Cited by 11Peripheral Neuropathies and DisordersAutoimmune Neurological Disorders and TreatmentsCardiovascular Syncope and Autonomic Disorders

Influenza A induced acute autonomic neuropathy in an adolescent

Lukkarinen, Heikki, Peltola, Ville·2010·Pediatric Neurology

Abstract

Influenza A may cause serious neurologic complications, but an autoimmune autonomic ganglionopathy has rarely been reported. Autoantibodies that impair synaptic transmission in the autonomic ganglia may cause orthostatic hypotension, gastrointestinal dysmotility, and sudomotor dysfunction. A 15-year-old girl developed severe and persisting orthostatic hypotension during influenza A infection. Removal of circulating antibodies by a single course of intravenous immunoglobulin resulted in rapid and complete recovery.

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Crossref · 10.1016/j.pediatrneurol.2010.06.011

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  • Several post-infectious syndromes have been described, including selective cholinergic dysautonomia with GI dysmotility after infectious mononucleosis (Epstein-Barr virus) or influenza A.

    “Several post-infectious syndromes have been described, including selective cholinergic dysautonomia with GI dysmotility after infectious mononucleosis (Epstein-Barr virus) or influenza A (Lukkarinen et al., 2010; Vassallo et al., 1991).”

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References 8 · Cited by 11

Authors
Lukkarinen, H., & Peltola, V.
Affiliations
Turku University Hospital (FI)
Corresponding author
Lukkarinen, Heikki
Venue
Pediatric Neurology
Publisher
Elsevier BV
Published
2010-12
Volume
43
Issue
6
Pages
425-426
ISSN
0887-8994 (ISSN-L)
OpenAlex
W2120144909
Cited by
11
References
8
Citations by year
2026: 1 · 2021: 2 · 2019: 1 · 2017: 1 · 2016: 1 · 2014: 1 · 2012: 2
FWCI
0.76
Type
journal article
Language
en
Open access
closed
Locations
  • Pediatric Neurology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Neurology › Peripheral Neuropathies and Disorders
  • Health Sciences › Medicine › Neurology › Autoimmune Neurological Disorders and Treatments
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
Keywords
influenza A virus, autoimmune autonomic ganglionopathy, autonomic neuropathy, orthostatic hypotension, autoantibodies, intravenous immunoglobulin, adolescents, sudomotor dysfunction, gastrointestinal motility disorders
MeSH terms
Adolescent, Autonomic Nervous System Diseases, Female, Ganglia, Autonomic, Humans, Influenza, Human, Influenza A virus, Immunoglobulins, Intravenous, Treatment Outcome

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