Zhang, Panlin Liao, Jin Wen, Zhonghua Hu · 2022 · IBRO Neuroscience Reports
  7. Stronger learning recruits additional cell-signaling cascades: c-Jun-N-terminal kinase 1 (JNK1) is necessary for expression of stronger contextual fear conditioning
    Prescott T. Leach, Justin W. Kenney, Thomas J. Gould · 2014 · Neurobiology of Learning and Memory
  8. Colocalization and Interaction Study of Neuronal JNK3, JIP1, and β-Arrestin2 Together with PSD95
    Clara Alice Musi, Giacomo Marchini, Arianna Giani, Giovanni Tomaselli, Erica Cecilia Priori, Luca Colnaghi, Tiziana Borsello · 2022 · International Journal of Molecular Sciences
  9. c-Jun-N-terminal kinase 1 is necessary for nicotine-induced enhancement of contextual fear conditioning
    Prescott T. Leach, Justin W. Kenney, Thomas J. Gould · 2016 · Neuroscience Letters
  10. Glycoproteins of Capsosiphon fulvescens modulate synaptic clustering of PSD95 and prevent social isolation-induced cognitive decline in aged male rats
    Jeong Hwan Oh, Youn‐Hee Choi, Taek‐Jeong Nam · 2022 · The Journal of Nutritional Biochemistry
  11. Molecular Mechanisms in Synaptic Plasticity
    Madhavan Mayadevi, G.M. Archana, R. Ramya, R.V. Omkumar · 2012 · InTech eBooks
  12. Emerging roles of Lys63-linked polyubiquitination in neuronal excitatory postsynapses
    Shinhyun Kim, Yinhua Zhang, Chunmei Jin, Yeunkum Lee, Yoonhee Kim, Kihoon Han · 2018 · Archives of Pharmacal Research
  13. Neurobehavioral characterization of Endonuclease G knockout mice reveals a new putative molecular player in the regulation of anxiety
    Albert Giralt, Daniel Sanchı́s, Marta Cherubini, Sílvia Ginés, Xavier Cañas, Joan X. Comella, Jordi Alberch · 2013 · Experimental Neurology
  14. Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
    Ni‐Hsuan Lin, Angela Goh, Shyh‐Horng Lin, Kai‐An Chuang, Chih-Hsuan Chang, Ming‐Han Li, Chu-Hsun Lu, Wen‐Yin Chen, Pei-Hsuan Wei, I-Hong Pan et al. · 2023 · Journal of Alzheimer s Disease Reports
  15. Integrated multi-omic characterizations of the synapse reveal RNA processing factors and ubiquitin ligases associated with neurodevelopmental disorders
    Mei Yuan, Maya L. Gosztyla, Xinzhu Tan, Lara E. Dozier, Brent Wilkinson, Justin McKetney, John J. Y. Lee, Michael Chen, D. S. Tsai, Hema Kopalle et al. · 2025 · Cell Systems
  16. CXCL12 Engages Cortical Inhibitory Neurons to Enhance Dendritic Spine Plasticity and Structured Network Activity
    Chunta Ho, Jared Luchetta, Bradley Nash, Lindsay K. Festa, James A. Johnson, Ahmet Saçan, Joshua G. Jackson, Antonio Sanz-Clemente, Renato Brandimarti, Olimpia Meucci · 2025 · Journal of Neuroscience
  17. Vasopressin acts as a synapse organizer in limbic regions by boosting PSD95 and GluA1 expression
    Limei Zhang, Teresa Padilla‐Flores, Vito S. Hernández, Mario A. Zetter, Elba Campos‐Lira, Laura I. Escobar, Robert Peter Millar, Lee E. Eiden · 2022 · Journal of Neuroendocrinology
  18. Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR
    Fengmei Wei, Xiao Yan Deng, Bo Ma, Wenhao Li, Yajie Chen, Long Zhao, Yi‐Shu Zhang, Tingjuan Zheng, Donghua Xian, Yunqing He et al. · 2022 · Cellular and Molecular Neurobiology
  19. On the effect of hippocampal c-Jun N-terminal kinase inhibition on object recognition memory
    Janine I. Rossato, Andressa Radiske, María Carolina González, Lia R. Bevilaqua, Martı́n Cammarota · 2022 · Frontiers in Behavioral Neuroscience
  20. Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites
    Marius F. Ifrim, Aleksandra Janusz, Gary Jonathan Bassell · 2022 · Cell Reports
  21. The JNK signaling pathway as a potential new target for depression
    Juntao Zhang, Wenjuan Lin · 2018 · Chinese Science Bulletin (Chinese Version)
  22. Biochemical and morphological characterization of SEPT1 in mouse brain
    Hidenori Ito, Rika Morishita, Mariko Noda, Ikuko Iwamoto, Koh‐ichi Nagata · 2020 · Medical Molecular Morphology
  23. Radiolabeled Aminopyrazoles as Novel Isoform Selective Probes for pJNK3 Quantification
    Brian C. Bales, Victoria E. Cotero, Dan E. Meyer, Jeannette C. Roberts, Monica Rodríguez-Silva, Tiberiu M. Siclovan, Jeremy W. Chambers, Michael J. Rishel · 2022 · ACS Medicinal Chemistry Letters
  24. From synapses to circuits and back: Bridging levels of understanding in animal models of Alzheimer's disease
    Udaysankar Chockanathan, Krishnan Padmanabhan · 2022 · European Journal of Neuroscience
  25. Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
    Sung-Soo Jang, Han Gil Jeong, Hee Jung Chung · 2017 · Journal of Visualized Experiments
  26. Effects of early life overnutrition and hyperandrogenism on spatial learning and memory in a rat model of polycystic ovary syndrome.
