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Cited by 14Ocular Surface and Contact LensCorneal surgery and disordersOcular Infections and Treatments

The DOI matches its Crossref record.

Overnight corneal swelling with high and low powered silicone hydrogel lenses

Open access
Moezzi, Amir M., Fonn, Desmond, Varikooty, Jalaiah, Simpson, Trefford L.·2015·Journal of Optometry
DOI 10.1016/j.optom.2014.03.002PMC PMC4314620
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Abstract

PURPOSE: To compare central corneal swelling after eight hours of sleep in eyes wearing four different silicone hydrogel lenses with three different powers. METHODS: Twenty-nine neophyte subjects wore lotrafilcon A (Dk, 140), balafilcon A (Dk, 91), galyfilcon A (Dk, 60) and senofilcon A (Dk, 103) lenses in powers -3.00, -10.00 and +6.00 D on separate nights, in random order, and on one eye only. The contra-lateral eye (no lens) served as the control. Central corneal thickness was measured using a digital optical pachometer before lens insertion and immediately after lens removal on waking. RESULTS: For the +6.00 D and -10.00 D, lotrafilcon A induced the least swelling and galyfilcon A the most. The +6.00 D power, averaged across lens materials, induced significantly greater central swelling than the -10.00 and -3.00 D (Re-ANOVA, p<0.001), (7.7±2.9% vs. 6.8±2.8% and 6.5±2.5% respectively) but there was no difference between -10.00 and -3.00 D. Averaged for power, lotrafilcon A induced the least (6.2±2.8%) and galyfilcon A the most (7.6±3.0%) swelling at the center (Re-ANOVA, p<0.001). Central corneal swelling with +6.00 D was significantly greater than -10.00 D lens power despite similar levels of average lens transmissibility of these two lens powers. CONCLUSIONS: The differences in corneal swelling of the lens wearing eyes are consistent with the differences in oxygen transmission of the silicone hydrogel lenses. In silicone hydrogel lenses central corneal swelling is mainly driven by central lens oxygen transmissibility.

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Research works printed but not linked: 29

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Metadata

Authors
Moezzi, A. M., Fonn, D., Varikooty, J., & Simpson, T. L.
Affiliations
University of Waterloo (CA)
Corresponding author
Moezzi, Amir M.
ORCID
Venue
Journal of Optometry
Publisher
Elsevier BV
Published
2015-01
Volume
8
Issue
1
Pages
19-26
ISSN
1888-4296 (ISSN-L)
DOI
10.1016/j.optom.2014.03.002
PMC
PMC4314620
OpenAlex
W2106570134
Cited by
14
References
0
Citations by year
2023: 1 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 3 · 2015: 1
FWCI
1.33
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Optometry (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Ophthalmology › Ocular Surface and Contact Lens
  • Health Sciences › Medicine › Ophthalmology › Corneal surgery and disorders
  • Health Sciences › Medicine › Ophthalmology › Ocular Infections and Treatments
Keywords
silicone hydrogel contact lenses, corneal edema, overnight lens wear, lens power, lotrafilcon A, balafilcon A, senofilcon A, central corneal thickness, corneal oxygenation
MeSH terms
Adolescent, Adult, Analysis of Variance, Contact Lenses, Extended-Wear, Contact Lenses, Hydrophilic, Female, Humans, Male, Middle Aged, Silicone Elastomers, Corneal Edema, Hydrogels, Young Adult

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CoChat. (2026). Citation check: Overnight corneal swelling with high and low powered silicone hydrogel lenses. https://app.cochat.ai/papers/10.1016/j.optom.2014.03.002
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Moezzi, A. M., Fonn, D., Varikooty, J., & Simpson, T. L. (2015). Overnight corneal swelling with high and low powered silicone hydrogel lenses. Journal of Optometry. https://doi.org/10.1016/j.optom.2014.03.002

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