The DOI matches its Crossref record; 70 of the 71 references it cites were found in a registry or an index.
Does care at a cardiac arrest centre improve outcome after out-of-hospital cardiac arrest? – A systematic review
Open accessAbstract
Aim To perform a systematic review to answer 'In adults with attempted resuscitation after non-traumatic cardiac arrest does care at a specialised cardiac arrest centre (CAC) compared to care in a healthcare facility not designated as a specialised cardiac arrest centre improve patient outcomes?' Methods The PRISMA guidelines were followed. We searched bibliographic databases (Embase, MEDLINE and the Cochrane Library (CENTRAL)) from inception to 1st August 2018. Randomised controlled trials (RCTs) and non-randomised studies were eligible for inclusion. Two reviewers independently scrutinized studies for relevance, extracted data and assessed quality of studies. Risk of bias of studies and quality of evidence were assessed using ROBINS-I tool and GRADEpro respectively. Primary outcomes were survival to 30 days with favourable neurological outcomes and survival to hospital discharge with favourable neurological outcomes. Secondary outcomes were survival to 30 days, survival to hospital discharge and return of spontaneous circulation (ROSC) post-hospital arrival for patients with ongoing resuscitation. This systematic review was registered in PROSPERO (CRD 42018093369) RESULTS: We included data from 17 observational studies on out-of-hospital cardiac arrest (OHCA) patients in meta-analyses. Overall, the certainty of evidence was very low. Pooling data from only adjusted analyses, care at CAC was not associated with increased likelihood of survival to 30 days with favourable neurological outcome (OR 2.92, 95% CI 0.68-12.48) and survival to 30 days (OR 2.14, 95% CI 0.73-6.29) compared to care at other hospitals. Whereas patients cared for at CACs had improved survival to hospital discharge with favourable neurological outcomes (OR 2.22, 95% CI 1.74-2.84) and survival to hospital discharge (OR 1.85, 95% CI 1.46-2.34). Conclusions Very low certainty of evidence suggests that post-cardiac arrest care at CACs is associated with improved outcomes at hospital discharge. There remains a need for high quality data to fully elucidate the impact of CACs.
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“A key concern is that respondents may be systematically different to non-respondents. 310”
From European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions (2021) · cites this paper as [310]
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“The SPIIRT (Standard Protocol Items: Recommendations for Interventional Trials) PRO (Patient-reported outcome) extension guidelines provide information on including patient reported outcomes in clinical trials. 310”
From European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions (2021) · cites this paper as [310]
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Consenso Latinoamericano de Reanimación Cardiopulmonar
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Con: All Cardiac Arrest Patients Should Be Transferred to a Cardiac Arrest Center
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No-flow duration and outcomes in adult blunt traumatic out-of-hospital cardiac arrest
Kishihara, Y., Kashiura, M., Yasuda, H., Amagasa, S., Tamura, H., Nakajima, C., Shiraoka, Y., Okubo, M., Matsushima, K., & Moriya, T. (2026) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2026.07.047
Jaeger, D., Koukousaki, D., Bruen, C. A., Kalra, R., Pertuz, G. D. R., Sinanidou, A., Yannopoulos, N. J. P., Hodgson, L., Alexy, T., Gottula, A. L., et al. (2026) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2026.08.043
Kato, A., Matsushima, A., Sugiyama, M., Kubota, A., Imai, K., Miura, T., & Ode, Y. (2026) · Resuscitation Plus · doi:10.1016/j.resplu.2026.101482
Munasinghe, T., Shaw, K., Charteris, C., & Rotella, J. (2026) · Emergency Medicine Australasia · doi:10.1111/1742-6723.70355
“…arrest centre was associated with improved survival to hospital discharge (OR 1.85, 95% CI 1.74–2.84) and favourable neurological outcome at discharge (OR 2.22, 95% CI 1.74–2.84), although the certainty of evidence was very low given the predominantly observational study designs examined [8].”
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Metadata
- Authors
- Yeung, J., Matsuyama, T., Bray, J., Reynolds, J., & Skrifvars, M. B.
- Affiliations
- University of Warwick (GB)
- Kyoto Prefectural University of Medicine (JP)
- Monash University (AU)
- Michigan State University (US)
- University of Helsinki (FI)
- Corresponding author
- Yeung, J.
- Venue
- Resuscitation
- Publisher
- Elsevier BV
- Published
- 2019-04
- Volume
- 137
- Pages
- 102-115
- ISSN
- 0300-9572 (ISSN-L)
- OpenAlex
- W2913395504
- Cited by
- 116
- References
- 71
- Citations by year
- 2026: 8 · 2025: 13 · 2024: 18 · 2023: 9 · 2022: 18 · 2021: 29 · 2020: 13 · 2019: 7
- FWCI
- 4.28
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Resuscitation (publishedVersion)
- Monash University Research Portal (Monash University) (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Warwick Research Archive Portal (University of Warwick) (acceptedVersion)
- Työväentutkimus Vuosikirja (submittedVersion)
- Warwick Research Archive Portal (University of Warwick) (submittedVersion)
- Funders
- American Heart Association
- Topics
- Health Sciences › Medicine › Emergency Medicine › Cardiac Arrest and Resuscitation
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Mechanical Circulatory Support Devices
- Keywords
- out-of-hospital cardiac arrest, post-resuscitation care, neurological outcome, survival to hospital discharge, return of spontaneous circulation
- MeSH terms
- Adult, Cardiac Care Facilities, Humans, Survival Analysis, Cardiopulmonary Resuscitation, Out-of-Hospital Cardiac Arrest
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