Genetic Testing in Persons with Age-Related Macular Degeneration and the Use of the AREDS Supplements: To Test or Not to Test?
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The AREDS investigators could not replicate the reported association between CFH, ARMS2, and AREDS supplementation, concluding that no significant associations existed.
“The AREDS investigators reported that they could not replicate the findings, concluding that no significant associations existed [64,65].”
From Genetics and Age-Related Macular Degeneration: A Practical Review for Clinicians. (2024) · cites this paper as [65]
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References 5 · Cited by 61
- Authors
- Chew, E. Y., Klein, M. L., Clemons, T. E., Agrón, E., & Abecasis, G. R.
- Affiliations
- National Institutes of Health (US)
- Oregon Health & Science University (US)
- Emmes (United States) (US)
- University of Michigan (US)
- Corresponding author
- Chew, Emily Y.
- Venue
- Ophthalmology
- Publisher
- Elsevier BV
- Published
- 2015-01
- Volume
- 122
- Issue
- 1
- Pages
- 212-215
- ISSN
- 0161-6420 (ISSN-L)
- PMC
- PMC4277900
- OpenAlex
- W2041254877
- Cited by
- 61
- References
- 5
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 4 · 2022: 2 · 2021: 8 · 2020: 3 · 2019: 5 · 2018: 5 · 2017: 10 · 2016: 8 · 2015: 11 · 2014: 1
- FWCI
- 8.86
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Ophthalmology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Eye Institute (HHS-N0I-EY-0-2127, ZIAEY000489)
- Topics
- Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Nutrition, Genetics, and Disease
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinal Development and Disorders
- Keywords
- age-related macular degeneration, genetic testing, antioxidant vitamins, zinc supplementation, complement factor H, LOC387715, treatment response, intermediate AMD
- MeSH terms
- Antioxidants, Genetic Testing, Genotype, Humans, Macular Degeneration, Proteins, Complement Factor H, Zinc Compounds, Dietary Supplements, Polymorphism, Single Nucleotide
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