Self-medication practice with analgesics (NSAIDs and acetaminophen), and antibiotics among nursing undergraduates in University College Farasan Campus, Jazan University, KSA
Open accessAbstract
Objective Self-medication practices are widely practiced globally as major form of self-care for pain management. Unfortunately, with COVID-19 pandemic, prescription only drugs are now increasingly being self-prescribed. Present study was therefore, conducted to generate data on self-medication practice with analgesics using non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen, and the antibiotics among nursing students of University College Farasan Campus. Materials and methods A cross-sectional descriptive study was conducted among 177 study participants (20±3 years) between December 2019 to February 2020 using questionnaire. Data analyses were done using origin software (6.1, Illinois, USA). Significance was considered at P<0.05. Study was conducted in Department of Nursing, University College Farasan Province, a premier educational institute of Farasan Island affiliated to Jazan university, KSA. Results Self-medication practices were high among nursing students (n=154 participants, 87%). Acetaminophen was highest used drug for analgesic purposes without prescriptions (n=101 participants, 57%). Among NSAIDs, Ibuprofen was most preferred for various analgesic purposes (n=35 participants, 20%) followed by diclofenac (n=9 participants, 5%) and meloxicam (n=5 participants, 3%). Azithromycine was the only antibiotic used by participants (n=4 participant, 2%). Most common causes of self-medication were headache (45%), menstrual pain (23%) and fever (14%). Main reason for self-medications was lack of time to consult doctor (68%). Furthermore, self-medication was significantly associated with study year (P<0.003). Conclusion Results give rise to concern for general well-being of future nursing workforce. There is need to implement educational actions and awareness programmes to limit self-medication practices among educated youth of this beautiful Island.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The drug classes most commonly self-medicated in India align with global patterns and support findings from preceding studies.
“aligning with global patterns and supporting findings from various preceding studies.2,34, 35, 36”
From Prevalence and patterns of self-medication practices in India: A systematic review and meta-analysis (2025) · cites this paper as [34]
The Introduction says NSAIDs and acetaminophen are the most frequently used drug groups for self-medication, and the Results report that acetaminophen was most common among the nursing undergraduates studied in Saudi Arabia. This supports the claimed alignment with preceding findings about analgesics, but the paper does not establish which drug classes are most commonly self-medicated in India or compare Indian findings with global patterns. (LLM, conf=0.84)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update
(2016) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2015.00052 · Cited by 744 · see citing works
Flagged first, then by citations
Research works printed but not linked: 44
- [2]Alia E. Grant-Kels J.M. Does Hydroxychloroquine combat COVID-19? A timeline of evidence J Am Acad Dermatol 83 1 2020 [e33–e34.2] PMC7151328 32283236
- [4]Dimabayo C.G. Mohammad E.K. Prevalence of self medication practice among nursing students in Jazan university, kingdom of Saudi Arabia IOSR J Nursing Health Sci (IOSR-JNHS) 5 2016 11 16 10.9790/1959-05151116 [Available from: www.iosrjournals.org] · DOI
- [6]Alshahrani S.M. Alavudeen S.S. Alakhali K.M. Self-medication among King Khalid university students, Saudi Arabia Risk Manag Health Care Pol 12 2019 243 249 PMC6861838 31814786
- [7]Al Essa M. Alshehri A. Alzahrani M. Practices, awareness and attitudes toward self-medication of analgesics among health sciences students in Riyadh, Saudi Arabia Saudi Pharm J 27 2 2019 235 239 10.1016/j.jsps.2018.11.004 30766435 PMC6362167 · DOI
- [8]Williams A. Crawford K. Self-medication practices among undergraduate nursing and midwifery students in Australia: a cross-sectional study Contemp Nurse 52 2016 410 420 10.1080/10376178.2016.1197782 27278099 · DOI
- [9]Gama A.S.M. Secoli S.R. Self-medication among nursing students in the state of Amazonas – Brazil Rev Gaucha Enferm 38 1 2017 e65111 28538809
