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Cited by 382

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Polymorphisms in the Drug Transporter Gene ABCB1 Predict Antidepressant Treatment Response in Depression

Open access
Uhr, Manfred, Tontsch, Alina, Namendorf, Christian, Ripke, Stephan, Lucae, Susanne, Ising, Marcus, Dose, Tatjana, Ebinger, Martin, Rosenhagen, Marcus, Kohli, Martin, Kloiber, Stefan, Salyakina, Daria, Bettecken, Thomas, Specht, Michael, Pütz, Benno, Binder, Elisabeth B., Müller-Myhsok, Bertram, Holsboer, Florian·2008·Neuron
DOI 10.1016/j.neuron.2007.11.017
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Research works printed but not linked: 25

  1. Ambudkar, 1999, Biochemical, cellular, and pharmacological aspects of the multidrug transporter, Annu. Rev. Pharmacol. Toxicol., 39, 361, 10.1146/annurev.pharmtox.39.1.361 · DOI · Paper page
  2. Callen, 1987, Localization of the human multiple drug resistance gene, MDR1, to 7q21.1, Hum. Genet., 77, 142, 10.1007/BF00272381 · DOI
  3. Cascorbi, 2006, Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs, Pharmacol. Ther., 112, 457, 10.1016/j.pharmthera.2006.04.009 · DOI · Paper page
  4. Cascorbi, 2001, Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects, Clin. Pharmacol. Ther., 69, 169, 10.1067/mcp.2001.114164 · DOI · Paper page
  5. Cordon-Cardo, 1989, Multidrug resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites, Proc. Natl. Acad. Sci. USA, 86, 695, 10.1073/pnas.86.2.695 · DOI · Paper page
  6. Devault, 1990, Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities, Mol. Cell. Biol., 10, 1652
  7. Grauer, 2004, P-glycoprotein reduces the ability of amitriptyline to cross the blood brain barrier in mice after a 10-day administration of amitriptyline, J. Psychopharmacol., 18, 66, 10.1177/0269881104042831 · DOI
  8. Hoffmeyer, 2000, Functional polymorphisms of the human multidrug resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo, Proc. Natl. Acad. Sci. USA, 97, 3473, 10.1073/pnas.97.7.3473 · DOI · Paper page
  9. Ito, 2001, Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects, Pharmacogenetics, 11, 175, 10.1097/00008571-200103000-00008 · DOI
  10. Kim, 2002, MDR1 single nucleotide polymorphisms: multiplicity of haplotypes and functional consequences, Pharmacogenetics, 12, 425, 10.1097/00008571-200208000-00002 · doi:10.1097/00008571-200208000-00002
  11. Kim, 2001, Identification of functionally variant MDR1 alleles among European Americans and African Americans, Clin. Pharmacol. Ther., 70, 189, 10.1067/mcp.2001.117412 · DOI · Paper page
  12. Kroetz, 2003, Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene, Pharmacogenetics, 13, 481, 10.1097/00008571-200308000-00006 · DOI · Paper page
  13. McMahon, 2006, Variation in the gene encoding the serotonin 2a receptor is associated with outcome of antidepressant treatment, Am. J. Hum. Genet., 78, 804, 10.1086/503820 · DOI · Paper page
  14. Murray, 1996, Evidence-based health policy - lessons from the Global Burden of Disease Study, Science, 274, 740, 10.1126/science.274.5288.740 · DOI · Paper page
  15. Sakaeda, 2003, Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs, Pharmacogenomics, 4, 397, 10.1517/phgs.4.4.397.22747 · doi:10.1517/phgs.4.4.397.22747
  16. Schinkel, 1996, P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs, J. Clin. Invest., 97, 2517, 10.1172/JCI118699 · DOI · Paper page
  17. Tanabe, 2001, Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene, J. Pharmacol. Exp. Ther., 297, 1137, 10.1016/S0022-3565(24)29643-9 · DOI · Paper page
  18. Tang, 2004, Genomic evidence for recent positive selection at the human MDR1 gene locus, Hum. Mol. Genet., 13, 783, 10.1093/hmg/ddh099 · DOI
  19. Thiebaut, 1987, Cellular localization of the multidrug resistance gene product P-glycoprotein in normal human tissues, Proc. Natl. Acad. Sci. USA, 84, 7735, 10.1073/pnas.84.21.7735 · DOI · Paper page
  20. Uhr, 2003, abcb1ab P-glycoprotein is involved in the uptake of citalopram and trimipramine into the brain of mice, J. Psychiatr. Res., 37, 179, 10.1016/S0022-3956(03)00022-0 · DOI
  21. Uhr, 2000, Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption, Neuropsychopharmacology, 22, 380, 10.1016/S0893-133X(99)00095-0 · DOI
  22. Uhr, 2002, Penetration of endogenous steroid hormones corticosterone, cortisol, aldosterone and progesterone into the brain is enhanced in mice deficient for both mdr1a and mdr1b P-glycoproteins, J. Neuroendocrinol., 14, 753, 10.1046/j.1365-2826.2002.00836.x · DOI
  23. Uhr, 2003, Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-glycoprotein gene disruption, Biol. Psychiatry, 54, 840, 10.1016/S0006-3223(03)00074-X · DOI
  24. Uhr, 2007, Blood-brain barrier penetration and pharmacokinetics of amitriptyline and its metabolites in P-glycoprotein (abcb1ab) knock-out mice and controls, J. Psychiatr. Res., 41, 179, 10.1016/j.jpsychires.2005.10.005 · DOI
  25. Wigginton, 2005, A note on exact tests of Hardy-Weinberg equilibrium, Am. J. Hum. Genet., 76, 887, 10.1086/429864 · DOI · Paper page

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Metadata

Authors
Uhr, M., Tontsch, A., Namendorf, C., Ripke, S., Lucae, S., Ising, M., Dose, T., Ebinger, M., Rosenhagen, M., Kohli, M., Kloiber, S., Salyakina, D., Bettecken, T., Specht, M., Pütz, B., Binder, E. B., Müller-Myhsok, B., & Holsboer, F.
Venue
Neuron
Publisher
Elsevier BV
Published
2008-01
Volume
57
Issue
2
Pages
203-209
ISSN
0896-6273 (ISSN-L)
DOI
10.1016/j.neuron.2007.11.017
OpenAlex
W2061800286
Cited by
382
References
6
FWCI
32.27
Type
journal article
Language
en
Open access
bronze
Licence

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CoChat. (2026). Citation check: Polymorphisms in the Drug Transporter Gene ABCB1 Predict Antidepressant Treatment Response in Depression. https://app.cochat.ai/papers/10.1016/j.neuron.2007.11.017
The paper
Uhr, M., Tontsch, A., Namendorf, C., Ripke, S., Lucae, S., Ising, M., Dose, T., Ebinger, M., Rosenhagen, M., Kohli, M., Kloiber, S., Salyakina, D., Bettecken, T., Specht, M., Pütz, B., Binder, E. B., Müller-Myhsok, B., & Holsboer, F. (2008). Polymorphisms in the Drug Transporter Gene ABCB1 Predict Antidepressant Treatment Response in Depression. Neuron. https://doi.org/10.1016/j.neuron.2007.11.017

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.