Planning, decision-making and the COMT rs4818 polymorphism in healthy males

Roussos, Panos; Giakoumaki, Stella G.; Pavlakis, Stefanos; Bitsios, Panos

doi:10.1016/j.neuropsychologia.2007.10.009

Planning, decision-making and the COMT rs4818 polymorphism in healthy males

Recent evidence suggests that a synonymous polymorphism within the COMT gene (rs4818 C/G) accounts for a greater variation of COMT activity compared to the functional Val158Met polymorphism. This is the first study on the effects of the rs4818 C/G polymorphism on cognition. One hundred and seven …