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Ovicidal and larvicidal activity and possible mode of action of phenylpropanoids and ketone identified in Syzygium aromaticum bud against Bradysia procera
Abstract
Bradysia procera is a serious insect pest of Panax ginseng plants. This study was conducted to determine the toxicity and mechanism of action of three phenylpropanoids, three terpenoids, and a ketone from Syzygium aromaticum bud methanol extract and hydrodistillate against third-instar larvae and eggs of B. procera. In a filter-paper mortality bioassay, methyl salicylate (LC 50, 5.26μg/cm 2) was the most toxic compound, followed by 2-nonanone, eugenol, and eugenyl acetate (8.77-15.40μg/cm 2). These compounds were significantly less toxic than either thiamethoxam, clothianidin, or cypermethrin. Egg hatching was inhibited by 97, 85, and 40% at 11.7μg/cm 2 of methyl salicylate, 2-nonanone, and eugenol, respectively. The egg-hatching inhibition of these insecticides was between 90 and 94% at 0.09μg/cm 2. These constituents were consistently more toxic in closed versus open containers, indicating that toxicity was achieved mainly through the action of vapor. The mechanism of larvicidal action of methyl salicylate, eugenol, and eugenyl acetate might be primarily due to interference with the octopaminergic system. 2-Heptyl acetate and 2-nonanone might act on both acetylcholinesterase and the octopaminergic receptor. 2-Heptanone might act primarily on acetylcholinesterase. Further studies will warrant possible applications of S. aromaticum bud-derived products as potential larvicides and ovicides for the control of B. procera.
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“The larvicidal action is mainly due to interference with the octopaminergic system [36].”
From Clove essential oil (Syzygium aromaticum L. Myrtaceae): Extraction, chemical composition, food applications, and essential bioactivity for human health (2021) · cites this paper as [36]
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Haro-González, J. N., Castillo-Herrera, G. A., Martínez-Velázquez, M., & Espinosa-Andrews, H. (2021) · Molecules · doi:10.3390/molecules26216387 · Cited by 463
Metadata
- Authors
- Hong, T.-K., Perumalsamy, H., Jang, K.-H., Na, E.-S., & Ahn, Y.-J.
- Affiliations
- Seoul National University (KR)
- Korea Ginseng Corporation (South Korea) (KR)
- Corresponding author
- Ahn, Young-Joon
- Venue
- Pesticide Biochemistry and Physiology
- Publisher
- Elsevier BV
- Published
- 2018-02
- Volume
- 145
- Pages
- 29-38
- ISSN
- 0048-3575 (ISSN-L)
- OpenAlex
- W2784236393
- Cited by
- 47
- References
- 61
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 5 · 2023: 4 · 2022: 8 · 2021: 7 · 2020: 3 · 2019: 9 · 2018: 1
- FWCI
- 4.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pesticide Biochemistry and Physiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education
- National Research Foundation of Korea
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Insect Pest Control Strategies
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect-Plant Interactions and Control
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect behavior and control techniques
- Keywords
- Syzygium aromaticum, phenylpropanoids, terpenoids, methyl salicylate, eugenol, eugenyl acetate, 2-nonanone, 2-heptanone, ovicidal activity, larvicidal activity, egg hatching inhibition, acetylcholinesterase, mechanism of action, botanical insecticides, vapor toxicity
- MeSH terms
- Acetylcholinesterase, Animals, Diptera, Insecticides, Ketones, Larva, Gas Chromatography-Mass Spectrometry, Oils, Volatile, Ovum, Phenylpropionates, Plant Extracts, Terpenes, Receptors, Biogenic Amine, Syzygium
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- The paper
- Hong, T.-K., Perumalsamy, H., Jang, K.-H., Na, E.-S., & Ahn, Y.-J. (2018). Ovicidal and larvicidal activity and possible mode of action of phenylpropanoids and ketone identified in Syzygium aromaticum bud against Bradysia procera. Pesticide Biochemistry and Physiology. https://doi.org/10.1016/j.pestbp.2018.01.003