    Đurđica Ignjatović, Gordana Tovilović-Kovačević, B. Mićić, M. Tomić, A. Djordjevic, D. Macut, D. Vojnović Milutinović · 2023 · Hormones and Behavior
  27. Synaptic scaffold protein PSD-95: a therapeutic target for Alzheimer’s disease
    Xing Fan, Hao Wang, Jianchao Ping, Mingzhe Li, Jianlan Gu, Wei Qian · 2025 · Biochemical Pharmacology
  28. Neuronal Stress and Its Hormetic Aspects
    Sarah Ann Hofbrucker-MacKenzie, Iswariya Sivaprakasam, Yuanyuan Ji, Michael Manfred Kessels, Britta Qualmann · 2018 · Elsevier eBooks
  29. Role of Autophagy in Brain Sculpture: Physiological and Pathological Implications
    Annalisa Nobili, Virve Cavallucci, Marcello D’Amelio · 2016 · Springer eBooks
  30. Prolonged intermittent theta burst stimulation enhances hippocampal plasticity via GluN2A-mediated signaling
    Danica Popović, Marina Zarić Kontić, Milica Zeljković, Milena M. Milosevic, Teodora Martić, Tamara Radukic, Andjela Stekić, Emilija Glavonic, Ana Jakovljević, Katarina Mihajlović et al. · 2026 · Frontiers in Aging Neuroscience
  31. Molecular crosstalk between MAPK signaling and neuroprotective pathways in Parkinson's disease: from pathogenesis to therapeutic potential.
    M. Shalabi, Hayder M. Al-kuraishy, Mustafa M. Shokr, G. Batiha · 2026 · Neuroscience
  32. JNK activity modulates postsynaptic scaffold protein SAP102 and kainate receptor dynamics in dendritic spines
    Stella‐Amrei Kunde, Bettina Schmerl, Judith von Sivers, Elham Ahmadyar, Taanisha Gupta, Nils Rademacher, Hanna L. Zieger, Sarah A. Shoichet · 2024 · Journal of Biological Chemistry
  33. The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia
    Jiaxin Cheng, Chunhui Wu, Yu Wang, Zhen Wang, He Yang, Jingshan Shen · 2024 · Pharmacology Biochemistry and Behavior
  34. Crosstalk between biochemical signaling and trafficking determines AMPAR dynamics in synaptic plasticity
    Miriam K. Bell, Padmini Rangamani · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  35. Epigenetic changes, neuronal dysregulation and metabolomic abnormalities in Zmym2 mutant mice, a genetic model of schizophrenia and neurodevelopmental disorders
    Wei-Chao Huang, Kira A. Perzel Mandell, Sameer Aryal, Bryan J. Song, Antia Valle-Tojeiro, Nathaniel Goble, Chuhan Geng, Ahmet S. Asan, Xiao‐Man Liu, Courtney Dennis et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  36. Role of the different domains of PSD-95 in basal synaptic transmission
    A.D. Stéphanie Bonnet · 2011
  37. Convergence and divergence of molecular mechanisms in Hebbian and homeostatic plasticity
    Kira M. Feighan, Harshit K. Thakare, Stephen D. Glasgow, Timothy E. Kennedy · 2026 · Frontiers in Synaptic Neuroscience
  38. RBFOX1 Dysfunction Unlocks APOE4 ‐Associated Microglial Genesis and Exacerbates Alzheimer's Pathology in Human Cerebral Organoids
    Bowen Zhang, Changjie Shi, Jiayi Zhao, Qiuhong Hua, Houchun Zhang, Hailin Gao, Yuanyuan Qian, Jiaxue Cha, Jing Li, Jiayao Chen et al. · 2026 · Exploration
  39. Calcium signaling and postsynaptic density dynamics: the roles of calmodulin in synaptic protein regulation
    Keyaa Shah, Yonghong Zhang · 2026 · Frontiers in Molecular Neuroscience
  40. Hyperfunction of PSD-95 leads to hyperexcitability and cognitive abnormalities in MEF2C haploinsufficiency
    Meijin Pan, Anirudh R. Acharya, Kwan Young Lee, Justin S. Rhodes, Nien‐Pei Tsai · 2026 · Proceedings of the National Academy of Sciences
  41. Wnt signaling
    Patricia C. Salinas · 2020 · Elsevier eBooks
  42. Pathobiological Mechanisms and Treatment of Electrophysiological Dysfunction Following Primary Blast-Induced Traumatic Brain Injury
