Hypercholesterolemia in Asperger syndrome: Independence from lifestyle, obsessive–compulsive behavior, and social anxiety
Abstract
We report on elevated total cholesterol and low-density lipoprotein (LDL) levels in 22 individuals with Asperger syndrome compared with well-matched controls, after accounting for lifestyle variables and clinical symptomatology that could affect them. A potential role for dyslipidemia in the pathogenesis of some forms of autism is discussed.
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Findings of lipid abnormalities have been inconsistent in reported ASD studies.
“Findings of lipid abnormalities have been inconsistent in reported ASD studies [56–59, 64], although this might be partially due to varying dietary intake in countries where the studies were performed.”
From Sterol and lipid analyses identifies hypolipidemia and apolipoprotein disorders in autism associated with adaptive functioning deficits (2021) · cites this paper as [64]
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References 21 · Cited by 52
- Authors
- Dziobek, I., Gold, S. M., Wolf, O. T., & Convit, A.
- Affiliations
- Bielefeld University (DE)
- New York University (US)
- Nathan Kline Institute for Psychiatric Research (US)
- Corresponding author
- Convit, Antonio
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2007-01
- Volume
- 149
- Issue
- 1-3
- Pages
- 321-324
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2019943612
- Cited by
- 52
- References
- 21
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 7 · 2022: 4 · 2021: 6 · 2020: 6 · 2019: 3 · 2018: 3 · 2017: 2 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 4 · 2012: 2
- FWCI
- 0.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- Max Planck Digital Library (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- National Center for Research Resources (M01 RR 00096, M01RR000096)
- NIH Clinical Center
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- Asperger syndrome, hypercholesterolemia, dyslipidemia, total cholesterol, low-density lipoprotein, obsessive-compulsive behavior, social anxiety, lifestyle factors, autism pathogenesis
- MeSH terms
- Adult, Cholesterol, Cognition Disorders, Demography, Female, Humans, Hydrocortisone, Hypercholesterolemia, Life Style, Male, Neuropsychological Tests, Obsessive-Compulsive Disorder, Phobic Disorders, Severity of Illness Index, Body Mass Index, Asperger Syndrome
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