The Function of α-Synuclein

Cites (318)

Items 201–318 of 318

  1. Oxidative post‐translational modifications of α‐synuclein in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) mouse model of Parkinson's disease
    Serge Przedborski, Qiping Chen, Miquel Vila, Benoit I. Giasson, Ruth Djaldatti, Slobodanka Vukosavić, José M. Souza, Vernice R. Jackson-Lewis, Virginia M.‐Y. Lee, Harry Ischiropoulos · 2001 · Journal of Neurochemistry
  2. Mitochondrial translocation of α-synuclein is promoted by intracellular acidification
    Nelson B. Cole, Diane DiEuliis, Paul Leo, Drake C. Mitchell, Robert Luke Nussbaum · 2008 · Experimental Cell Research
  3. Altered Fatty Acid Composition of Dopaminergic Neurons Expressing α-Synuclein and Human Brains with α-Synucleinopathies
    Ronit Sharon, Ifat Bar-Joseph, Gudrun E. Mirick, Charles Nicholas Serhan, Dennis J. Selkoe · 2003 · Journal of Biological Chemistry
  4. Familial Mutants of α-Synuclein with Increased Neurotoxicity Have a Destabilized Conformation
    Carlos W. Bertoncini, Claudio O. Fernández, Christian Griesinger, Thomas M. Jovin, Markus Zweckstetter · 2005 · Journal of Biological Chemistry
  5. Stabilization of α-Synuclein Protein with Aging and Familial Parkinson's Disease-Linked A53T Mutation
    Wenxue Li, Christian Lesuisse, Yanqun Xu, Juan Carlos Troncoso, Donald L. Price, Michael K. Lee · 2004 · Journal of Neuroscience
  6. Macromolecular Crowding in the Escherichia coli Periplasm Maintains α-Synuclein Disorder
    Brian C. McNulty, Gregory B. Young, Gary J. Pielak · 2005 · Journal of Molecular Biology
  7. Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage
    Christine C. Stichel, Xin‐Ran Zhu, Verian Bader, Bettina Linnartz‐Gerlach, S. Schmidt, Hermann Lübbert · 2007 · Human Molecular Genetics
  8. Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: A biological link between Gaucher disease and parkinsonism
    Amy Manning-Bog, Birgitt Schüle, J. William Langston · 2009 · NeuroToxicology
  9. Motor dysfunction and gliosis with preserved dopaminergic markers in human α-synuclein A30P transgenic mice
    Teresa Gómez‐Isla, Michael C. Irizarry, Ami Mariash, Bonnie S. Cheung, Oscar Soto, Stefanie E. Schrump, Jesse Sondel, Linda Kotilinek, John Day, Michael A. Schwarzschild et al. · 2002 · Neurobiology of Aging
  10. Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies
    Michel Goedert · 1999 · Philosophical Transactions of the Royal Society B Biological Sciences
  11. α-Synuclein fate is determined by USP9X-regulated monoubiquitination
    Ruth Rott, Raymonde Szargel, Joseph Haskin, Rina Bandopadhyay, Andrew John Lees, Vered Shani, Simone Engelender · 2011 · Proceedings of the National Academy of Sciences
  12. A role for phospholipase D1 in neurotransmitter release
    Yann Humeau, Nicolas Vitale, Sylvette Chasserot‐Golaz · 2001 · Proceedings of the National Academy of Sciences
  13. β-Synuclein gene alterations in dementia with Lewy bodies
    H. Ohtake, Pornprot Limprasert, Yuxin Fan, Osamu Onodera, Akiyoshi Kakita, Hitoshi Takahashi, Lauren T. Bonner, Debby W. Tsuang, Ian V.J. Murray, Virginia M.-Y. Lee et al. · 2004 · Neurology
