Role of orexin/hypocretin in reward-seeking and addiction: Implications for obesity

Cason, Angie M., Smith, Rachel J., Tahsili-Fahadan, Pouya, Moorman, David E., Sartor, Gregory C., Aston-Jones, Gary·2010·Physiology & Behavior

Cited by (229)

Items 101–200 of 229

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  7. Fructose:Glucose Ratios—A Study of Sugar Self-Administration and Associated Neural and Physiological Responses in the Rat
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  8. Age-specific treatment effects of orexin/hypocretin-receptor antagonism on methamphetamine-seeking behavior
    Natalie E. Zlebnik, Nathan A. Holtz, Victoria C. Lepak, Amy T. Saykao, Yanan Zhang, Marilyn E. Carroll · 2021 · Drug and Alcohol Dependence
  9. Mechanism of opioid addiction and its intervention therapy: Focusing on the reward circuitry and mu‐opioid receptor
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  10. Hypothalamic Responses to Cocaine and Food Cues in Individuals with Cocaine Dependence
    Sheng Zhang, Simon Zhornitsky, Thang M. Le, Chiang-Shan Ray Li · 2019 · The International Journal of Neuropsychopharmacology
  11. Role of intra-accumbal orexin receptors in the acquisition of morphine-induced conditioned place preference in the rats
    Mirmohammadali Mirramezani Alizamini, Zahra Farzinpour, Somayeh Ezzatpanah, Abbas Haghparast · 2017 · Neuroscience Letters
  12. The hypocretin/orexin system as a target for excessive motivation in alcohol use disorders
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    Xiaoning Liu, Shengli Gao, Nana Zhang, Tingting Jin, Xiangrong Sun, Xiao Luan, Luo Xu, Feifei Guo · 2020 · Neuropeptides
  14. Role of lateral hypothalamus in two aspects of attention in associative learning
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  15. Orexins (hypocretins) and energy balance: More than feeding
    Johan Fernø, Rosa María Señarís, Carlos Diéguez, Manuel Tena‐Sempere, Miguel López · 2015 · Molecular and Cellular Endocrinology
  16. Effect of suvorexant on event-related oscillations and EEG sleep in rats exposed to chronic intermittent ethanol vapor and protracted withdrawal
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  17. Overweight and obesity in childhood: Dietary, biochemical, inflammatory and lifestyle risk factors
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  19. Targeting the Orexin System for Prescription Opioid Use Disorder
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  20. Stimulatory role of the chemokine CCL2 in the migration and peptide expression of embryonic hypothalamic neurons
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  21. Food Addiction
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  22. Neuroanatomical Relationships between Orexin/Hypocretin-Containing Neurons/Nerve Fibers and Nicotine-Induced c-Fos-Activated Cells of the Reward-Addiction Neurocircuitry
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  23. Orexin/hypocretin receptor 1 signaling mediates Pavlovian cue-food conditioning and extinction
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  24. Intravenous prenatal nicotine exposure increases orexin expression in the lateral hypothalamus and orexin innervation of the ventral tegmental area in adult male rats
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  25. Orexin receptor 1 signaling contributes to ethanol binge-like drinking: Pharmacological and molecular evidence
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  26. Orexin in Patients with Alcohol Dependence Treated for Relapse Prevention: A Pilot Study
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  28. Suvorexant, an FDA-approved dual orexin receptor antagonist, reduces oxycodone self-administration and conditioned reinstatement in male and female rats
    Jessica M. Illenberger, Francisco J. Flores‐Ramirez, Alessandra Matzeu, Barbara J. Mason, Rémi Martin‐Fardon · 2023 · Frontiers in Pharmacology
  29. Differential importance of nucleus accumbens Ox1Rs and AMPARs for female and male mouse binge alcohol drinking
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  30. Area-specific analysis of the distribution of hypothalamic neurons projecting to the rat ventral tegmental area, with special reference to the GABAergic and glutamatergic efferents
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  33. SB-334867-A, a selective orexin-1 receptor antagonist, enhances taste aversion learning and blocks taste preference learning in rats
    Cristina Mediavilla, Victoria Cabello, Severiano Risco · 2011 · Pharmacology Biochemistry and Behavior
  34. Activation of lateral hypothalamic mGlu1 and mGlu5 receptors elicits feeding in rats
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    Derrick A. Dupré, Nestor Denys Tomycz, Michael Y. Oh, Donald M. Whiting · 2015 · Neurosurgical FOCUS
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    Alexandre Kisner, Julia E. Slocomb, Sarah Sarsfield, Maria Laura Zuccoli, Justin N. Siemian, Jay F. Gupta, Arvind Kumar, Yeka Aponte · 2018 · PLoS ONE
