Recent life events and psychosis: The role of childhood adversities
Abstract
Life events are commonly reported to be related to psychosis. However, less attention has been given to the role that recent events play on psychosis, in relation to exposure to childhood adversity. The current study aimed to evaluate the relationship between recent events and psychosis, taking into account the role of early adversities. 78 psychotic patients and 156 controls were enrolled. Childhood adversity was evaluated using a validated semi-structured interview and the Childhood Experience of Care and Abuse Questionnaire. Recent events were recorded using a semi-structured interview with a normative and contextual approach. The diagnosis of psychosis was made according to Jablenski's criteria. Chi-square, t-test, odds ratio, and binary logistic regression statistical analyses were performed. Psychotic patients reported an excess of recent events. The occurrence of more than one recent event increased the risk of psychosis; there was a cumulative effect between recent and childhood events on psychosis. Recent events were significantly related to psychosis, even in the absence of childhood adversity or when adjusted for it. Our findings suggested that the effect of recent events on psychosis may be amplified by previous exposure to early adversity. Recent events alone, could be also linked to psychosis independently of childhood adversity.
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The development of psychosis appears to have a strong association with early life events.
“The development of psychosis appears to have a strong association with early life events (176).”
From Childhood Trauma, the HPA Axis and Psychiatric Illnesses: A Targeted Literature Synthesis (2022) · cites this paper as [176]
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Childhood Trauma, the HPA Axis and Psychiatric Illnesses: A Targeted Literature Synthesis
Murphy, F., Nasa, A., Cullinane, D., Raajakesary, K., Gazzaz, A., Sooknarine, V., Haines, M., Roman, E., Kelly, L., O'Neill, A., et al. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.748372 · Cited by 181 · see citing works
“The development of psychosis appears to have a strong association with early life events (176).”
Background
- Authors
- Mansueto, G., & Faravelli, C.
- Affiliations
- University of Florence (IT)
- Corresponding author
- Mansueto, Giovanni
- ORCID
- Mansueto, Giovanni
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2017-10
- Volume
- 256
- Pages
- 111-117
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2625458529
- Cited by
- 41
- References
- 12
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 6 · 2023: 3 · 2022: 5 · 2021: 3 · 2020: 7 · 2019: 5 · 2018: 8 · 2017: 2
- FWCI
- 7.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Florence Research (University of Florence) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- psychosis, recent life events, childhood adversity, cumulative adversity, psychosis risk factors, psychotic patients
- MeSH terms
- Adult, Child, Child Abuse, Cross-Sectional Studies, Female, Humans, Life Change Events, Male, Middle Aged, Psychotic Disorders, Surveys and Questionnaires
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