  14. α‐Synuclein and Polyunsaturated Fatty Acids Promote Clathrin‐Mediated Endocytosis and Synaptic Vesicle Recycling
    Ben Gedalya, Tziona, Loeb, Virginie, Israeli, Eitan, Altschuler, Yoram, Selkoe, Dennis J., Sharon, Ronit · 2009 · Traffic
  15. Regulated Exocytosis in Chromaffin Cells
    Anne‐Sophie Caumont, Marie‐Christine Galas, Nicolas Vitale · 1998 · Journal of Biological Chemistry
  16. Involvement of macroautophagy in the dissolution of neuronal inclusions
    Hardy J. Rideout, Isabelle Lang‐Rollin, Leonidas Stefanis · 2004 · The International Journal of Biochemistry & Cell Biology
  17. Altered expression of the synuclein family mRNA in Lewy body and Alzheimer’s disease
    Edward M. Rockenstein, Lawrence A. Hansen, Margaret E. Mallory, John Q. Trojanowski, Douglas R Galasko, Eliezer Masliah · 2001 · Brain Research
  18. Dynamics of α‐synuclein aggregation and inhibition of pore‐like oligomer development by β‐synuclein
    Igor F. Tsigelny, Pazit Bar‐On, Yuriy Sharikov, Leslie A. Crews, Makoto Hashimoto, Mark A. Miller, Steve H. Keller, Oleksandr Platoshyn, Jason X.‐J. Yuan, Eliezer Masliah · 2007 · FEBS Journal
  19. Impairment of microtubule‐dependent trafficking by overexpression of α‐synuclein
    He-Jin Lee, Farnaz Khoshaghideh, Stephen B. Lee, Seung‐Jae Lee · 2006 · European Journal of Neuroscience
  20. Progression and staging of Lewy pathology in brains from patients with dementia with Lewy bodies
    Wami Marui, Eizo Iseki, Toshiki Nakai, Satoshi Miura, Masanori Kato, Kenji Uéda, Kenji Kosaka · 2002 · Journal of the Neurological Sciences
  21. Increased striatal dopamine release and hyperdopaminergic‐like behaviour in mice lacking both alpha‐synuclein and gamma‐synuclein
    Steven L. Senior, Natalia N. Ninkina, Robert M. J. Deacon, David M. Bannerman, Vladimir L. Buchman, Stephanie Jane Cragg, Richard Wade‐Martins · 2008 · European Journal of Neuroscience
  22. Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein in mice
    Masaki Wakamatsu, Aiko Ishii, Shingo Iwata, Junko Sakagami, Yuriko Ukai, Mieko Ono, Daiji Kambe, Shin‐ichi Muramatsu, Kazuto Kobayashi, Takeshi Iwatsubo et al. · 2006 · Neurobiology of Aging
  23. α-Synuclein–induced Aggregation of Cytoplasmic Vesicles inSaccharomyces cerevisiae
    James H. Soper, Subhojit Roy, Anna Stieber, Eliza Lee, Robert B. Wilson, John Q. Trojanowski, Christopher G. Burd, Virginia M.‐Y. Lee · 2008 · Molecular Biology of the Cell
  24. Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of γ‐synuclein, α‐synuclein and double α/γ‐synuclein null mutant mice
    Darren C. Robertson, Oliver Schmidt, Natalia N. Ninkina, Paul A. Jones, John Sharkey, Vladimir L. Buchman · 2004 · Journal of Neurochemistry
  25. RESEARCH ARTICLE: Empiric Refinement of the Pathologic Assessment of Lewy‐Related Pathology in the Dementia Patient
    James B. Leverenz, Ronald L. Hamilton, Debby W. Tsuang, Aimee M. Schantz, Darcy A. Vavrek, Eric Berg Larson, Walter A. Kukull, Oscar L. López, Douglas R Galasko, Eliezer Masliah et al. · 2008 · Brain Pathology
  26. Papp–Lantos inclusions and the pathogenesis of multiple system atrophy: an update
