Genetics of cortisol secretion and depressive symptoms: A candidate gene and genome wide association approach

Velders, Fleur P.; Kuningas, Maris; Kumari, Meena; Dekker, Marieke J.; Uitterlinden, Andre G.; Kirschbaum, Clemens; Hek, Karin; Hofman, Albert; Verhulst, Frank C.; Kivimaki, Mika; Van Duijn, Cornelia M.; Walker, Brian R.; Tiemeier, Henning

doi:10.1016/j.psyneuen.2011.01.003

Genetics of cortisol secretion and depressive symptoms: A candidate gene and genome wide association approach

Summary Background Depressive patients often have altered cortisol secretion, but few studies have investigated genetic variants in relation to both cortisol secretion and depression. To identify genes related to both these conditions, we (1) tested the association of single nucleotide polymorphi…