Intratympanic steroids for sensorineural hearing loss
Abstract
Corticosteroids are standard treatment for a number of inflammatory and immune-mediated inner ear diseases. In recent years there has been growing interest in intratympanic administration of steroids as a means of achieving high inner ear drug concentration and low risk of systemic side effects. Idiopathic sudden sensorineural hearing loss seems to be the condition with the greatest potential for both study and clinical use of intratympanic steroid treatment. Despite promising preliminary observations, there re-main many unanswered questions about this treatment modality.
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The population described herein likely benefited less from spontaneous recovery, which occurs within 14 days from symptom onset, and consequently had worse hearing recovery.
“The population described herein likely benefited less from spontaneous recovery, which occurs within 14 days from symptom onset, and as a consequence are associated with worse hearing recovery [14-17].”
From Intratympanic steroid administration and predictors of recovery in sudden sensorineural hearing loss (2025) · cites this paper as [15]
Spontaneous recovery occurs within 14 days from symptom onset.
“spontaneous recovery, which occurs within 14 days from symptom onset”
From Intratympanic steroid administration and predictors of recovery in sudden sensorineural hearing loss (2025) · cites this paper as [15]
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Intratympanic steroid administration and predictors of recovery in sudden sensorineural hearing loss
Kennedy, D. J., Williams, E., Wolf, L., Golden, J., Lana, A., Wiefels, M., Pyle, M., Yunis, V., & Hoffer, M. (2025) · PLOS One · doi:10.1371/journal.pone.0332809 · Cited by 4 · see citing works
- Authors
- Rauch, S. D.
- Affiliations
- Massachusetts Eye and Ear Infirmary (US)
- Corresponding author
- Rauch, Steven D.
- ORCID
- Rauch, Steven D.
- Venue
- Otolaryngologic Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2004-10
- Volume
- 37
- Issue
- 5
- Pages
- 1061-1074
- ISSN
- 0030-6665 (ISSN-L)
- OpenAlex
- W1971248169
- Cited by
- 88
- References
- 0
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2022: 1 · 2021: 6 · 2020: 4 · 2019: 3 · 2018: 1 · 2017: 3 · 2016: 4 · 2015: 7 · 2014: 7 · 2013: 7 · 2012: 7
- FWCI
- 1.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Otolaryngologic Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
- Keywords
- intratympanic corticosteroids, sensorineural hearing loss, idiopathic sudden sensorineural hearing loss, inner ear disorders, systemic side effects
- MeSH terms
- Administration, Oral, Administration, Topical, Glucocorticoids, Hearing Loss, Sensorineural, Humans, Tympanic Membrane, Treatment Outcome
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