    K. A. Jellinger, Peter L Lantos · 2010 · Acta Neuropathologica
  27. CSPα knockout causes neurodegeneration by impairing SNAP‐25 function
    Manu Sharma, Jacqueline Burré, Peter Bronk, Yingsha Zhang, Wei Xu, Thomas Christian Südhof · 2011 · The EMBO Journal
  28. Structured Regions of α-Synuclein Fibrils Include the Early-Onset Parkinson's Disease Mutation Sites
    Gemma Comellas, Luisel Lemkau, Andrew J. Nieuwkoop, Kathryn D. Kloepper, Daniel T. Ladror, Reika Ebisu, Wendy S. Woods, Andrew S. Lipton, Julia M. George, Chad M. Rienstra · 2011 · Journal of Molecular Biology
  29. Role of α-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice
    Oliver M. Schlüter, Francesco Fornai, M. Alessandri, Saika TAKAMORI, Martin Geppert, Reinhard Jahn, Thomas Christian Südhof · 2003 · Neuroscience
  30. Helix periodicity, topology, and dynamics of membrane‐associated α‐Synuclein
    Robert Bussell, Trudy F. Ramlall, David Eliezer · 2005 · Protein Science
  31. Intracellular Patch Electrochemistry: Regulation of Cytosolic Catecholamines in Chromaffin Cells
    Eugene V. Mosharov, Liang‐Wei Gong, Bhavanna Khanna, David Sulzer, Manfred Lindau · 2003 · Journal of Neuroscience
  32. Beating a dead horse
    J. Eric Ahlskog · 2007 · Neurology
  33. Membrane Curvature Sensing by Amphipathic Helices
    Martin Borch Jensen, Vikram Kjøller Bhatia, Christine C. Jao, Jakob Ewald Rasmussen, Søren Ljungberg Pedersen, Knud J. Jensen, Ralf Langen, Dimitrios G. Stamou · 2011 · Journal of Biological Chemistry
  34. Structural Intermediates during α-Synuclein Fibrillogenesis on Phospholipid Vesicles
    Gemma Comellas, Luisel Lemkau, Donghua H. Zhou, Julia M. George, Chad M. Rienstra · 2012 · Journal of the American Chemical Society
  35. Increased Expression of Rat Synuclein in the Substantia Nigra Pars Compacta Identified by mRNA Differential Display in a Model of Developmental Target Injury
    Nikolai G. Kholodilov, Michael Neystat, F. Oo Tinmarla, E. Lo Steven, Kristin E. Larsen, David L. Sulzer, Robert E. Burke · 1999 · Journal of Neurochemistry
  36. Proteasomal Inhibition-Induced Inclusion Formation and Death in Cortical Neurons Require Transcription and Ubiquitination
    Hardy J. Rideout, Leonidas Stefanis · 2002 · Molecular and Cellular Neuroscience
  37. Evidence in favor of Braak staging of Parkinson's disease
    Dennis W. Dickson, Hirotake Uchikado, Hiroshige Fujishiro, Yoshio Tsuboi · 2010 · Movement Disorders
  38. γ-Synuclein Promotes Cancer Cell Survival and Inhibits Stress- and Chemotherapy Drug-induced Apoptosis by Modulating MAPK Pathways
    Zhongzong Pan, Wendy Bruening, Benoit I. Giasson, Virginia M.‐Y. Lee, Andrew K. Godwin · 2002 · Journal of Biological Chemistry
  39. Mapping the Subcellular Distribution of α-Synuclein in Neurons using Genetically Encoded Probes for Correlated Light and Electron Microscopy: Implications for Parkinson's Disease Pathogenesis
    Daniela Boassa, Monica L. Berlanga, Mary Ann Yang, Masako Terada, Junru Hu, Eric A. Bushong, Minju Hwang, Eliezer Masliah, Julia M. George, Mark H. Ellisman · 2013 · Journal of Neuroscience
