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Validity of the FACT-H&N (v 4.0) among Malaysian oral cancer patients
Abstract
To assess the cross-sectional construct validity of the Malay-translated and cross-culturally adapted FACT-H&N (v 4.0) for discriminative use in a sample of Malaysian oral cancer patients. A cross-sectional study of adults newly diagnosed with oral cancer. HRQOL data were collected using the FACT-H&N (v 4.0), a global question and a supplementary set of eight questions ('MAQ') obtained earlier in pilot work. Of the 76 participants (61.8% female; 23.7% younger than 50), most (96.1%) had oral squamous cell carcinoma; two-thirds were in Stages III or IV. At baseline, patients' mean FACT summary (FACT-G, FACT-H&N, FACT-H&N TOI, and FHNSI) and subscale (pwb, swb, ewb, fwb, and hnsc) scores were towards the higher end of the range. Equal proportions (36.8%) rated their overall HRQOL as 'good' or 'average'; fewer than one-quarter rated it as 'poor', and only two as 'very good'. All six FACT summary and most subscales had moderate-to-good internal consistency. For all summary scales, those with 'very poor/poor' self-rated HRQOL differed significantly from the 'good/very good' group. All FACT summary scales correlated strongly (r>0.75). Summary scales showed convergent validity (r>0.90) but little discriminant validity. The discriminant validity of the FHNSI improved with the addition of the MAQ. The FACT-H&N summary scales and most subscales demonstrated acceptable cross-sectional construct validity, reliability and discriminative ability, and thus appear appropriate for further use among Malaysian oral cancer patients.
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“FACT–H & N has been translated and validated among the Malaysian cancer patient population. All of its subscales have moderate to good internal consistency with Cronbach’s alphas ranging from 0.65 to 0.87 [59].”
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Zhang, Z., Leong Bin Abdullah, M. F. I., Shari, N. I., & Lu, P. (2022) · PLoS ONE · doi:10.1371/journal.pone.0267887 · Cited by 46
Metadata
- Authors
- Doss, J. G., Thomson, W. M., Drummond, B. K., & Raja Latifah, R. J.
- Affiliations
- University of Malaya (MY)
- University of Otago (NZ)
- Corresponding author
- Doss, J.G.
- Venue
- Oral Oncology
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 47
- Issue
- 7
- Pages
- 648-652
- ISSN
- 1368-8375 (ISSN-L)
- OpenAlex
- W2141450695
- Cited by
- 34
- References
- 17
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 5 · 2023: 1 · 2022: 3 · 2021: 1 · 2020: 5 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 3 · 2014: 2 · 2013: 2 · 2012: 1
- FWCI
- 0.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Oral Oncology (publishedVersion)
- PubMed (publishedVersion)
- The University of Malaya Research Repository (University of Malaya) (acceptedVersion)
- Funders
- University of Washington
- Universiti Malaya
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Otorhinolaryngology › Head and Neck Cancer Studies
- Health Sciences › Dentistry › General Dentistry › Oral health in cancer treatment
- Keywords
- FACT-H&N, oral cancer, oral squamous cell carcinoma, health-related quality of life, Malay translation, cross-cultural adaptation, construct validity, discriminant validity, Malaysian patients, FACT-G
- MeSH terms
- Adult, Aged, Aged, 80 and over, Carcinoma, Squamous Cell, Cross-Sectional Studies, Cross-Cultural Comparison, Female, Health Status, Humans, Language, Malaysia, Male, Middle Aged, Mouth Neoplasms, Quality of Life, Surveys and Questionnaires, Translations, Reproducibility of Results, Discriminant Analysis, Asian People, Young Adult, Diagnostic Self Evaluation
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