- [11]Gras M. Champel V. Masmoudi K. Liabeuf S. Self-medication practices and their characteristics among French university students Clin Pharmacol 2020 10.1016/j.therap.2020.02.019 [Article in press] 32204933 · DOI
- [13]Abdu-Aguye S.N. Shehu A. Ahmad U.I. Management of musculoskeletal pain in retail drug outlets within a Nigerian community: a descriptive study Pharm Pract 15 2017 873 PMC5386622 28503221
- [15]Mercadante S.M.D. Alessandra Casuccio M.D. Antonio Agnello M.D. Salvatore Pumo M.D. Analgesic effects of non-steroidal anti-inflammatory drugs in cancer pain due to somatic or visceral mechanisms J Pain Symp Managt 17 1999 351 356 10355213
- [16]Pandit A. Sachdeva T. Bafna P. Drug-induced hepatotoxicity: a review J Appl Pharmaceut Sci 2 2012 233 239
- [17]Larkai E.N. Lacey Smith J. Lidsky M.D. Dyspepsia in NSAID users J Clin Gastroenterol 11 1989 158 162 2738358
- [18]Hirschowitz B.I. Non-steroidal anti-inflammatory drugs and the gastrointestinal tract Gastroenterologist 2 1994 207 223 7987619
- [19]Fries J.F. Miller S.R. Spitz P.W. Toward an epidemiology of gastropathy associated with non-steroidal anti-inflammatory drug use Gastroenterol 96 1989 647 655 2909442
- [20]Wongrakpanich S. Wongrakpanich A. Melhado K. A comprehensive review of non-steroidal anti-inflammatory drug use in the elderly Aging Dis 9 1 2018 143 150 29392089 PMC5772852
- [21]Bennett W.M. Henrich W.L. Stoff J.S. The renal effects of non-steroidal anti-inflammatory drugs: summary and recommendations Am J Kidney Dis 28 1996 S56 S62 8669431
- [22]Blowey D.L. Nephrotoxicity of over-the-counter analgesics, natural medicines, and illicit drugs Adoles Med Clin 16 2005 31 43 15844382
- [23]Murray M.D. Brater D.C. Renal toxicity of the non-steroidal anti-nflammatory drugs Annu Rev Pharmacol Toxicol 33 1993 435 465 8494347
- [24]Masubuchi Y. Yamada S. Horie T. Possible mechanisms of hepatocyte injury induced by diphenylamine and its structurally related NSAIDS J Pharmacol Exp Ther 292 2000 982 987 10688613
- [25]Boelsterli U.A. Mechanisms of NSAID-induced hepatotoxicity focus on nimesulide Drug Safety 25 2013 633 648 12137558
- [26]Wiliński J. Lechowicz M. Kameczura T. Non-steroidal anti-inflammatory drugs and paracetamol in self-therapy of various disorders in students of different fields of study Folia Med Cracov 55 2015 49 59 26839243
- [27]Siemionow K. Teul J. Dragowski P. New potential biomarkers of paracetamol-induced hepatotoxicity Adv Med Sci 61 2016 325 330 27471017
- [28]Hinson J.A. Roberts D.W. James L.P. Mechanisms of acetaminophen-induced liver necrosis Handb Exp Pharmacol 196 2010 369 405 10.1007/978-3-642-00663-0-12 PMC2836803 20020268 · DOI
- [29]Schiodt F.V. Rochling F.A. Casey D.L. Acetaminophen toxicity in an urban county hospital N Engl J Med 337 1997 1112 1117 9329933
- [30]Brand M.D. Affourtit C. Esteves T.C. Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins Free Radic Biol Med 37 2004 755 767 15304252
- [31]Bulera S.J. Cohen S.D. Khairallah E.A. Acetaminophen-arylated proteins are detected in hepatic subcellular fractions and numerous extra-hepatic tissues in CD-1 and C57B1/6J mice Toxicology 109 1996 85 99 8658549
- [32]Burcham P.C. Harman A.W. Acetaminophen toxicity results in site-specific mitochondrial damage in isolated mouse hepatocytes J Biol Chem 266 1991 5049 5054 2002047
- [33]Rotundo L. Pyrsopoulos N. Liver injury induced by paracetamol and challenges associated with intentional and unintentional use World J Hepatol 12 4 2020 125 136 32685105 PMC7336293
- [35]JaeSChke Williams C.D. Ramachandran Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity Liver Intl 32 2012 8 20 PMC3586825 21745276
- [38]Adnan M. Karim S. Khan S. Sabir A. Al-Banagi A.R.L. Jamal Q.M.S. Evaluation of self-medication practices and awareness among students in Al Qassim region of Saudi Arabia Clin Pharmacol Biopharmaceutics 4 2015 1 10.4172/2167-065X.1000133 · DOI
- [39]Ibrahim N.K. Alamoudi B.M. Baamer W.O. Al-Raddadi R.M. Self-medication with analgesics among medical students and interns in King Abdulaziz University, Jeddah, Saudi Arabia Pak J Med Sci 31 1 2015 14 18 10.12669/pjms.311.6526 25878607 PMC4386150 · DOI
- [40]Al Rasheed A. Yagoub A. Alkhashan H. Abdelhay O. Alawwad A. Al Aboud A. Prevalence and predictors of self-medication with antibiotics in Al Wazarat Health Center, Riyadh City, KSA BioMed Res Intl 2016 2016 1 8 PMC4736398 26881218
