Oral Ang-(1-7) treatment improves white adipose tissue remodeling and hypertension in rats with metabolic syndrome

Barbosa, Maria Andréa; de Sousa, Graziele Galdino; de Castro, Uberdan Guilherme Mendes; Carneiro, Cláudia Martins; Figueiredo, Vivian Paulino; Guerra de Sá, Renata; Santos, Robson Augusto Souza dos; Alzamora, Andréia Carvalho

doi:10.1016/j.nutx.2019.100004

Oral Ang-(1-7) treatment improves white adipose tissue remodeling and hypertension in rats with metabolic syndrome

OBJECTIVE Angiotensin (Ang)-(1-7) has preventive effects on metabolic syndrome (MetS). The aim of this study was to evaluate the therapeutic effect of oral Ang-(1-7) on mean arterial pressure (MAP), insulin resistance (IR), inflammatory process, and remodeling of white adipose tissue (WAT) in rat…