The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.
Long-term maintenance of the analgesic effects of transcranial magnetic stimulation in fibromyalgia
Abstract
We assessed for the first time the long-term maintenance of repetitive transcranial magnetic stimulation (rTMS)-induced analgesia in patients with chronic widespread pain due to fibromyalgia. Forty consecutive patients were randomly assigned, in a double-blind fashion, to 2 groups: one receiving active rTMS (n=20) and the other, sham stimulation (n=20), applied to the left primary motor cortex. The stimulation protocol consisted of 14 sessions: an "induction phase" of 5 daily sessions followed by a "maintenance phase" of 3 sessions a week apart, 3 sessions a fortnight apart, and 3 sessions a month apart. The primary outcome was average pain intensity over the last 24 hours, measured before each stimulation from day 1 to week 21 and at week 25 (1 month after the last stimulation). Other outcomes measured included quality of life, mood and anxiety, and several parameters of motor cortical excitability. Thirty patients completed the study (14 in the sham stimulation group and 16 in the active stimulation group). Active rTMS significantly reduced pain intensity from day 5 to week 25. These analgesic effects were associated with a long-term improvement in items related to quality of life (including fatigue, morning tiredness, general activity, walking, and sleep) and were directly correlated with changes in intracortical inhibition. In conclusion, these results suggest that TMS may be a valuable and safe new therapeutic option in patients with fibromyalgia.
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Cited by
Rossini, P. M., Burke, D., Chen, R., Cohen, L. G., Daskalakis, Z., Di Iorio, R., Di Lazzaro, V., Ferreri, F., Fitzgerald, P. B., George, M. S., et al. (2015) · Clinical Neurophysiology · doi:10.1016/j.clinph.2015.02.001 · Cited by 2,753
Lefaucheur, J.-P., Aleman, A., Baeken, C., Benninger, D. H., Brunelin, J., Di Lazzaro, V., Filipović, S. R., Grefkes, C., Hasan, A., Hummel, F. C., et al. (2020) · Clinical Neurophysiology · doi:10.1016/j.clinph.2019.11.002 · Cited by 2,382
Lefaucheur, J.-P., André-Obadia, N., Antal, A., Ayache, S. S., Baeken, C., Benninger, D. H., Cantello, R. M., Cincotta, M., de Carvalho, M., De Ridder, D., et al. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2014.05.021 · Cited by 2,119
Non-invasive brain stimulation techniques for chronic pain
O'Connell, N. E., Wand, B. M., Marston, L., Spencer, S., & DeSouza, L. H. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008208.pub3 · Cited by 488
Fibromyalgia Syndrome: Etiology, Pathogenesis, Diagnosis, and Treatment
Bellato, E., Marini, E., Castoldi, F., Barbasetti, N., Mattei, L., Bonasia, D. E., & Blonna, D. (2012) · Pain Research and Treatment · doi:10.1155/2012/426130 · Cited by 389
Metadata
- Authors
- Mhalla, A., Baudic, S., de Andrade, D. C., Gautron, M., Perrot, S., Teixeira, M. J., Attal, N., & Bouhassira, D.
- Venue
- Pain
- Published
- 2011-07
- Volume
- 152
- Issue
- 7
- Pages
- 1478-1485
- ISSN
- 0304-3959 (ISSN-L)
- OpenAlex
- W2151011975
- Cited by
- 288
- References
- 62
- FWCI
- 9.77
- Type
- journal article
- Language
- en
- Open access
- closed
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