Metformin Effects on the Heart and the Cardiovascular System: A Review of Experimental and Clinical Data

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1. Additional file 1 of Effect of metformin on left ventricular mass and functional parameters in non-diabetic patients: a meta-analysis of randomized clinical trials
   Kamel, Ahmed M., Nirmeen Ahmed Sabry, Farid, Samar · 2022 · Figshare
2. Additional file 1 of High fat-induced inflammation in vascular endothelium can be improved by Abelmoschus esculentus and metformin via increasing the expressions of miR-146a and miR-155
   Luoning Gou, Liu, Geng, Ma, Rong, Anita Regmi, Zeng, Tianshu, Zheng, Juan, Xueyu Zhong, Chen, Lulu · 2020 · Figshare
3. Additional file 1 of Effects of GLP-1 receptor agonists and SGLT-2 inhibitors on cardiac structure and function: a narrative review of clinical evidence
   Natali, Andrea, Lorenzo Nesti, Tricò, Domenico, Ele Ferrannini · 2021 · Figshare
4. Additional file 1 of Metformin activated AMPK signaling contributes to the alleviation of LPS-induced inflammatory responses in bovine mammary epithelial cells
   Xu, Tianle, Wu, Xinyue, Xubin Lu, Liang, Yusheng, Mao, Yongjiang, Juan J. Loor, Yang, Zhangping · 2021 · Figshare
5. Additional file 2 of Effect of metformin on left ventricular mass and functional parameters in non-diabetic patients: a meta-analysis of randomized clinical trials
   Kamel, Ahmed M., Nirmeen Ahmed Sabry, Farid, Samar · 2022 · Figshare
6. Additional file 3 of Effect of metformin on left ventricular mass and functional parameters in non-diabetic patients: a meta-analysis of randomized clinical trials
   Kamel, Ahmed M., Nirmeen Ahmed Sabry, Farid, Samar · 2022 · Figshare
7. Effet protecteur du préconditionnement pharmacologique vis-à-vis de l’ischémie-reperfusion myocardique : Approche mécanistique et clinique
   Romain Rozier · 2021
8. Effects of metformin on CCl4-induced pulmonary fibrosis via autophagy pathway in rats: a histological, electron microscopic, and immunohistochemical study
   Fatma Y. Meligy, Amal T. Abou Elghait, Nessren M. Abd el‐Rady, Amira A. Kamel, Fatma K. Gameaa · 2026 · Ultrastructural Pathology
9. An eye on metformin: Applications and drug delivery strategies for ocular conditions
   Varaprasad R Regu, Bharat Bhusan Subudhi · 2026 · International Journal of Pharmaceutics
10. Impact of Metformin on Healthspan-Related Outcomes and Incidence of Diseases of Aging in People with Type 2 Diabetes Mellitus: A Systematic Review
    Amy Hai Yan Chan, Kebede Abera Beyene, Bertha Lai, Sarah Kim, Ivy Wu, Rana Al-Jawadi, Margaret Wu, Holly Foot, Gary Cheung, Xaviour J. Walker et al. · 2026 · Rejuvenation Research
11. Sex- and stressor-dependent effects of metformin on cardiac fibrosis in plasminogen activator inhibitor-1 deficiency
    Serena M. Pulente, Claire Fong-McMaster, Natasha A. Trzaskalski, Ernest Ngou, Yena Oh, Sora Kwon, Ella G. Stoppenbrink, Manuel Sebastian, Teagan Haggerty, Ishika Tripathi et al. · 2026 · Journal of Molecular and Cellular Cardiology