    Vogel III, Edward Weigand · 2017
  43. Wnt Signaling
    Patricia C. Salinas · 2013 · Elsevier eBooks
  44. Palmitoylation Couples DLK to JNK3 to Facilitate Pro-degenerative Axon-to-Soma Signaling
    Jingwen Niu, Sabrina M. Holland, Andrea Ketschek, Kaitlin M. Collura, Takashi Hayashi, Gianluca Gallo, Gareth M. Thomas · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  45. Antidepressant Interactions of Ketamine and Glycogen Synthase Kinase-3 (GSK3) in Mice
    Kimberlee Downey · 2015
  46. Correlated plasticity of synaptic structures and its relationship to the stabilization of synaptic enlargement
    Daniel Meyer · 2013 · MPG.PuRe (Max Planck Society)
  47. Biomarker Analysis with Grating Coupled Surface Plasmon Coupled Fluorescence
    Alvaro Mendoza, James A. Dias, Theodore Zeltner, David A. Lawrence · 2014 · Journal of Advances in Biology & Biotechnology
  48. HNRNP K: A NEW PROTEIN IN NEURON DEVELOPMENT AND FUNCTION
    Alessandra Folci · 2012 · Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)
  49. Molecular Assembly of Excitatory Synapses
    Hirohide Iwasaki, Shinji Tanaka, Shigeo Okabe · 2016 · Springer eBooks
  50. Efeitos da exposição à fumaça do cigarro com diferentes concentrações de nicotina nos elementos da transmissão sináptica no início do período pós-natal de camundongos
    Stephanie de Oliveira Duro · 2017
  51. Disease-associated scaffold protein CNK2 modulates PSD size and influences trafficking of new synaptic binding partner TNIK
    Hanna L. Zieger, Stella‐Amrei Kunde, Nils Rademacher, Bettina Schmerl, Sarah A. Shoichet · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  52. Structure and dynamics of the MAGUK core of PSD-95
    Jun Zhang · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  53. Notas dispersas sobre don Isidoro Queimaliños Queimaliños
    Amado Ricón Virulegio · 2009 · Dialnet (Universidad de la Rioja)
  54. Experiences Shape Hippocampal Neuron Morphology and the Balance of CRHR1 and OTR
    Fengmei Wei, Xiao Yan Deng, Bo Ma, Wenhao Li, Yajie Chen, Long Zhao, Yishu Zhang, Tingjuan Zheng, Donghua Xian, Yunqing He et al. · 2022 · Research Square
  55. Quantitative Nanoscopy of Synaptic Sites
    Clara‐Marie Gürth · 2023
  56. Simple Method for the Preparation of Postsynaptic Density Fraction from Mouse Brain
    Hidenori Ito, Rika Morishita, Koh‐ichi Nagata · 2024 · Methods in molecular biology
  57. Revealing Acute Consequences of Rapid Protein Elimination at Individual Synapses using Auxin-Inducible Degron 2 Technology
    Lilach Elbaum, Weixiang Yuan, Johannes P.-H. Seiler, Nadia Blom, Ya-Chien Chan, Ali Hyder Baig, Nils Brose, Simon Rumpel, Noam E. Ziv · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  58. Ca2+-PP2B-PSD-95 axis: A novel regulatory mechanism of the phosphorylation state of Serine 295 of PSD-95
    Takahiko Chimura, Toshiya Manabe · 2024 · PLoS ONE
  59. Transcriptional and synaptic regulation of NMDA glutamate receptor-mediated hippocampal plasticity and memory
    Arnaldo Parra‐Damas, Anna del Ser‐Badia, Xavier Fernandez-Olalla, Ángel Deprada-Fernandez, Lilian Enríquez-Barreto, José Prius-Mengual, Judit Català-Solsona, Verónica Brito, José Rodrı́guez-Álvarez, Sílvia Ginés et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  60. Playback of ultrasonic vocalisations (38–48 kHz) communicates the state of stress and impaired context episodic memory in adolescent rats
    Selvavinayagam Dhivakar, Koilmani Emmanuvel Rajan · 2025 · Neuroscience Letters