  40. Gene transfer of a reserpine-sensitive mechanism of resistance to N-methyl-4-phenylpyridinium.
    Yanqiu Liu, Ali Roghani, Robert H. Edwards · 1992 · Proceedings of the National Academy of Sciences
  41. A quantitative investigation of neuronal cytoplasmic and intranuclear inclusions in the pontine and inferior olivary nuclei in multiple system atrophy
    Nishie, M., Mori, F., Yoshimoto, M., Takahashi, H., Wakabayashi, K. · 2004 · Neuropathology and Applied Neurobiology
  42. Abnormal colonic motility in mice overexpressing human wild-type α-synuclein
    Lixin Wang, Sheila M. Fleming, Marie‐Françoise Chesselet, Yvette Taché · 2008 · Neuroreport
  43. Synphilin-1 Is Developmentally Localized to Synaptic Terminals, and Its Association with Synaptic Vesicles Is Modulated by α-Synuclein
    Cátia S. Ribeiro, K. Carneiro, Christopher A. Ross, João R.L. Menezes, Simone Engelender · 2002 · Journal of Biological Chemistry
  44. The role of Ser129 phosphorylation of α-synuclein in neurodegeneration of Parkinson’s disease: a review of in vivo models
    Hiroyasu Sato, Takeo Kato, Shigeki Arawaka · 2013 · Reviews in the Neurosciences
  45. Accumulation of phosphorylated a-synuclein in the brain and peripheral ganglia of patients with multiple system atrophy
    Makoto Nishie, Fumiaki Mori, Hideo Fujiwara, Masato Hasegawa, Makoto Yoshimoto, Takeshi Iwatsubo, Hitoshi Takahashi, Koichi Wakabayashi · 2004 · Acta Neuropathologica
  46. Gene expression profile of oxidant stress and neurodegeneration in transgenic mice deficient in α-tocopherol transfer protein
    Kishorchandra Gohil, Bettina C. Schock, Abhishek A. Chakraborty, Yuko Terasawa, Jacob Raber, Robert V. Farese, Lester Packer, Carroll Edward Cross, Maret G. Traber · 2003 · Free Radical Biology and Medicine
  47. Inhibition of α-Synuclein Fibrillization by Dopamine Is Mediated by Interactions with Five C-Terminal Residues and with E83 in the NAC Region
    Fernando E. Herrera, Alessandra Chesi, Katerina E. Paleologou, Adrien W. Schmid, Adriana Munoz, Michele Vendruscolo, Stefano Gustincich, Hilal Ahmed Lashuel, Paolo Carloni · 2008 · PLoS ONE
  48. Mice Lacking α-Synuclein have an Attenuated Loss of Striatal Dopamine Following Prolonged Chronic MPTP Administration
    Robert E. Drolet, Bahareh Behrouz, Keith J. Lookingland, John L. Goudreau · 2004 · NeuroToxicology
  49. α-Synuclein Membrane Association Is Regulated by the Rab3a Recycling Machinery and Presynaptic Activity*
    Robert HC Chen, Sabine Wislet‐Gendebien, Filsy Samuel, Naomi P. Visanji, Gang Zhang, Diana Marsilio, Tammy Langman, Paul E. Fraser, Anurag Tandon · 2013 · Journal of Biological Chemistry
  50. γ-Synucleinopathy: neurodegeneration associated with overexpression of the mouse protein
    Natalia N. Ninkina, Owen M. Peters, Steven J. Millership, Hatem Salem, Herman van der Putten, Vladimir L. Buchman · 2009 · Human Molecular Genetics
  51. Remodeling of Lipid Vesicles into Cylindrical Micelles by α-Synuclein in an Extended α-Helical Conformation
    Naoko Mizuno, Jobin Varkey, Natalie C. Kegulian, Balachandra Gajanan Hegde, Naiqian Cheng, Ralf Langen, Alasdair C. Steven · 2012 · Journal of Biological Chemistry
  52. Co‐expression of C‐terminal truncated alpha‐synuclein enhances full‐length alpha‐synuclein‐induced pathology
    Ayşe Ulusoy, Fabia Febbraro, Poul Henning Jensen, Deniz Kirik, Marina Romero‐Ramos · 2010 · European Journal of Neuroscience
  53. Synuclein deposition and non-motor symptoms in Parkinson disease
    K. A. Jellinger · 2011 · Journal of the Neurological Sciences
  54. α-Synuclein Gene Deletion Decreases Brain Palmitate Uptake and Alters the Palmitate Metabolism in the Absence of α-Synuclein Palmitate Binding
