Salivary sex hormones in adolescent females with trichotillomania
Open accessAbstract
Trichotillomania is several times more common in women and has peak onset around puberty. The role of sex hormones, however, has received little research. 11 adolescent girls with trichotillomania, post-menarche and not taking birth control, were examined on a variety of clinical measures. Participants provided saliva samples for analysis of estradiol, progesterone, and testosterone levels. Lower progesterone was associated with more severe symptoms and lower levels of all hormones were associated with worse overall functioning. Adolescents with trichotillomania exhibit a range of hormone levels but that lower levels of certain hormones may have important clinical associations.
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In eleven adolescent girls with trichotillomania, lower levels of all hormones were associated with worse overall functioning.
“The recent study examining the role of sex hormones in eleven adolescent girls with trichotillomania found that lower progesterone was associated with more severe symptoms and lower levels of all hormones were associated with worse overall functioning.[28]”
From Trichotillomania (hair pulling disorder) (2019) · cites this paper as [28]
In eleven adolescent girls with trichotillomania, lower progesterone was associated with more severe symptoms.
“The recent study examining the role of sex hormones in eleven adolescent girls with trichotillomania found that lower progesterone was associated with more severe symptoms and lower levels of all hormones were associated with worse overall functioning.[28]”
From Trichotillomania (hair pulling disorder) (2019) · cites this paper as [28]
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References 25 · Cited by 9
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- Authors
- Grant, J. E., & Chamberlain, S. R.
- Affiliations
- University of Chicago (US)
- University of Cambridge (GB)
- Corresponding author
- Grant, Jon E.
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2018-07
- Volume
- 265
- Pages
- 221-223
- ISSN
- 0165-1781 (ISSN-L)
- PMC
- PMC5985958
- OpenAlex
- W2803051110
- Cited by
- 9
- References
- 25
- Citations by year
- 2026: 3 · 2025: 1 · 2022: 1 · 2020: 2 · 2019: 2
- FWCI
- 1.18
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Psychiatry Research (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- ePrints Soton (University of Southampton) (submittedVersion)
- Apollo (University of Cambridge) (submittedVersion, cc-by)
- Apollo (cc-by)
- Funders
- NIAAA
- Takeda Pharmaceuticals
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Urology › Hair Growth and Disorders
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Keywords
- trichotillomania, sex hormones, salivary hormones, estradiol, progesterone, testosterone, adolescent girls, puberty, symptom severity, functioning
- MeSH terms
- Adolescent, Child, Estradiol, Female, Humans, Progesterone, Saliva, Gonadal Steroid Hormones, Testosterone, Trichotillomania, Biomarkers
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