Relationship between whole blood serotonin and repetitive behaviors in autism
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This study was conducted to examine the relationship between whole blood serotonin level and behavioral symptoms in 78 subjects with autism. No significant associations were found between serotonin level and the primary behavioral outcome measures. However, a significant inverse relationship between serotonin level and self-injury was demonstrated.
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Clinical correlates between hyperserotonemia and ASD-associated behaviors (e.g., stereotypy and self-injury) have been inconsistent.
“the clinical correlates between hyperserotonemia and ASD-associated behaviors (e.g., stereotypy and self-injury) have been inconsistent [36, 45–47].”
From Serotonin as a link between the gut-brain-microbiome axis in autism spectrum disorders (2018) · cites this paper as [47]
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References 16 · Cited by 50
- Authors
- Kolevzon, A., Newcorn, J. H., Kryzak, L., Chaplin, W., Watner, D., Hollander, E., Smith, C. J., Cook, E. H., & Silverman, J. M.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- St. John's University (US)
- Albert Einstein College of Medicine (US)
- Southwest Autism Research & Resource Center (US)
- University of Illinois Chicago (US)
- Corresponding author
- Kolevzon, Alexander
- ORCID
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2010-02
- Volume
- 175
- Issue
- 3
- Pages
- 274-276
- ISSN
- 0165-1781 (ISSN-L)
- PMC
- PMC2815211
- OpenAlex
- W2162925179
- Cited by
- 50
- References
- 16
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 4 · 2020: 1 · 2019: 6 · 2018: 1 · 2017: 3 · 2016: 3 · 2015: 5 · 2014: 4 · 2013: 9 · 2012: 3
- FWCI
- 1.29
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Eli Lilly and Company
- American Academy of Child and Adolescent Psychiatry
- U.S. Food and Drug Administration (FD-R-001520-01-03)
- National Institute of Mental Health (U54MH066673)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- autism spectrum disorder, serotonin, whole blood serotonin, repetitive behavior, self-harm, behavioral symptoms, biomarkers
- MeSH terms
- Adolescent, Autistic Disorder, Child, Child, Preschool, Female, Humans, Male, Psychiatric Status Rating Scales, Cumulative Trauma Disorders, Serotonin, Self-Injurious Behavior
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