- [41]Albusalih F.A. Naqvi A.A. Ahmad R. Ahmad N. Prevalence of self-medication among students of pharmacy and medicine colleges of a public sector university in Dammam city, Saudi Arabia Pharmacy 5 2017 51 10.3390/pharmacy5030051 PMC5622363 28970463 · DOI
- [42]Alghamdi F. Al-Zahrani A. Alabdulaziz H. Dysmenorrhea characteristics and self-care method used among female nursing students at King Abdulaziz university J Gynecol Obs 7 2019 17 24 10.11648/j.jgo.20190701.13 · DOI
- [45]Khanam P. Haj-Ali D. Assessment of the knowledge and self-medication behaviours towards antibiotics among nursing students at King Saud Bin Abdulaziz university for health sciences Al Ahsa. J Nursing Care 6 2017 1 6 10.4172/2167-1168.100043 [431] · DOI
- [47]Dengler R. Roberts H. Adolescents’ use of prescribed drugs and over-the-counter preparations J Public Health 18 1996 437 442 10.1093/oxfordjournals.pubmed.a024542 9023803 · DOI
- [49]Khanam P. Haj-Ali D. Assessment of the knowledge and self-medication behaviours towards antibiotics among nursing students at king Saud Bin Abdulaziz university for health sciences, Al Ahsa J Nurs Care 6 2017 6 10.4172/2167-1168.1000431 · DOI
- [50]Horvat O. Tomas A. Kusturica M.P. Serbian students’ knowledge, attitudes and behaviour towards antibiotic use: is there room for improvement? Intl. J. Public Health 65 2020 1257 1267 10.2478/sjecr-2019-00551-7 32737562 · DOI
- [51]Ghumman S.S. Nadeem M. Nawaz A.J. Azeem M.U. Khan Z.H. Mazhar S.M. Self-management of headache: a cross-sectional survey in the General Public of Islamabad J Pak Med Assoc 63 2013 1210 1214 24601212
- [52]Twycross R. Pace V. Mihalyo M. Wilcock A. Acetaminophen (paracetamol) J Pain Symptom Manag 46 2013 747 755 24128822
- [53]Zardosht M. Dastoorpoor M. Bani Hashemi F. Khazaeli P. Prevalence and causes of self medication among medical students of Kerman university of medical sciences, Kerman, Iran Global J Health Sci 8 11 2016 149 159 10.5539/gjhs.v8n11p150 · DOI
- [54]Alam N. Saffoon N. Riaz U. Self-medication among medical and pharmacy students in Bangladesh BMC Res Notes 8 2015 763 10.1186/s13104-015-1737-0 26652176 PMC4675016 · DOI
- [56]Bally M. Beauchamp M.E. Abrahamowicz M. Nadeau L. Brophy J.M. Risk of acute myocardial infarction with real-world NSAIDs depends on dose and timing of exposure Pharmacoepidemiol Drug Safety 27 1 2018 69 77 10.1002/pds.4358 29171096 · DOI
- [57]Tariq M. Din F.U. Poor knowledge of university students regarding paracetamol: a wakeup call for public healthcare practitioners Cogent Med 4 2017 1 12 10.1080/2331205X.2017.1320848 · DOI
- [58]Jalan R. Williams R. Bernuau J. Paracetamol: are therapeutic doses entirely safe? Lancet 368 2007 2195 2196 17189017
Cited by
Sorted by citations
Prevalence and patterns of self-medication practices in India: A systematic review and meta-analysis
Chaudhary, V., Kumari, S., Sharma, B., Ahuja, C., Kishore, H., & Pal, B. (2025) · Medical Journal Armed Forces India · doi:10.1016/j.mjafi.2024.11.008 · Cited by 11 · see citing works
- Authors
- Faqihi, A. H. M. A., & Sayed, S. F.
- Affiliations
- Jazan University (SA)
- Corresponding author
- Sayed, S.F.
- ORCID
- Sayed, S.F.
- Venue
- Annales Pharmaceutiques Françaises
- Publisher
- Elsevier BV
- Published
- 2021-05
- Volume
- 79
- Issue
- 3
- Pages
- 275-285
- ISSN
- 0003-4509 (ISSN-L)
- PMC
- PMC7577276
- OpenAlex
- W3093654999
- Cited by
- 87
- References
- 1
- Citations by year
- 2026: 9 · 2025: 13 · 2024: 15 · 2023: 20 · 2022: 24 · 2021: 6
- FWCI
- 7.44
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annales Pharmaceutiques Françaises (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Jazan University
- Topics
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antibiotic Use and Resistance
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Keywords
- self-medication, analgesics, nonsteroidal anti-inflammatory drugs, paracetamol, ibuprofen, diclofenac, meloxicam, antibiotics, azithromycin, nursing students, pain management, headache, dysmenorrhea, fever, Farasan Islands
- MeSH terms
- Acetaminophen, COVID-19, Adolescent, Anti-Inflammatory Agents, Non-Steroidal, Anti-Bacterial Agents, Cross-Sectional Studies, Female, Humans, Male, Surveys and Questionnaires, Saudi Arabia, Self Medication, Students, Nursing, Universities, Analgesics, Non-Narcotic, Prescription Drugs, Young Adult, Pandemics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review