Neurofilament Light: A Dynamic Cross-Disease Fluid Biomarker for Neurodegeneration
Open accessAbstract
In the current issue of Neuron, Bacioglu, Maia, and colleagues show that neurofilament light concentrations in body fluids reflect pathology and symptoms in mouse models of cerebral proteopathies and that these findings translate to human disease (Bacioglu et al., 2016).
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
CSF NFL increased either in parallel or prior to Aβ accumulation in the mouse model of AD.
“CSF NFL increased either in parallel or prior to Ab accumulation in the mouse model of AD (Zetterberg, 2016).”
From Disrupted structural connectivity in ArcAβ mouse model of Aβ amyloidosis (2020) · cites this paper as Zetterberg, 2016
The citation lists haven’t been fetched yet
References 11 · Cited by 197
- Authors
- Zetterberg, H.
- Affiliations
- Sahlgrenska University Hospital (SE)
- Corresponding author
- Zetterberg, Henrik
- ORCID
- Zetterberg, Henrik
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2016-07
- Volume
- 91
- Issue
- 1
- Pages
- 1-3
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2469997639
- Cited by
- 197
- References
- 11
- Citations by year
- 2026: 8 · 2025: 20 · 2024: 11 · 2023: 19 · 2022: 16 · 2021: 28 · 2020: 26 · 2019: 23 · 2018: 22 · 2017: 17 · 2016: 7
- FWCI
- 18.50
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Neurology › Amyotrophic Lateral Sclerosis Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Hereditary Neurological Disorders
- Keywords
- neurofilament light chain, neurodegeneration, fluid biomarkers, mouse model, cerebrospinal fluid
- MeSH terms
- Animals, Axons, Enzyme-Linked Immunosorbent Assay, Humans, Intermediate Filaments, Neurons, Biomarkers, Neurofilament Proteins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