    Mikhail Y. Golovko, Nils Joakim Færgeman, Nelson B. Cole, Paula I. Castagnet, Robert Luke Nussbaum, Eric J. Murphy · 2005 · Biochemistry
  55. First appraisal of brain pathology owing to A30P mutant alpha‐synuclein
    Kay Seidel, Ludger J. Schöls, Silke Nuber, Elisabeth Petrasch‐Parwez, Kristin Gierga, Zbigniew K. Wszołek, Dennis W. Dickson, Wei Gai, Antje Bornemann, Olaf Rieß et al. · 2010 · Annals of Neurology
  56. Brain neutral lipids mass is increased in α‐synuclein gene‐ablated mice
    Gwendolyn Barceló‐Coblijn, Mikhail Y. Golovko, Isabelle Weinhofer, Johannes Berger, Eric J. Murphy · 2007 · Journal of Neurochemistry
  57. Polyunsaturated Fatty Acids Induce α-Synuclein-Related Pathogenic Changes in Neuronal Cells
    Karen Assayag, Evgenia Yakunin, Virginie Loeb, Dennis J. Selkoe, Ronit Sharon · 2007 · American Journal Of Pathology
  58. Activity‐dependent secretion of alpha‐synuclein by enteric neurons
    Sébastien Paillusson, Thomas Clairembault, Mandy Biraud, Michel Neunlist, Pascal Derkinderen · 2012 · Journal of Neurochemistry
  59. Interaction of α-synuclein with vesicles that mimic mitochondrial membranes
    Imola G. Zigoneanu, Yoo Jeong Yang, Alexander S. Krois, Md. Emdadul Haque, Gary J. Pielak · 2011 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  60. Phospholipase D1 Regulates Secretagogue-stimulated Insulin Release in Pancreatic β-Cells
    William E. Hughes, Zehra Elgundi, Ping Huang, Michael A. Frohman, Trevor J. Biden · 2004 · Journal of Biological Chemistry
  61. Structural Determinants of PLD2 Inhibition by α-Synuclein
    Jacqueline E. Payton, Richard J. Perrin, Wendy S. Woods, Julia M. George · 2004 · Journal of Molecular Biology
  62. Assessing the Subcellular Dynamics of Alpha-synuclein Using Photoactivation Microscopy
    Susana A. Gonçalves, Tiago F. Outeiro · 2013 · Molecular Neurobiology
  63. The structure of dopamine induced α-synuclein oligomers
    Agata Rekas, Robert B Knott, Anna V. Sokolova, Kevin Jeffrey Barnham, Keyla A. Perez, Colin Louis Masters, Simon C. Drew, Roberto Cappai, Cyril C. Curtain, Chi L.L. Pham · 2010 · European Biophysics Journal
  64. Dopamine quinones interact with α-synuclein to form unstructured adducts
    Marco Bisaglia, Laura Tosatto, Francesca Munari, Isabella Tessari, Patrizia Polverino de Laureto, Stefano Mammi, Luigi Bubacco · 2010 · Biochemical and Biophysical Research Communications
  65. Oligomeric α-synuclein inhibits tubulin polymerization
    Leo Chen, Jinghua Jin, Jeanne Davis, Yong Feng Zhou, Yan Wang, Jun Liu, Paul J. Lockhart, Jing Zhang · 2007 · Biochemical and Biophysical Research Communications
  66. Abnormal α-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease
    Esther Dalfó, Marta Barrachina, José Luís Rosa, Santiago Ambrosio, Isidró Ferrer · 2004 · Neurobiology of Disease
  67. α-Synuclein Can Inhibit SNARE-Mediated Vesicle Fusion through Direct Interactions with Lipid Bilayers
    David C. DeWitt, Elizabeth R. Rhoades · 2013 · Biochemistry
  68. Differential Expression and Distribution of α-, β-, and γ-Synuclein in the Developing Human Substantia Nigra
    James E. Galvin, Theresa Schuck, Virginia M.‐Y. Lee, John Q. Trojanowski · 2001 · Experimental Neurology
  69. Leucine-rich repeat kinase 2 induces α-synuclein expression via the extracellular signal-regulated kinase pathway
    Iria Carballo‐Carbajal, S. Weber-Endreß, Giorgio Rovelli, Diane Chan, Benjamin L. Wolozin, Christian L. Klein, Nadja Patenge, Thomas Gasser, Philipp J. Kahle · 2010 · Cellular Signalling
  70. β-synuclein modulates α-synuclein neurotoxicity by reducing α-synuclein protein expression
    Yuxin Fan, Pornprot Limprasert, Ian V.J. Murray, Annette C. Smith, Virginia M.‐Y. Lee, John Q. Trojanowski, Bryce L. Sopher, Albert R. La Spada · 2006 · Human Molecular Genetics
