The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Association of Y-linked variants with impulsivity and aggression in boys with attention-deficit/hyperactivity disorder of Chinese Han descent
Abstract
Y chromosome plays important role in brain function and may help to explain the sex difference in attention-deficit/hyperactivity disorder (ADHD). A total of 857 boys with ADHD and 574 male controls were genotyped for 14 Y-linked markers. Analyses for both dichotomous phenotype and quantitative traits and the interaction effects with MAOA were performed. The results indicated significant association of four markers (M88, M95, M175, and M119) with inhibition function and aggression in boys with ADHD. Positive interaction effects with MAOA were also detected. In conclusion, some Y-linked variants may be associated with the impulsivity and aggression in boys with ADHD.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Y-linked variants M175/DEL, M119/G showed higher 'Inhibit' score and aggression.
“Y-linked variants M175/DEL, M119/G showed higher ‘Inhibit’ score and aggression.”
From Genetics of child aggression, a systematic review (2024) · cites this paper as Liu [168]
Boys with MAOA rs1137070 T allele and the risk alleles of Y-linked markers (M88/G, M95/T, M175/DEL, and M119/G) showed the severest deficits in inhibition function and highest aggression behaviors.
“Boys with MAOA rs1137070 T allele and the risk alleles of Y-linked markers (M88/G, M95/T, M175/DEL, and M119/G) showed the severest deficits in inhibition function and highest aggression behaviors.”
From Genetics of child aggression, a systematic review (2024) · cites this paper as Liu [168]
Citations
Cites
Attention-deficit/hyperactivity disorder
Faraone, S. V., Asherson, P., Banaschewski, T., Biederman, J., Buitelaar, J. K., Ramos-Quiroga, J. A., Rohde, L. A., Sonuga-Barke, E. J. S., Tannock, R., & Franke, B. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.20 · Cited by 1,479
Flagged first, then by citations
Research works printed but not linked: 12
- Bogaert, 2011, Sexual orientation, fraternal birth order, and the maternal immune hypothesis: a review, Front. Neuroendocrinol., 32, 247, 10.1016/j.yfrne.2011.02.004 · DOI
- Davies, 2014, Sex differences in attention Deficit Hyperactivity Disorder: candidate genetic and endocrine mechanisms, Front. Neuroendocrinol., 35, 331, 10.1016/j.yfrne.2014.03.003 · DOI
- Dickey, 2012, The SHR Y chromosome increases cardiovascular, endocrine, and behavioral responses to stress compared to the WKY Y chromosome, Physiol. Behav., 106, 101, 10.1016/j.physbeh.2012.01.009 · DOI
- Gioia, 2000, Behavior rating inventory of executive function, Child Neuropsychol., 6, 235, 10.1076/chin.6.3.235.3152 · DOI · Paper page
- Kopsida, 2009, The role of the Y chromosome in brain function, Open Neuroendocrinol. J., 2, 20, 10.2174/1876528900902010020 · DOI
- Liu, 2011, Association analyses of MAOA in Chinese Han subjects with attention-deficit/hyperactivity disorder: family-based association test, case-control study, and quantitative traits of impulsivity, Am. J. Med. Genet. Part B: Neuropsychiatr. Genet., 156B, 737, 10.1002/ajmg.b.31217 · DOI
- Shah, 2009, Y haplogroups and aggressive behavior in a Pakistani ethnic group, Aggress. Behav., 35, 68, 10.1002/ab.20281 · DOI
- Su, 2006, Norm of ADHD diagnostic scale-Parent version in Chinese urban children, Zhong Guo Shi Yong Er Ke Za Zhi, 21, 833
- Trent, 2012, The influence of sex-linked genetic mechanisms on attention and impulsivity, Biol. Psychol., 89, 1, 10.1016/j.biopsycho.2011.09.011 · DOI
- Vawter, 2004, Gender-specific gene expression in post-mortem human brain: localization to sex chromosomes, Neuropsychopharmacology, 29, 373, 10.1038/sj.npp.1300337 · DOI
- Wu, 2009, Regulation of monoamine oxidase A by the SRY gene on the Y chromosome, Faseb J., 23, 4029, 10.1096/fj.09-139097 · DOI
- Xu, 2002, Sex differences in sex chromosome gene expression in mouse brain, Hum. Mol. Genet., 11, 1409, 10.1093/hmg/11.12.1409 · DOI
Cited by
Sorted by citations
Genetics of child aggression, a systematic review
Koyama, E., Kant, T., Takata, A., Kennedy, J. L., & Zai, C. C. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02870-7 · Cited by 33
Metadata
- Authors
- Liu, L., Cheng, J., Li, H., Su, Y., Sun, L., Yang, L., Qian, Q., & Wang, Y.
- Affiliations
- Peking University (CN)
- Corresponding author
- Qian, Qiujin
- Wang, Yufeng
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2017-06
- Volume
- 252
- Pages
- 185-187
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2589576929
- Cited by
- 10
- References
- 1
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2022: 2 · 2018: 4
- FWCI
- 0.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (81301171)
- National Basic Research Program of China (2014CB846104)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- attention deficit hyperactivity disorder, Y chromosome, impulsivity, aggression, inhibition, sex differences, monoamine oxidase A, gene-gene interaction
- MeSH terms
- Adolescent, Aggression, Attention Deficit Disorder with Hyperactivity, Child, China, Genotype, Humans, Impulsive Behavior, Male, Monoamine Oxidase, Phenotype, Genetic Variation, Case-Control Studies, Asian People, Genes, Y-Linked
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
