Type 1 diabetes mellitus: etiology, presentation, and management
Abstract
This article reviews our current understanding of the etiology, presentation, and management of type 1 diabetes. The discussion includes a review of the natural history of diabetes, the complex relationship between genetic and environmental risk for type 1 diabetes, and current methods for prediction of type 1 diabetes. The article also reviews the current management of children who have new-onset type 1 diabetes, age-appropriate management goals, and diabetes complications. Finally, the article discusses the future of diabetes screening programs and the progress toward the ultimate goal of curing type 1 diabetes.
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Type 1 diabetes incidence is lower in adults than in children, although about one fourth of people with type 1 diabetes are diagnosed as adults.
“The incidence of T1D in adults is lower than in children, although approximately one fourth of persons with T1D are diagnosed as adults24.”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [24]
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References 92 · Cited by 211
- Authors
- Haller, M. J., Atkinson, M. A., & Schatz, D.
- Affiliations
- University of Florida Health (US)
- University of Florida (US)
- Venue
- Pediatric Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2005-12
- Volume
- 52
- Issue
- 6
- Pages
- 1553-1578
- ISSN
- 0031-3955 (ISSN-L)
- OpenAlex
- W1989391867
- Cited by
- 211
- References
- 92
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 13 · 2023: 14 · 2022: 15 · 2021: 6 · 2020: 4 · 2019: 7 · 2018: 11 · 2017: 7 · 2016: 12 · 2015: 13 · 2014: 11 · 2013: 14 · 2012: 19
- FWCI
- 0.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pediatric Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Keywords
- type 1 diabetes, etiology, genetic risk factors, environmental risk factors, natural history of diabetes, children, diabetes complications
- MeSH terms
- Insulin Glargine, Autoantibodies, Blood Glucose, Child, Diabetes Mellitus, Type 1, Humans, Hypoglycemia, Insulin, Diabetic Ketoacidosis, Genetic Predisposition to Disease, Nutrition Therapy, Diabetes Complications, Insulin, Long-Acting
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