  71. Synuclein‐1 is selectively up‐regulated in response to nerve growth factor treatment in PC12 cells
    Leonidas Stefanis, Nikolai G. Kholodilov, Hardy J. Rideout, Robert E. Burke, Lloyd A. Greene · 2001 · Journal of Neurochemistry
  72. Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with α‐synuclein genotype
    Irit Rappley, David S. Myers, Stephen B Milne, Pavlina T. Ivanova, Matthew J. LaVoie, H. Alex Brown, Dennis J. Selkoe · 2009 · Journal of Neurochemistry
  73. Acyl-CoA Synthetase Activity Links Wild-Type but Not Mutant α-Synuclein to Brain Arachidonate Metabolism
    Mikhail Y. Golovko, Thad A. Rosenberger, Nils Joakim Færgeman, Søren Feddersen, Nelson B. Cole, Ingrid Pribill, Johannes Berger, Robert Luke Nussbaum, Eric J. Murphy · 2006 · Biochemistry
  74. Evidence that the blockade of mitochondrial respiration by the neurotoxin 1-methyl-4-phenylpyridinium (MPP+) involves binding at the same site as the respiratory inhibitor, rotenone
    Matthew J. Krueger, Thomas P. Singer, John E. Casida, Rona Ruth Ramsay · 1990 · Biochemical and Biophysical Research Communications
  75. Immunohistochemical comparison of α- and β-synuclein in adult rat central nervous system
    Fumiaki Mori, Kunikazu Tanji, Makoto Yoshimoto, Hitoshi Takahashi, Koichi Wakabayashi · 2002 · Brain Research
  76. Synuclein Gamma Inhibits the Mitotic Checkpoint Function and Promotes Chromosomal Instability of Breast Cancer Cells
    Satoru Inaba, Cong Li, Y. Eric Shi · 2005 · Breast Cancer Research and Treatment
  77. Subcellular localisation of recombinant α- and γ-synuclein
    Christian G. Specht, Cezar M. Tigaret, Georg F. Rast, Agnes Thalhammer, York Rudhard, Ralf Schoepfer · 2004 · Molecular and Cellular Neuroscience
  78. Conformation-specific Binding of α-Synuclein to Novel Protein Partners Detected by Phage Display and NMR Spectroscopy
    Wendy S. Woods, John M. Boettcher, Donghua H. Zhou, Kathryn D. Kloepper, Kevin L. Hartman, Daniel T. Ladror, Zhi Qi, Chad M. Rienstra, Julia M. George · 2007 · Journal of Biological Chemistry
  79. Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein
    Joel C. Watts, Kurt Giles, Jan Stöhr, Abby Oehler, Sumita Bhardwaj, Sunny K. Grillo, Smita S. Patel, Stephen J. DeArmond, Stanley B. Prusiner · 2012 · Proceedings of the National Academy of Sciences
  80. Alpha-synuclein transgenic mice display age-related slowing of gastrointestinal motility associated with transgene expression in the vagal system
    Ali Reza Noorian, Jennifer Rha, Dana M. Annerino, Douglas Bernhard, Georgia M. Taylor, James G. Greene · 2012 · Neurobiology of Disease
  81. Golgi fragmentation is Rab and SNARE dependent in cellular models of Parkinson’s disease
    Wilson O. Rendón, Emma Martínez‐Alonso, Mónica Tomás, Narcisa Martínez-Martínez, José A. Martínez‐Menárguez · 2012 · Histochemistry and Cell Biology
  82. α‐Synuclein gene ablation increases docosahexaenoic acid incorporation and turnover in brain phospholipids
    Mikhail Y. Golovko, Thad A. Rosenberger, Søren Feddersen, Nils Joakim Færgeman, Eric J. Murphy · 2007 · Journal of Neurochemistry
  83. A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain
    Masayo Fujita, Shuei Sugama, Kazunari Sekiyama, Akio Sekigawa, Tohru Tsukui, Masaaki Nakai, Masaaki Waragai, Takato Takenouchi, Yoshiki Takamatsu, Jianshe Wei et al. · 2010 · Nature Communications
  84. The effect of α‐synuclein knockdown on MPP+ toxicity in models of human neurons
    Timothy M. Fountaine, Lara Lourenço Venda, Nicholas Warrick, Helen Christian, Patrik Brundin, Keith M. Channon, Richard Wade‐Martins · 2008 · European Journal of Neuroscience
  85. Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the α-synuclein gene
