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Cited by 98Acute Ischemic Stroke ManagementInflammatory Biomarkers in Disease PrognosisLipoproteins and Cardiovascular Health

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

Monocyte/high-density lipoprotein ratio predicts the mortality in ischemic stroke patients

Bolayir, Asli, Gokce, Seyda Figul, Cigdem, Burhanettin, Bolayir, Hasan Ata, Yildiz, Ozlem Kayim, Bolayir, Ertugrul, Topaktas, Suat Ahmet·2018·Neurologia i Neurochirurgia Polska
DOI 10.1016/j.pjnns.2017.08.011
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Abstract

OBJECTIVE: The inflammatory process is a very important stage in the development and prognosis of acute ischemic stroke (AIS). The monocyte to high-density lipoprotein (HDL) ratio (MHR) is accepted as a novel marker for demonstrating inflammation. However, the role of MHR as a predictor of mortality in patients with AIS remains unclear. METHODS: We retrospectively enrolled 466 patients who were referred to our clinic within the first 24hours of symptom presentation and who were diagnosed with AIS between January 2008 and June 2016. Four hundred and eight controls of similar age and gender were also included. The patient group was classified into two groups according to 30-day mortality. The groups were compared in terms of monocyte counts, HDL, and MHR values. RESULTS: The patient group had significantly higher monocyte counts and lower HDL levels; therefore, this group had higher values of MHR compared to controls. Additionally, the monocyte count and MHR value were higher, and the HDL level was lower in non-surviving patients (p<0.001). The MHR value was also observed as a significant independent variable of 30-day mortality in patients with AIS (p<0.001). The optimum cut-off value of MHR in predicting the 30-day mortality for patients with AIS was 17.52 (95% CI 0.95-0.98). CONCLUSION: Our study demonstrated that a high MHR value is an independent predictor of 30-day mortality in patients with AIS.

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Metadata

Authors
Bolayir, A., Gokce, S. F., Cigdem, B., Bolayir, H. A., Yildiz, O. K., Bolayir, E., & Topaktas, S. A.
Affiliations
Sivas Cumhuriyet Üniversitesi (TR)
ORCID
Bolayir, Asli
Venue
Neurologia i Neurochirurgia Polska
Publisher
VM Media Group sp. z o.o
Published
2018-03
Volume
52
Issue
2
Pages
150-155
ISSN
0028-3843 (ISSN-L)
DOI
10.1016/j.pjnns.2017.08.011
OpenAlex
W2747790253
Cited by
98
References
27
Citations by year
2026: 7 · 2025: 5 · 2024: 6 · 2023: 13 · 2022: 13 · 2021: 17 · 2020: 24 · 2019: 5 · 2018: 8
FWCI
7.97
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Neurologia i Neurochirurgia Polska (publishedVersion)
  • PubMed (publishedVersion)
  • Via Medica Journals (submittedVersion)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
  • Health Sciences › Medicine › Oncology › Inflammatory Biomarkers in Disease Prognosis
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Keywords
acute ischemic stroke, monocyte-to-HDL cholesterol ratio, high-density lipoprotein, monocyte count, 30-day mortality, mortality prediction, inflammation, prognostic factors, cut-off values
MeSH terms
Brain Ischemia, Humans, Lipoproteins, HDL, Cholesterol, HDL, Monocytes, Retrospective Studies, Stroke

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CoChat. (2026). Citation check: Monocyte/high-density lipoprotein ratio predicts the mortality in ischemic stroke patients. https://app.cochat.ai/papers/10.1016/j.pjnns.2017.08.011
The paper
Bolayir, A., Gokce, S. F., Cigdem, B., Bolayir, H. A., Yildiz, O. K., Bolayir, E., & Topaktas, S. A. (2018). Monocyte/high-density lipoprotein ratio predicts the mortality in ischemic stroke patients. Neurologia i Neurochirurgia Polska. https://doi.org/10.1016/j.pjnns.2017.08.011