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Cited by 361

The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.

Medication-related osteonecrosis of the jaw: definition and best practice for prevention, diagnosis, and treatment

Open access
Nicolatou-Galitis, Ourania, Schiødt, Morten, Mendes, Rui Amaral, Ripamonti, Carla, Hope, Sally, Drudge-Coates, Lawrence, Niepel, Daniela, Van den Wyngaert, Tim·2019·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Abstract

Skeletal complications caused by osteoporosis or bone metastases are associated with considerable pain, increased mortality, and reduced quality of life. Furthermore, such events place a burden on health care resources. Agents that prevent bone resorption, such as bisphosphonates or denosumab, can reduce the risk of skeletal-related events and are widely used in patients with osteoporosis or bone metastases of cancer. Medication-related osteonecrosis of the jaw (MRONJ) is a rare, but potentially serious, adverse event associated with high cumulative doses of bisphosphonates or denosumab. However, MRONJ can be treated, and the likelihood of the development of this condition can be reduced through prophylactic dental care and the maintenance of good oral hygiene. Dentists, as part of a multiprofessional team, have a critical role in preventing MRONJ. This review describes the incidence and pathophysiology of MRONJ and provides guidance for dental practitioners with regard to the screening, prophylactic treatment, diagnosis, and management of patients with this condition.

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Metadata

Authors
Nicolatou-Galitis, O., Schiødt, M., Mendes, R. A., Ripamonti, C., Hope, S., Drudge-Coates, L., Niepel, D., & Van den Wyngaert, T.
Venue
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Publisher
Elsevier BV
Published
2019-02
Volume
127
Issue
2
Pages
117-135
ISSN
2212-4403 (ISSN-L)
OpenAlex
W2896174631
Cited by
361
References
108
FWCI
10.45
Type
journal article
Language
en
Open access
hybrid

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Nicolatou-Galitis, O., Schiødt, M., Mendes, R. A., Ripamonti, C., Hope, S., Drudge-Coates, L., Niepel, D., & Van den Wyngaert, T. (2019). Medication-related osteonecrosis of the jaw: definition and best practice for prevention, diagnosis, and treatment. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. https://doi.org/10.1016/j.oooo.2018.09.008

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.