    Keiji Yamaguchi, Elizabeth J. Cochran, Jill R. Murrell, Mihael H. Polymeropoulos, Kathleen M. Shannon, R. Anthony Crowther, Michel Goedert, Bernardino Francesco Ghetti · 2005 · Acta Neuropathologica
  86. Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation
    Bobby Thomas, Allen S. Mandir, Neva C. West, Ying Liu, Shaida A. Andrabi, Wanda L.H. Stirling, Valina Lynn Dawson, Ted M. Dawson, Michael K. Lee · 2011 · PLoS ONE
  87. Abnormal compartmentalization of norepinephrine in mouse dentate gyrus in α‐synuclein knockout and A30P transgenic mice
    Leonid Yavich, Pekka Jäkälä, Heikki Tanila · 2006 · Journal of Neurochemistry
  88. α-Synuclein Oligomers with Broken Helical Conformation Form Lipoprotein Nanoparticles
    Jobin Varkey, Naoko Mizuno, Balachandra Gajanan Hegde, Naiqian Cheng, Alasdair C. Steven, Ralf Langen · 2013 · Journal of Biological Chemistry
  89. The mode of α-synuclein binding to membranes depends on lipid composition and lipid to protein ratio
    Volodymyr V. Shvadchak, Dmytro A. Yushchenko, Roberta Pievo, Thomas M. Jovin · 2011 · FEBS Letters
  90. Association of α-, β-, and γ-Synuclein With Diffuse Lewy Body Disease
    Kenya Nishioka, Christian W. Wider, Carles Vilariño‐Güell, Alexandra I. Soto‐Ortolaza, Sarah Lincoln, Jennifer M. Kachergus, Barbara Jasińska‐Myga, Owen A. Ross, Alex H. Rajput, Christopher A. Robinson et al. · 2010 · Archives of Neurology
  91. Heredity in multiple system atrophy
    Hiroyuki Soma, Ichiro Yabe, Asako Takei, Naoto Fujiki, Tetsuro Yanagihara, Hidenao Sasaki · 2005 · Journal of the Neurological Sciences
  92. β‐synuclein aggregates and induces neurodegeneration in dopaminergic neurons
    Grit Taschenberger, Johan Tolö, Julia Tereshchenko, Jasper Akerboom, Pauline Wales, Roland Benz, Stefan Becker, Tiago F. Outeiro, Loren L. Looger, Mathias Bähr et al. · 2013 · Annals of Neurology
  93. Subcellular localization of α-synuclein in primary neuronal cultures: effect of missense mutations
    Pamela J. McLean, Scott A. Ribich, Bradley T. Hyman · 2000 · Springer eBooks
  94. GLUCOCEREBROSIDASE MUTATIONS IN 108 NEUROPATHOLOGICALLY CONFIRMED CASES OF MULTIPLE SYSTEM ATROPHY
    Badmavady Segarane, Abi Li, Reema Paudel, Sonja W. Scholz, J. Neumann, Andrew John Lees, Tamás Révész, John Hardy, Christopher J. Mathias, Nicholas William Wood et al. · 2009 · Neurology
  95. Solid-State 13C NMR Reveals Annealing of Raft-Like Membranes Containing Cholesterol by the Intrinsically Disordered Protein α-Synuclein
    Avigdor Leftin, Constantin Job, Klaus Beyer, Michael F. Brown · 2013 · Journal of Molecular Biology
  96. Juvenile-onset generalized neuroaxonal dystrophy (Hallervorden-Spatz disease) with diffuse neurofibrillary and Lewy body pathology
    Koichi Wakabayashi, Takeshi Fukushima, Reiji Koide, Y. Horikawa, Masato Hasegawa, Yumiko Watanabe, T. Noda, I. Eguchi, Takashi Morita, M. Yoshimoto et al. · 2000 · Acta Neuropathologica
  97. In Vivo Imaging of α-Synuclein in Mouse Cortex Demonstrates Stable Expression and Differential Subcellular Compartment Mobility
    Vivek K. Unni, Tamily A. Weissman, Edward M. Rockenstein, Eliezer Masliah, Pamela J. McLean, Bradley T. Hyman · 2010 · PLoS ONE
  98. Distribution of α‐ and γ‐synucleins in the adult rat brain and their modification by high‐dose cocaine treatment
    Maria S. Brenz Verca, Amine Bahí, Frédéric Boyer, George C. Wagner, Jean‐Luc Dreyer · 2003 · European Journal of Neuroscience
  99. Synuclein accumulation is associated with cell‐specific neuronal death after spinal cord injury
    David J. Busch, Jennifer R. Morgan · 2011 · The Journal of Comparative Neurology
  100. Differential up-regulation of striatal dopamine transporter and α-synuclein by the pyrethroid insecticide permethrin