  39. Orexin and natural reward
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  40. Contribution of Dynorphin and Orexin Neuropeptide Systems to the Motivational Effects of Alcohol
    Rachel I. Anderson, David E. Moorman, Howard C. Becker · 2018 · Handbook of experimental pharmacology
  41. How Arousal-Related Neurotransmitter Systems Compensate for Age-Related Decline
    Mara Mather · 2020 · Cambridge University Press eBooks
  42. Palatable food self-administration and reinstatement are not affected by dual orexin receptor antagonism
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  43. Chronic Exposure to High Fat Diet Affects the Synaptic Transmission That Regulates the Dopamine Release in the Nucleus Accumbens of Adolescent Male Rats
    Wladimir Plaza-Briceño, Victoria B. Velásquez, Francisco Silva-Olivares, Karina Ceballo, Ricardo Céspedes, Gonzalo Jorquera, Gonzalo Cruz, Jonathan Martínez-Pinto, Christian Bonansco, Ramón Sotomayor‐Zárate · 2023 · International Journal of Molecular Sciences
  44. The darkness and the light: diurnal rodent models for seasonal affective disorder
    Anusha Shankar, Cory T. Williams · 2021 · Disease Models & Mechanisms
  45. The Role of Orexin-1 Receptors Within the Hippocampal CA1 Area in the Extinction and Reinstatement of Methamphetamine-Seeking Behaviors
    Ali Veisi, Hossein Khaleghzadeh‐Ahangar, Mojdeh Fattahi, Abbas Haghparast · 2022 · Neurochemical Research
  46. Neural activation patterns underlying basolateral amygdala influence on intra-accumbens opioid-driven consummatory versus appetitive high-fat feeding behaviors in the rat.
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  47. Activation of medial hypothalamic orexin neurons during a Go/No-Go task
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  48. Crosstalk between alcohol use disorder and obesity: two sides of the same coin?
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  49. Systemic Administration of Orexin a Loaded Liposomes Potentiates Nucleus Accumbens Shell Dopamine Release by Sucrose Feeding
    Francesco Lai, Flavia Cucca, Roberto Frau, Francesco Corrias, Michele Schlich, Pierluigi Caboni, Anna Maria Fadda, Valentina Bassareo · 2018 · Frontiers in Psychiatry
  50. Changes and overlapping distribution in the expression of CB1/OX1-GPCRs in rat hippocampus by kainic acid-induced status epilepticus
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  51. Progressive ratio responding in an obese mouse model: Effects of fenfluramine
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  52. Role of orexin peptide system in emotional overeating induced by brain reward stimulation in fed rats
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  54. Possible Mechanisms for the Effects of Orexin on Hippocampal Functioning and Spatial Learning (analytical review)
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  55. Do Orexins contribute to impulsivity-driven binge consumption of rewarding stimulus and transition to drug/food dependence?
    Manuel Alcaráz-Iborra, Inmaculada Cubero · 2015 · Pharmacology Biochemistry and Behavior
  56. PSPH-D-18-00526: Effect of a dual orexin receptor antagonist (DORA-12) on sleep and event-related oscillations in rats exposed to ethanol vapor during adolescence
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  57. Assessment of a proposed “three-criteria” cocaine addiction model for use in reinstatement studies with rats
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  58. VR Cue-Exposure Treatment For Bulimia Nervosa
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  60. The circadian neurobiology of reward
    Iwona Olejniczak, Kimberly Begemann, Ines Wilhelm, Henrik Oster · 2023 · Acta Physiologica
  61. Differential orexin/hypocretin expression in addiction-prone and -resistant rats selectively bred for high (HiS) and low (LoS) saccharin intake
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  62. Daily treatment with the dual orexin receptor antagonist DORA-12 during oxycodone abstinence decreases oxycodone conditioned reinstatement
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  63. Orexin A in the ventral tegmental area enhances saccharin-induced conditioned flavor preference: The role of D1 receptors in central nucleus of amygdala
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  64. Coordination of metabolism, arousal, and reward by orexin/hypocretin neurons
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  65. Reward-Seeking Behavior and Addiction: Cause or Cog?
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  67. Orexin-1 receptor antagonist in central nucleus of the amygdala attenuates the acquisition of flavor-taste preference in rats
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  80. Evaluation of the relationship between the gene expression level of orexin-1 receptor in the rat blood and prefrontal cortex, novelty-seeking, and proneness to methamphetamine dependence: A candidate biomarker
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