  61. Exploration of schizophrenia-related behavioral and molecular abnormalities in a mutant mouse model with a mutation in the TVV motif of the ErbB4 gene
    Abdul Aziz Khan, Shuai Wang, Ziying Wang, Zainab Rehman, Leilei Chen, Yifang Kuang, Xu Zhang, Yuting Li, Jiarun Yang, Jun Ye et al. · 2025 · Molecular Brain
  62. Gut Microbiota-Mediated Modulation of Neurodevelopmental Behavior in CLCN4- Deficient Mice
    Yura Choi, Shambhunath Bose, Jihong Oh, Eun‐Ji Song, Young‐Do Nam, Songhee Jeon, Hojun Kim · 2025 · Research Square
  63. Site-Specific Regulation of Tau phosphorylation by MAPK pathways during HFS-Induced synaptic plasticity in the Rat hippocampus
    Cem Süer, Burak Tan, Nurcan Dursun, Bilal Koşar, Ercan Babür · 2025 · Neuroscience Letters
  64. Revealing acute consequences of rapid degradation of synaptic fusion proteins at individual synapses using Auxin-Inducible Degron 2 technology
    Lilach Elbaum, Weixiang Yuan, Johannes P.-H. Seiler, Nadia Blom, Ya-Chien Chan, Ali Hyder Baig, Nils Brose, Simon Rumpel, Noam E. Ziv · 2025 · Communications Biology
  65. Etude de la dynamique de tau dans le compartiment synaptique dans un contexte physiologique et pathologique exemple de la maladie d'Alzheimer
    Marie‐Lise Frandemiche · 2013 · theses.fr (ABES)
  66. Organisation et dynamique des protéines d'échafaudage de la postsynapse glutamatergique : implications dans la physio-pathologie de la transmission synaptique.
    Enora Moutin · 2011 · theses.fr (ABES)
  67. The role of complement system related genes in synapse formation and specificity in the olivo-cerebellar network
    Keerthana Iyer · 2015 · theses.fr (ABES)
  68. Investigating the molecular pathways driving the sumoylation/desumoylation balance in rat hippocampal synapses
    Lenka Schorova · 2018 · theses.fr (ABES)
  69. Super-resolution imaging reveals differential organization and regulation of NMDA receptor subtypes
    Blanka Kellermayer · 2018 · theses.fr (ABES)
  70. Structural and functional plasticity of the olfactory bulb inhibitory interneurons during diverse sensory experiences
    Soham Saha · 2019 · theses.fr (ABES)
  71. Interaction between synaptic and structural plasticity
    Côme Camus · 2021 · theses.fr (ABES)
  72. From biogenesis to synaptic organization : developing tools to study AMPAR-associated proteins
    Diogo Bessa‐Neto · 2021 · theses.fr (ABES)
  73. The Molecular Machinery of Synaptic Plasticity and Its Potential Role in the Aetiology of Schizophrenia
    BRIAN J. MORRIS · 2026 · Molecular Neurobiology
  74. Adolescent dietary restriction improves cognition and frailty in aged female Wistar rats
    Valentina Simeunovic, Aleksandra Mladenović, Milica Prvulović, Milena Jovic, Smilja Praćer, Srdjan J. Sokanovic · 2026 · The Journals of Gerontology Series A
  75. Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory
    Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qianqian Ding, Si-Ying Wang, Ting Cao, Xuan‐Ying Chen, Wucheng Tao, Lin Shen et al. · 2026 · Advanced Science
  76. Neuroligins and Neuropathic Pain: Insights into Synaptic Plasticity and Pain Transmission
    Mario García‐Domínguez · 2026 · Biology
  77. Inhibition of miR-206 Ameliorates Seizures and Cognitive Deficits via BDNF/TrkB Signaling in Pilocarpine-Induced TLE Mice
    Hua Zhang, Zheng-Xu Cai · 2026 · Brain Sciences
  78. Targeting the gut–brain axis with Bifidobacterium breve in neurodegeneration: A comprehensive narrative review of current evidence in Alzheimer's disease and cognitive aging
    Olia Hamzeh, Mehrdad Halaji, Ali Rostami, Ghulam Md Ashraf · 2026 · Journal of Alzheimer s Disease