    J Gillette · 2003 · Toxicology and Applied Pharmacology
  101. Characteristics of alpha-synucleinopathy in centenarians
    Zheng‐Tong Ding, Yin Wang, Yuping Jiang, Yoshio Hashizume, Mari Yoshida, Maya Mimuro, Toshiaki Inagaki, Tamaki Iwase · 2006 · Acta Neuropathologica
  102. Human α-synuclein modulates vesicle trafficking through its interaction with prenylated Rab acceptor protein 1
    Hak Joo Lee, Shin Jung Kang, Kyunghee Lee, Hana Im · 2011 · Biochemical and Biophysical Research Communications
  103. The -synuclein gene in multiple system atrophy
    Tetsutaro Ozawa · 2006 · Journal of Neurology Neurosurgery & Psychiatry
  104. Regulation of α‐synuclein by bFGF in cultured ventral midbrain dopaminergic neurons
    Hardy J. Rideout, Paula Dietrich, Magali Savalle, William T. Dauer, Leonidas Stefanis · 2003 · Journal of Neurochemistry
  105. Glucosidase-beta variations and Lewy body disorders
    Matthew James Farrer, Lindsey N. Williams, Avi A. Algom, Jennifer M. Kachergus, Mary Hulihan, Owen A. Ross, Alex H. Rajput, Spiridon Papapetropoulos, Deborah C. Mash, Dennis W. Dickson · 2008 · Parkinsonism & Related Disorders
  106. Localization of α-, β-, and γ-synuclein during neuronal development and alterations associated with the neuronal response to axonal trauma
    Marian C. Quilty · 2003 · Experimental Neurology
  107. Signalling role for ARF and phospholipase D in mast cell exocytosis stimulated by crosslinking of the high affinity FcεR1 receptor
    Shamshad Cockcroft, Gemma Way, Niamh O’LUANAIGH, Raúl Pardo, Elisabet Sarri, Amanda C. Fensome · 2002 · Molecular Immunology
  108. Contrasting Effects of α-Synuclein and γ-Synuclein on the Phenotype of Cysteine String Protein α (CSPα) Null Mutant Mice Suggest Distinct Function of these Proteins in Neuronal Synapses
    Natalia N. Ninkina, Owen M. Peters, Natalie Connor‐Robson · 2012 · Journal of Biological Chemistry
  109. Evidence That α-Synuclein Does Not Inhibit Phospholipase D
    Irit Rappley, Aaron D. Gitler, Paige E. Selvy, Matthew J. LaVoie, Bruce David Levy, H. Alex Brown, Susan Lee Lindquist, Dennis J. Selkoe · 2009 · Biochemistry
  110. Increased lipolysis and altered lipid homeostasis protect γ-synuclein–null mutant mice from diet-induced obesity
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  111. Impairment of microtubule system increases α-synuclein aggregation and toxicity
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  112. Membrane bound α‐synuclein is fully embedded in the lipid bilayer while segments with higher flexibility remain
    Jonas Wietek, Ivan Haralampiev, Aouefa Amoussouvi · 2013 · FEBS Letters
  113. Compartmental loss of striatal medium spiny neurons in multiple system atrophy of parkinsonian type
    Kenta Sato, Ryuji Kaji, Sadayuki Matsumoto, Shinji Nagahiro, Satoshi Goto · 2007 · Movement Disorders
  114. Atypical parkinsonism with apraxia and supranuclear gaze abnormalities in type 1 Gaucher disease. Expanding the spectrum: Case report and literature review
    Araceli Alonso Cánovas, Petra Katschnig, Arianna Tucci · 2010 · Movement Disorders
  115. Lipid Classes and Fatty Acid Patterns are Altered in the Brain of γ‐Synuclein Null Mutant Mice
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  116. Up‐regulation of gamma‐synuclein contributes to cancer cell survival under endoplasmic reticulum stress
    Hui Hua, Li Xu, Jiao Wang, Jing Jing, Ting L. Luo, Yangfu Jiang · 2008 · The Journal of Pathology
  117. Membrane-Induced Folding of the cAMP-Regulated Phosphoprotein Endosulfine-α
    John M. Boettcher, Kevin L. Hartman, Daniel T. Ladror · 2008 · Biochemistry
  118. Untitled work
    Goodrum · 2000 · 10.1002/(sici)1097-4547(20000215)59:4