How many parkinsonian patients are suitable candidates for deep brain stimulation of subthalamic nucleus? Results of a questionnaire
Abstract
We used a CAPSIT-based questionnaire to estimate the percentage of parkinsonian patients suitable for subthalamic nucleus (STN) deep brain stimulation (DBS) in a movement disorders clinic. We found that out of 641 consecutive PD patients only 1.6% fulfilled strict STN-DBS criteria. When we applied more flexible criteria, the percentage of eligibility increased to 4.5%. Most patients (60%) were ineligible because they did not satisfy multiple questionnaire items. Items related to disease severity were responsible for the largest number of exclusions. This knowledge will help make decisions on resource allocation in centres wishing to start DBS surgery.
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The eligible patient rate for deep brain stimulation is extremely low, 1.6-4.5% in Parkinson's disease.
“and, besides, the eligible patient rate is extremely low (1.6–4.5% in PD) (38).”
From A Review on Wearable Technologies for Tremor Suppression (2021) · cites this paper as [38]
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“In general, the surgical outcomes of DBS therapy depend closely on multiple factors such as patient selection [7, 22], disease progression [23], surgical techniques particularly accurate targeting [18, 24], postoperative programming”
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“Approximately 5% of PD patients are candidates for deep brain stimulation (DBS) for motor symptoms [226].”
Functional neurosurgery in Parkinson’s disease in Russia
Tomskiy, A., Bril, E., Gamaleya, A., Fedorova, N., & Levin, O. S. (2019) · Annals of Clinical and Experimental Neurology · doi:10.25692/acen.2019.4.2 · Cited by 1
Deep Brain Stimulation for Parkinson Disease
Chou, K. L., Levin, E. L., Patil, P. G., & Leventhal, D. (2017) · Springer eBooks · doi:10.1007/978-3-319-28612-9_5 · Cited by 3 · see citing works
Volkmann, J. (2008) · CNS Spectrums · doi:10.1017/s1092852900017351 · Cited by 1 · see citing works
[Current possibilities of quality of life improvement in the late stages of Parkinson's disease].
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“[53], было продемонстрировано, что если строго следовать критериям включения СAPSIT-PD (Core Assesment Programm for Surgical Interventional Therapiesin PD), то только 1,6% пациентов, направленных в центр экстрапирамидных заболеваний для решения вопроса о применении DBS, соответствуют критериям использования этого мето…”
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МОЖЕТ ЛИ СТИМУЛЯЦИЯ СПИННОГО МОЗГА УЛУЧШИТЬ ПОХОДКУ ПРИ БОЛЕЗНИ ПАРКИНСОНА? УГЛУБЛЕННЫЙ ОБЗОР
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Self-citation
- Authors
- Morgante, L., Morgante, F., Moro, E., Epifanio, A., Girlanda, P., Ragonese, P., Antonini, A., Barone, P., Bonuccelli, U., Contarino, M. F., Capus, L., Ceravolo, M. G., Marconi, R., Ceravolo, R., D’Amelio, M., & Savettieri, G.
- Affiliations
- University of Messina (IT)
- University of Toronto (CA)
- University of Palermo (IT)
- Istituti Clinici di Perfezionamento (IT)
- University of Naples Federico II (IT)
- University of Pisa (IT)
- Università Cattolica del Sacro Cuore (IT)
- University of Trieste (IT)
- Marche Polytechnic University (IT)
- Ospedale Misericordia - Grosseto (IT)
- ORCID
- Venue
- Parkinsonism & Related Disorders
- Publisher
- Elsevier BV
- Published
- 2007-12
- Volume
- 13
- Issue
- 8
- Pages
- 528-531
- ISSN
- 1353-8020 (ISSN-L)
- OpenAlex
- W2164750863
- Cited by
- 94
- References
- 0
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 8 · 2023: 8 · 2022: 5 · 2021: 5 · 2020: 6 · 2019: 6 · 2018: 2 · 2017: 7 · 2016: 3 · 2015: 7 · 2014: 8 · 2013: 2 · 2012: 2
- FWCI
- 2.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Parkinsonism & Related Disorders (publishedVersion)
- PubMed (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion)
- Università Politecnica delle Marche (Università Politecnica delle Marche) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Padua Research Archive (University of Padova) (submittedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Neurology › Botulinum Toxin and Related Neurological Disorders
- Keywords
- Parkinson's disease, deep brain stimulation
- MeSH terms
- Adult, Aged, Female, Humans, Male, Middle Aged, Surveys and Questionnaires, Chi-Square Distribution, Patient Selection, Subthalamic Nucleus, Parkinsonian Disorders, Deep Brain Stimulation
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