Allostatic load and executive functions in overweight adults
Open accessPublished version of a preprint
Abstract
BACKGROUND/OBJECTIVE: Overweight is linked to inflammatory and neuroendocrine responses potentially prompting deregulations in biological systems harmful to the brain, particularly to the prefrontal cortex. This structure is crucial for executive performance, ultimately supervising behaviour. Thus, in the present work, we aimed to test the relationship between allostatic load increase, a surrogate of chronic physiological stress, and core executive functions, such as cognitive flexibility, inhibitory control, and working memory. METHOD: Forty-seven healthy-weight and 56 overweight volunteers aged from 21 to 40 underwent medical and neuropsychological examination. RESULTS: Overweight subjects exhibited a greater allostatic load index than healthy-weight individuals. Moreover, the allostatic load index was negatively related to inhibitory control. When separated, the link between allostatic load index and cognitive flexibility was more marked in the overweight group. CONCLUSIONS: An overweight status was linked to chronic physiological stress. The inverse relationship between the allostatic load index and cognitive flexibility proved stronger in this group. Set-shifting alterations could sustain rigid-like behaviours and attitudes towards food.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Higher levels of AL have been observed in higher weight individuals.
“Higher levels of AL (indexed by measures of blood pressure, C-reactive protein, fibrinogen, cholesterol ratio, triglycerides, and cortisol) have been observed in higher weight individuals [120].”
From Food Addiction and Psychosocial Adversity: Biological Embedding, Contextual Factors, and Public Health Implications (2020) · cites this paper as [120]
The citation lists haven’t been fetched yet
References 41 · Cited by 31
- Authors
- Ottino-González, J., Jurado, M. A., García-García, I., Caldú, X., Prats-Soteras, X., Tor, E., Sender-Palacios, M. J., & Garolera, M.
- Affiliations
- Hospital Sant Joan de Déu Barcelona (ES)
- Consorci Sanitari de Terrassa (ES)
- Hospital Terrassa (ES)
- Corresponding author
- Jurado, M.A.
- Venue
- Psychoneuroendocrinology
- Publisher
- Elsevier BV
- Published
- 2019-08
- Volume
- 106
- Pages
- 165-170
- ISSN
- 0306-4530 (ISSN-L)
- OpenAlex
- W2935817361
- Cited by
- 31
- References
- 41
- Citations by year
- 2025: 4 · 2024: 4 · 2023: 5 · 2022: 5 · 2021: 7 · 2020: 4 · 2019: 2
- FWCI
- 2.62
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Locations
- Psychoneuroendocrinology (publishedVersion)
- PubMed (publishedVersion)
- Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona) (submittedVersion, cc-by-nc-nd)
- PsyArXiv (OSF Preprints) (submittedVersion)
- PsyArXiv (OSF Preprints) (submittedVersion, cc-by)
- Funders
- Spanish Ministry of Economy, Industry and Competitiveness (PS2013-48045, PSI2017-86536)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Keywords
- allostatic load, executive function, overweight, chronic physiological stress, cognitive flexibility, inhibitory control, working memory, prefrontal cortex, set-shifting, food attitudes
- MeSH terms
- Adult, Body Weight, Brain, Cognition, Female, Humans, Male, Neurosecretory Systems, Spain, Overweight, Allostasis, Executive Function
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
